Levitra (Vardenafil): Uses, Side Effects, Reviews
Vardenafil, often marketed under the name Levitra, is a prescription drug used to treat erectile dysfunction in men. A man with erectile dysfunction cannot maintain or get an erection. Typically, it occurs as a result of the penis’s arteries being overly narrow.
How does it work?
A penile erection causes the penis to swell with blood. Blood vessels that bring blood into the penis enlarge, or dilate, whereas blood vessels that remove blood constrict. Blood fills the two sizable chambers in the penis known as the corpora cavernosa.
An erection happens as the blood builds up in the penis. Vardenafil is a member of the group of medications known as phosphodiesterase type-5 (PDE5) inhibitors. A PDE5 inhibitor prevents PDE5 from causing artery constriction.
Vardenafil increases blood flow when a man is sexually aroused by relaxing the arteries. The active component affects the series of events that transpire inside the penis during arousal. Nitric oxide is released into a man’s penis when he is sexually aroused, which starts a series of events.
This results in the production of cyclic guanosine monophosphate by the enzyme guanylate cyclase (cGMP). Blood arteries that deliver blood to and from the penis are controlled by cGMP in terms of their contraction and dilatation, or expansion. The blood arteries that supply the penis expand as a result of the chemical reaction, whilst the blood vessels that remove blood from the penis contract.
Another enzyme, phosphodiesterase-5 (PDE5), degrades or eliminates cGMP. The blood vessels shrink back to their regular size after cGMP is eliminated, ultimately stopping the erection. PDE5 is prevented from degrading cGMP by vardenafil. This makes it possible for cGMP to function longer. As a result, it aids in erection extension.
Dose and usage of Levitra:
Vardenafil comes in tablets containing 2.5 mg, 5 mg, 10 mg, and 20 mg of the medication. Typically, the first dose is 10 mg. Vardenafil, which comes in 10-mg doses, is roughly similar to 50 mg of sildenafil, or Viagra. This is as a result of vardenafil’s differing chemical makeup from sildenafil.
Taken between 25 and 60 minutes before sexual activity. The impact can last up to five hours. Every 24 hours, a maximum of one tablet may be consumed.
Before consuming, orodispersible pills must dissolve on the tongue. Any type of drink should not be consumed together with these. In order for the medicine to work, the male must be sexually stimulated, therefore foreplay is usually required.
Vardenafil can be taken with or without food, however, it is not recommended to drink alcohol because it lowers the likelihood of achieving an erection. Alcohol may also make negative consequences more likely.
Side effects of Levitra
When using vardenafil, negative side effects and interactions are possible, just like with any drug. A headache will affect one in ten males.
Other typical negative effects include:
- Runny or congested nose
- Stomach Pain
These typically vanish within a few hours.
Other potentially harmful signs comprise:
- Hearing loss or ringing in the ears suddenly
- Chest pain and difficulty breathing
- Swelling in the hands, feet, ankles, or chest
If these occur, the patient should discontinue taking vardenafil.
An allergic response can sporadically happen. Hives, breathing problems, and swelling of the face, tongue, and throat may result from this. It may result in shock and be lethal. When these signs and symptoms show up, they should be handled as an emergency.
When an erection lasts longer than four hours, priapism, one of the very unusual side effects, may occur. The penis may suffer from this. The person should get medical help if an erection lasts too long.
A decline in eye blood pressure might cause visual abnormalities. The person might perceive objects as having a blue tint, and they might have trouble telling green from blue.
Very rarely, vision in one or both eyes may suddenly deteriorate. This can be a sign of heart disease, an eye ailment that already exists, excessive cholesterol, diabetes, or hypertension.
The patient should stop taking the drug and seek immediate medical attention if any unexpected loss of vision occurs.
Patients with other diseases like heart or coronary artery disease, diabetes, and excessive cholesterol are more likely to experience vision issues. If a person smokes or is older than 50, they are more prone to experience vision issues.
Interactions with other drugs:
If a man is taking nitrate medications for chest discomfort or heart issues, such as riociguat (Adempas), or other nitrate medications, he shouldn’t take vardenafil.
It shouldn’t be combined with poppers, which are recreational narcotics made of butyl and amyl nitrate.
Various other medications, including but not restricted to:
- Erectile dysfunction treatments
- Medications for blood pressure
- Heart rhythm issues
- Prostate issues
- Medicines for AIDS or HIV
Grapefruit juice should not be drunk when using vardenafil since it includes a component that increases the likelihood of side effects.
How can you prevent adverse effects?
It’s crucial to take the right dosage in order to prevent negative effects. The dosage that is right for you will be suggested by your doctor. This dosage should not be increased without first consulting your doctor, as doing so increases your risk of experiencing negative effects. It’s crucial that you don’t take more Levitra than the recommended 20 mg daily dosage.
Additionally, it’s critical that you let your doctor know if you’re taking any other drugs, as they may mix with Levitra and result in unfavourable side effects. Levitra and any other comparable medicine, such as Viagra or Cialis, cannot be taken together.
Viagra vs. Levitra
Levitra takes 60 minutes to start working in the body, compared to 30 to 60 minutes for Viagra. Both medications; effects linger for roughly 4 hours.
Levitra does not cause a rash or muscular aches, and it has fewer common adverse effects than Viagra. Both Viagra and Levitra have adverse effects that include changes in vision colour.
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