Advair Diskus
Pharmacokinetics
The study of a drug's absorption, distribution, metabolism, and elimination by the body is known as pharmacokinetics. Fluticasone and salmeterol are two drugs included in Advair Diskus. A corticosteroid called fluticasone lowers lung inflammation. Beta-adrenergic agonist salmeterol relaxes the muscles surrounding the airways. Using an inhaler device, both medications are administered orally. After that, the drugs enter the bloodstream via the lungs. The liver breaks them down, and the kidneys eliminate them. Fluticasone has a half-life of approximately 9 hours, while salmeterol has a half-life of approximately 12 hours. This indicates that half of the fluticasone must leave the body after 9 hours and half of the salmeterol must leave the body after 12 hours.
Drug Interactions
Other medications, vitamins, or herbal supplements you may be taking may have interactions with Advair Diskus. When a substance modifies how a drug functions, there is an interaction. This could be harmful or stop the medication from working properly. Your doctor needs to carefully monitor all of your medications to help you avoid interactions. Tell your doctor about all of the drugs, vitamins, and herbal remedies you are taking. Speak with your doctor or pharmacist to learn how this medication may interact with other medications you are taking.
The following is a list of some medications that may interact with Advair Diskus.
Interactions with other drugs
Other medications, including prescription and over-the-counter drugs, vitamins, and herbal products, can interact with fluticasone and salmeterol. Not all potential interactions are covered in this list. Inform your doctor about all of your current medications as well as any new or discontinued ones. This includes vitamins, herbal products, prescription and over-the-counter medications. If you are taking a monoamine oxidase inhibitor (MAOI), do not take Advair Diskus. Isocarboxazid, linezolid, phenelzine, methylene blue, rasagiline, selegiline, and tranylcypromine are examples of MAOIs.
Interactions with other substances
Alcohol or tobacco can affect how Advair Diskus works when combined with other medications. Fluticasone's effectiveness can be lowered and the risk of side effects increased by smoking. Ask your doctor for advice on how to stop smoking if you currently do so.
Side Effects
Serious side effects of Advair Diskus include:
headache and vertigo
nervousness
shaking hands in an uncontrollable manner
high blood pressure, a rapid heartbeat, or irregular heartbeat
tightness or pain in the chest
breathing difficulties coughing up blood or vomit that resembles coffee grounds
Immediately seek medical care if you experience any of these symptoms. Other less severe side effects of Advair Diskus include runny nose, sore throat, muscle pain, a mild headache ,gastrointestinal discomfort, vomiting, coughing.
Precautions and Warnings
Serious side effects of Advair Diskus include:
headache and vertigo
nervousness
shaking hands in an uncontrollable manner
high blood pressure, a rapid heartbeat, or irregular heartbeat
tightness or pain in the chest
breathing difficulties coughing up blood or vomit that resembles coffee grounds
Immediately seek medical care if you experience any of these symptoms. Other less severe side effects of Advair Diskus include runny nose, sore throat, muscle pain, a mild headache ,gastrointestinal discomfort, vomiting, coughing.
Dosage
Two daily inhalations of Advair Diskus are the recommended dosage. It is recommended to take the first dose in the morning and the second dose in the evening. There are two strengths of Advair Diskus: 50/250 mcg and 500/50 mcg. For those with asthma who also take beta-adrenergic agonists and other inhaled corticosteroids, there is a 50/250 mcg strength. For those with COPD who also take other inhaled corticosteroids, there is a 500/50 mcg strength.