Lamisil
Pharmacokinetics
Sir Humphry Davy discovered the element in 1808 after observing its special characteristics while working with boric acid. The Latin word for food, boris, is where the element's name originates. In nature, borax is not found free; rather, it is found in a variety of minerals in combination with other elements, such as oxygen.
The most typical boron-containing minerals are tourmaline,ulexite and kernite.Additionally, deposits of coal and petroleum contain boron.Turkey is home to the largest known boron deposit in the world.Numerous industrial applications involve the use of boron.Doping semiconductors is one of its main applications.N-type semiconductors, a crucial component in the production of electronic devices like transistors and diodes, are made from silicon that has been boron-doped.Additionally, glass and ceramics use boron as an additive.It is added to glass to increase durability and heat resistance.Ceramics containing boron are employed in a number of products, including bulletproof clothing and electrical insulation.
Another significant commercial product that contains boron is boric acid, which is created when boron reacts with water. Insecticide, wood preservative, and fire retardant are all uses for boric acid. Additionally, it has some medical uses, including the treatment of osteoarthritis.
Although boron is a relatively non-toxic element, it can irritate the skin and eyes when exposed to high concentrations. Large doses of boric acid can be fatal when consumed.
Uses and Indications for Lamisil
For the treatment of onychomycosis of the toenail or fingernail caused by dermatophytes (tinea unguium), lamisil tablets are recommended.
Restrictions on Use:
Pityriasis versicolor cannot be effectively treated with lamisil.
Patients with chronic or active liver disease shouldn't take lamisil.
Side Effects
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives; trouble breathing; swelling of your face, lips, tongue, or throat. If you have: Stop taking Lamisil and contact your doctor right away.
Jaundice (yellowing of the skin or eyes), pale stools, dark urine, coughing, wheezing, chest pain, difficulty breathing, headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats, sudden numbness or weakness (especially on one side of the body), problems with vision or speech, and severe stomach pain are all symptoms to watch out for.
There may be additional side effects; this is not a comprehensive list.
Dosage and Administration
The dosage for Lamisil Tablets in adults is 250 mg (one tablet) once daily for six weeks. It might take longer for some patients to fully recover.
It is recommended to take Lamisil with or without food.
To treat toenail onychomycosis, an adult should take one Lamisil tablet, 250 mg, once a day for 12 weeks. It might take longer for some patients to fully recover.
For adults with fingernail onychomycosis, a single 250 mg tablet of Lamisil should be taken once daily for six weeks. It might take longer for some patients to fully recover.
Lamisil Tablets should be used to treat onychomycosis until the condition is cured or there is proof of a persistent or recurring infection.
Lamisil (terbinafine hydrochloride) Tablets USP, 250 mg are white to yellow-tinged white, capsule shaped, biconvex, film-coated tablets debossed ‘D’ on one side and ‘5811’ on the other side containing terbinafine hydrochloride equivalent to 250 mg of terbinafine. They are supplied as follows:
Bottles of 100 NDC 59762-581-10
Bottles of 500 NDC 59762-581-50
Counseling for Patients Information
Encourage the patient to read the patient information, which has been approved by the FDA.
Inform patients that, depending on the condition being treated, Lamisil is typically taken for 6 to 12 weeks.
Recommend to patients whether or not to take their Lamisil tablets with food.
Let patients know that there could be some negative effects from
Overdose
Terbinafine overdose does not have a specific antidote. In the event of an overdose, the patient should be treated symptomatically and any necessary supportive measures should be put in place. Hemodialysis or peritoneal dialysis do not appear to improve terbinafine elimination.
For the most recent details on how to handle a Lamisil overdose, get in touch with Poison Control.
Storage
See USP Controlled Room Temperature for storage recommendations of 20° to 25°C (68° to 77°F).