Premique is an HRT medication that supplies a low dose of the two female hormones, oestrogen and progestogen. Hormone Replacement Therapy (HRT) medicines are often prescribed to lessen the symptoms associated with menopause.
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What is Premique?

Premique is an oral hormone replacement therapy (HRT). It has conjugated oestrogen and a synthetic progesterone analogue and is a period-free therapy. It replaces the depleted oestrogen in your body, thus addressing menopause-associated issues. Low-dose variants are also available which are suitable for women experiencing more side effects. 

How does it work?

It has medroxyprogesterone acetate and conjugated oestrogen as active drugs. The conjugated oestrogens work like your body's natural oestrogen and cover the side effects of depleted oestrogen. 

If the woman has a uterus, using oestrogen-only pills will cause the growth of the uterine lining. Therefore, these tablets have progesterone to balance the effects of the oestrogen. 

Are the Premique tablets suitable for me?

It is suitable for adult women experiencing oestrogen deficiency due to menopause. If the falling oestrogen is not due to menopause, consult the gynaecologist. 

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Side Effects

All medications can cause potential side effects, below we have listed some potential side effects, however, these do not always occur. The side effects include;

  • Changes in the sexual desire
  • Mood swings
  • Fluid retention
  • Indigestion
  • Headaches backaches

Each individual may experience different side effects or the same effects with different intensities. You need to consult the doctor for guidance. 

Disclaimer: This website does not constitute as medical advice, you should also consult with a doctor before taking medication. If you experience any major reactions to any medication you are taking, you must seek immediate medical attention.


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.


Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!


The commonly used dosage guidelines for Premique tablets.

  • The low-dosage premium tablets contain 1.5mg of medroxyprogesterone and 300mcg of conjugated oestrogen.
  • The common recommendation is to take one pill daily for a whole month (28 days). To get consistent results, ensure you are not missing any day. Preferably, the tablets should be taken at the same time each day. 

Disclaimer: This website does not provide medical advice. No information listed on this website is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undergoing a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Premique Patient Leaflet

To view the Premique Patient Leaflet, click here.

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Once you have completed the quick online form, select the treatment option most suitable to you and checkout securely.

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We will dispatch your order using our express next-day courier service from our pharmacy partners across the UK. You will receive your treatment discreetly to the comfort of your home/ selected address. 

What should I do in case of a missed Premique pill?

You need to take a missed pill as soon as you remember. In case you have missed more pills, take only the recent one. A missed pill can cause breakthrough bleeding. But don't take the double pills in any case.

How can I purchase Premique tablets?

You can order it online through Welzo. However, you will need to complete an online consultation, which will decide if you are eligible for this medication.

Can Premique tablets cause weight gain?

Yes. Weight gain is one of the side effects of Premique tablets. If you are concerned about weight gain, consult the doctor.

What are the contraindications of using Premique tablets?

There are some situations under which the use of premium tablets is guarded, and you need to consult a gynaecologist. These are;

  • A history of depression, asthma, gallbladder disease, breast cancer etc. 
  • Have or had a history of coronary heart disease or stroke
  • Have epilepsy, liver diseases, obesity, hypertension, clotting disorders etc.
  • In case of breastfeeding or pregnancy

Are higher doses of Premique available?

The higher dose version of Premique (0.625mg/ 5mg) was available, but it has been discontinued.

Can the use of Premique tablets cause hair loss?

Some HRTs cause or exacerbate female pattern baldness. However, hair loss is not an indicated side effect of Premique.

Why Welzo
Discreet next day shipping
Discreet next day shipping

Welzo prescription medication is shipped out for next-day delivery in discreet packaging.

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Trusted UK Pharmacy

Welzo only works with UK-based pharmacies. All our medication is authentic and issued by GPhC-registered pharmacies and prescribers.

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Supportive & Caring

Our team of clinicians and health experts can support you along every step of your treatment journey.

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