Domperidone is a medication used to treat vomiting and nausea caused by drugs used to treat Parkinson's disease. Domperidone is an antiemetic and prokinetic medication that works to increase the contractions of the stomach and bowel to allow for better food movement through the stomach.
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What is Domperidone?

Domperidone is a prokinetic and antiemetic drug. These tablets are used for digestive and stomach issues, e.g., discomfort, pain, nausea and vomiting. 

How does it work?

This drug belongs to a class of drugs called dopamine antagonists. It blocks the dopamine receptors in the gut and increases the muscular contractions and movements in the intestine and stomach, facilitating food movements. It also affects the brain to reduce vomiting and nausea. It also causes an increase in the production of prolactin hormone, which increases milk production. 

Is it suitable for me?

It is suitable for adults and adolescents more than 12 years of age. It is suitable for men and women having the following issues nausea, vomiting and symptoms of gastric stasis, e.g., indigestion, anorexia, belching, bloating etc. 

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Side Effects

All medications can cause potential side effects, below we have listed some potential side effects, however, these do not always occur. The common side effects are;

  • Drowsiness
  • Anxiety
  • Low libido
  • Diarrhoea
  • Itching and rashes on the skin
  • Weakness
  • Tender and painful breasts
  • Nervousness
  • Breast enlargement
  • Difficulty urination
  • Dry Mouth

Some serious side effects requiring emergency care are;

  • Seizures
  • Allergic reaction
  • Unusual fast and irregular heartbeat

Disclaimer: This website does not constitute as medical advice, you should also consult with a doctor before taking medication. If you experience any major reactions to any medication you are taking, you must seek immediate medical attention.


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All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.


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The commonly used dosage guidelines for Domperidone-10mg tablets.

  • The recommended dose is a single 10mg dose taken three times daily. However, the doctor may recommend upto 4 tablets depending on the situation. 

For more dosing information, consult the doctor or patent leaflet. 

Disclaimer: This website does not provide medical advice. No information listed on this website is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undergoing a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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Can I use Domperidone tablets during pregnancy?

Little data is available on Domperidone safety in pregnancy. It is better not to use it unless asked by the doctor.

How safe are the Domperidone tablets?

It is safe and well-tolerated by the majority of the people. However, it is better to start with a low dose and inform the doctor or pharmacist if you are taking drugs for heart issues and other related problems.

Can I drive after taking Domperidone tablets?

Drowsiness is one of the side effects of these tablets. Therefore, it is better not to drive, work on machinery or do anything that needs focus and attention.

Can Domperidone tablets cause weight gain?

Domperidone is a prokinetic drug and increases the motility of the stomach and intestines. More mobility means less gastric emptying time, more food intake, and consequently, more chances of obesity and related issues, e.g., diabetes.

How should Domperidone tablets be stored?

These tablets should be stored at a stable room temperature of 20-25C, away from direct sunlight and out of reach of children.

How quickly does Domperidone work?

For most people, its effects are noticeable within 30-60 minutes. However, if it is ineffective, consult the doctor for a change in the drug.

Can Domperidone be taken before going to bed?

The best time to take it is 15-30 minutes before the meal. It can be used before bedtime or as the physician asks.

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