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Colofac (mebeverine hydrochloride)
Jordan Christchurch reviewed
"Fast, easy to use and very responsive customer service. Prices are also very competitive."
RJ Layton reviewed
"5 Star service is so much easier than going to my local pharmacy, especially when feeling under the weather."
Bianca Carthright reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
Colofac (mebeverine hydrochloride)
68 Reviews
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Colofac is a medication that can help to relieve the symptoms of cramping associated with IBS and menstruation. The active ingredient mebeverine hydrochloride is an antispasmodic that relaxes the muscles in your abdomen, reducing the painful cramping.

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Pricing is provided as a reference. Treatment will be shown after completing the consultation. The final decision on issuing this medication remains with the prescriber.
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Jordan Christchurch reviewed
"Fast, easy to use and very responsive customer service. Prices are also very competitive."
RJ Layton reviewed
"5 Star service is so much easier than going to my local pharmacy, especially when feeling under the weather."
Bianca Carthright reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
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What is Colofac MR?

Colofac is a medication that contains the antispasmodic mebeverine hydrochloride. As an antispasmodic medication, it treats muscle spasms associated with painful cramping due to IBS or period pain. The medication comes as both a tablet and a capsule.

How does it work?

The medication relaxes the muscles in the abdomen which leads to a reduction of cramping and discomfort. 

Is Colofac MR right for me?

Colofac can be taken by most adults and for children over 10 years. It does not cause many side effects and is safe to use.

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects, however, these do not always occur.

  • Mild itchy skin rash

Disclaimer: This website does not constitute as medical advice, you should also consult with a doctor before taking medication. If you experience any major reactions to any medication you are taking, you must seek immediated medical attention.


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or envelopes. You will not have to worry about any content descriptions, and the package will be for your eyes only!


Commonly Used Dosage Guidelines for Colofac

For capsules

  • Take 1 capsule morning and evening, swallowing whole with water. Do not chew.

For tablets

  • Take 1 tablet three times daily, preferably 20 minutes before meals.

Disclaimer: This website does not provide medical advice. 

No information listed on this website is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undergoing a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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How it works
Complete a Quick & Free Online Consultation

This is a quick process and should only take 1 - 2 minutes. All of your answers are confidential, and just like a GP consultation, you will know what treatment is most suitable for you instantly upon completion.

Place Your Order for Colofac (mebeverine hydrochloride)

Once you have completed the quick online form, select the treatment option most suitable to you and checkout securely.

Express Next Day Delivery

A medical professional will review your answers to the online medical consultation and determine if it’s safe to prescribe and what treatments are available.

Buy Colofac (mebeverine hydrochloride) Online

Please note the information below is intended for general knowledge, please read the patient information leaflet and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

You can buy Colofac (mebeverine hydrochloride) online from our UK-registered online pharmacy partners. Complete an online consultation form and our system will show you if you are eligible to purchase Colofac (mebeverine hydrochloride) online. Our pharmacists will then review your order of Colofac (mebeverine hydrochloride) and dispatch it discreetly to your address.

How to buy Colofac (mebeverine hydrochloride) online?

You can buy Colofac (mebeverine hydrochloride) by following the following steps.

  1. Fill out our online consultation form
  2. If you are eligible to purchase Colofac (mebeverine hydrochloride) you will be shown it as one of your treatment options
  3. Pay online and receive your order to the comfort of your chosen address

Can I get Colofac (mebeverine hydrochloride) on the NHS?

Whether or not you can get Colofac (mebeverine hydrochloride) on the NHS is dependent on your local guidelines and eligibility status. It is best to contact your local GP service if you are unsure of whether you can get Colofac (mebeverine hydrochloride) from the NHS.

Can you get Colofac (mebeverine hydrochloride) over the counter?

No, you can’t get Colofac (mebeverine hydrochloride) over the counter without a prescription or consultation. Colofac (mebeverine hydrochloride) is a regulated medication so all purchases need to have a prescription and/or suitable consultation form completed.

Can I buy Colofac (mebeverine hydrochloride) online even if I have never taken it before?

A prescribing pharmacist will need to review your consultation form before the medication can be dispatched. One of our partner prescribing pharmacists will review the consultation form and will decide if you are eligible to buy Colofac (mebeverine hydrochloride).

Is Colofac (mebeverine hydrochloride) safe?

If you have been prescribed Colofac (mebeverine hydrochloride) then it is at the discretion of the prescriber.

However, all medications can potentially have adverse effects and should be taken exactly as prescribed. If you experience any side effects when taking Colofac (mebeverine hydrochloride) then you should contact a doctor immediately.

Are there any foods that should be avoided when taking Colofac (mebeverine hydrochloride)?

We recommend you read the patient information leaflet for this product thoroughly before taking the treatment. This is essential to understanding any interactions that can occur and to take the medication safely.

How long does Colofac (mebeverine hydrochloride) take to work?

The time it takes for a Colofac (mebeverine hydrochloride) to work can vary greatly depending on several factors, such as the strength, the individual's age, weight, and overall health, as well as any potential interactions with other medications or substances. Generally, the effects of Colofac (mebeverine hydrochloride) may be noticeable within the time frame outlined by the prescribing pharmacist. It is important to follow the prescribed dosage and instructions provided by your healthcare professional, and to consult them if you have any concerns or questions about the medication's efficacy or possible side effects.

How effective is Colofac (mebeverine hydrochloride)?

The effectiveness of Colofac (mebeverine hydrochloride) can vary significantly depending on various factors, such as the dosage, the condition being treated, the individual's age, weight, and overall health, as well as the presence of any other medications or substances that might interact with it. While some medications may be highly effective for certain individuals and conditions, others might experience a lesser degree of benefit or may require adjustments to the dosage or additional treatments to achieve the desired results.

What are the risks of taking Colofac (mebeverine hydrochloride)?

At Welzo, we are dedicated to providing our customers with accurate and comprehensive information about medications. We believe that understanding the potential risks and side effects associated with a medication is essential for making informed decisions about your health. This guide outlines some general considerations for assessing the risks of medication and includes references to the National Health Service (NHS) for further information.

  1. Read the Patient Information Leaflet (PIL): Every medication comes with a Patient Information Leaflet, which provides essential details about the drug, its uses, and potential side effects. Be sure to read this leaflet carefully before starting any new medication. The Electronic medicines compendium has a list of patient leaflets. you can visit by heading to
  2. Be aware of potential side effects: All medications have the potential to cause side effects, ranging from mild and short-lived symptoms to more serious, long-lasting issues. It's important to understand the possible side effects of a medication and how to manage them. The NHS has a helpful resource on managing medication side effects, while also speaking to a healthcare professional is important in understanding any potential risks of taking Colofac (mebeverine hydrochloride).
  3. Interactions with other medications: Some medications may interact with others, leading to increased side effects or reduced effectiveness. Make sure to inform your healthcare professional about all the medications and supplements you are currently taking. The NHS offers a useful tool for checking potential drug interactions here.
  4. Contraindications and precautions: Certain medical conditions or factors may make it unsafe for you to take a particular medication. Before starting any new medication, inform your healthcare professional about your medical history and any current health issues. The NHS provides more information about contraindications and precautions here.
  5. Appropriate use and dosage: It's crucial to follow the prescribed dosage and instructions for taking a medication to ensure its effectiveness and minimise the risk of side effects. The NHS has a useful guide on using medicines safely here.
  6. Monitoring and follow-up: Some medications require regular monitoring or follow-up appointments with your healthcare professional to ensure their safety and effectiveness. Be sure to schedule and attend these appointments as needed.

Can I buy Colofac (mebeverine hydrochloride) in the UK?

Yes, you can buy Colofac (mebeverine hydrochloride) in the UK with a valid prescription and or consultation form. Colofac (mebeverine hydrochloride) is available in the UK for purchase from local pharmacies with a valid prescription and or consultation and to purchase from Welzo if in stock. It is imperative that you ensure that the pharmacy you are buying the products from is licensed and registered with the General Pharmaceutical Council (GPhC).

Where can I buy Colofac (mebeverine hydrochloride)?

You can buy Colofac (mebeverine hydrochloride) online from upon completion of a consultation form and a free review from a prescribing pharmacist.

Are Colofac (mebeverine hydrochloride) users satisfied with the product?

We have a list of reviews from customers taking Colofac (mebeverine hydrochloride) at the bottom of this page. For more information of the reviews of Colofac (mebeverine hydrochloride) head over to for further details.

Can I buy Colofac (mebeverine hydrochloride) from an online pharmacy?

Yes, you can purchase Colofac (mebeverine hydrochloride) from an online pharmacy. However, this is dependent on your eligibility for the medication.

How much does Colofac (mebeverine hydrochloride) cost?

The costs of Colofac (mebeverine hydrochloride) are listed at the top of the page. Pricing is provided as a reference as treatment options will be shown upon completing the consultation form.

What is IBS?

IBS is a disorder that affects the large intestine, or colon. The exact cause of IBS is unknown, but it is thought to be related to a problem with the way the nerves and muscles in the intestine work together. Symptoms of IBS can include abdominal pain, bloating, gas, diarrhoea, and constipation. IBS is a chronic condition, meaning it can last for months or even years. There is no cure for IBS, but there are treatments that can help to relieve the symptoms.

What can Colofac be used for?

Colofac is a medication that can be used to relieve the symptoms of irritable bowel syndrome (IBS). IBS is a condition that affects the gastrointestinal tract and can cause symptoms such as abdominal pain, bloating, constipation, and diarrhoea.

Is this medication suitable for me?

Please get in touch with a doctor if you are unsure what medication is suitable for you. You can also complete our online consultation form to check your eligibility for the product.

How is the medication delivered?

All orders placed before 14:00 from Monday to Friday will be dispatched that day. The orders are sent using 24 Hour Tracked delivery provided by Royal Mail. Items will usually arrive the very next day after the order has been placed. We also provide tracking for your orders to check the status and location of your parcel. All our medication is packaged in plain confidential padded white or brown envelopes. This ensures that your orders are discreet, and the content of the orders will be for your eyes only.

What is the dosage for Colofac?

The usual adult dose of Colofac is one tablet (135mg) two or three times daily. The tablets should be taken with or after food.

For children aged 12 years and over, the usual dose is a one-half tablet (67.5mg) two or three times daily.

Does Colofac work straight away?

In some people, Colofac can work within a few days. For others, it may take up to two weeks for the full effects to be felt. If you don't notice any improvement after four weeks of treatment, speak to your doctor.

How do I order my medication?

Some products only require an online consultation which approximately takes 1 minute to complete, enabling you to then buy the product. Other products will also require a prescription; in this case, you will need to complete the online consultation, and then one of our partner pharmacy prescribers or doctors will review the online consultation questions and approve the order for delivery if you are eligible to purchase the item.

Can I cancel or return my order?

For non-medicinal products, you are eligible to return the product within 14 days of receipt in the same packaging you received. For medicinal products, you are eligible to cancel the order only until it has been dispatched. From that point forward, you are no longer eligible to return the order.

You have the right to cancel your order for medication up to the point when your medication is dispatched.

Why Welzo
Discreet next day shipping
Discreet next day shipping

Welzo prescription medication is shipped out for next-day delivery in discreet packaging.

Trusted UK Pharmacy
Trusted UK Pharmacy

Welzo only works with UK-based pharmacies. All our medication is authentic and issued by GPhC-registered pharmacies and prescribers.

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Supportive & Caring

Our team of clinicians and health experts can support you along every step of your treatment journey.

Why Welzo

Customer Reviews

Based on 1 review
Serina Zagen

I appreciate the attention to detail and care provided by's prescription delivery team in ensuring the safe and timely delivery of my prescriptions.