Xigduo is a prescription-only medicine used to treat type 2 diabetes when metformin alone is ineffective, by helping to lower blood glucose levels. 
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What is Xigduo?

Xigduo is an oral anti-diabetic medication that is used for the treatment of type 2 diabetes. This medication is usually prescribed if your diabetes has not been effectively treated with other medications or lifestyle changes.

How does it work?

Xigduo contains the active ingredients dapagliflozin and metformin. Dapagliflozin works by removing excess sugar from the body via urine. This then lowers the sugar levels in your blood and can also be useful in preventing heart disease. Metformin works by inhibiting glucose production in the liver.

Is Xigduo suitable for me?

This medication is usually prescribed when lifestyle and diet modifications have not been enough to treat diabetes. There are several pre-existing medical conditions and medications that are not compatible with this medication. Consult with your doctor before beginning this medication.

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects, however, these do not always occur.

  • Urinary tract infection
  • Fever and/or chills
  • Burning sensation when passing water (urinating)
  • Pain in your back or side
  • Low blood sugar
  • Shaking, sweating, feeling very anxious, fast heart beat
  • Feeling hungry, headache
  • Change in vision
  • A change in your mood or feeling confused
  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach ache
  • Loss of appetite
  • Genital infection (thrush) of your penis or vagina

Disclaimer: This website does not constitute as medical advice, you should also consult with a doctor before taking medication. If you experience any major reactions to any medication you are taking, you must seek immediate medical attention.


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All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!


Commonly Used Dosage Guidelines for Xigduo.

The amount of medication you will take may vary depending on the state of your condition and your current medication. Your doctor will tell you exactly which strength of this medication to take. 

  • The recommended dose is one tablet twice a day, once in the morning (breakfast) and once in the evening (dinner)
  • Swallow the tablet whole with half a glass of water
  • Take your tablet with food to reduce the side effects in the stomach.

Disclaimer: This website does not provide medical advice. No information listed on this website is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undergoing a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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What is the difference between metformin and Xigduo?

Xigduo contains the ingredient metformin, which works to inhibit the glucose produced in the liver.

What if I take more Xigduo than I should?

If you've taken more of this medication prescribed for you, you may experience lactic acidosis. The symptoms of lactic acidosis include: 

  • Nausea or vomiting
  • Stomach ache
  • Muscular cramps
  • Severe tiredness 
  • Difficulty breathing

If this occurs, you may need immediate hospital treatment as it may lead to a coma. Stop taking this medicine immediately and contact a doctor or the nearest hospital straight away.

How long does it take for Xigduo to start working?

Diabetes may not show any symptoms so you may not feel any difference when taking this medication. 

What should I do if I miss a dose of Xigduo?

If you've missed a dose, then you need to take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take a double dose. 

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