Viread

An antiviral drug called Viread (tenofovir disoproxil fumarate) stops the human immunodeficiency virus (HIV) from proliferating in your body.HIV, a virus that can lead to acquired immunodeficiency syndrome (AIDS), is treated with Viread.HIV and AIDS are not curable with Viread. In order to better understand Viread, this article is meant to provide information to Welzo users.

Health Benefits of Viread

Viread can assist with:

- Lower your body's HIV concentration

- Improve your immunity

- Lessen your chance of HIV transmission to others

– Enhance your standard of living.

Side Effects

Serious negative effects of Viread include:

- Kidney dysfunction or problems. If you have ever had kidney issues, are 65 years of age or older, are taking other drugs that can damage your kidneys, or take Viread along with adefovir (Hepsera) or another drug that contains tenofovir, your risk may be increased. If you experience any kidney issues, such as a decrease in urine production, blood in your urine, a change in the color of your urine, or pain while urinating, call your doctor right away.

- Low phosphate levels in your blood. Bone and tooth health depend on phosphorus. If you experience any symptoms like muscle aches, bone pain, or weakness, let your doctor know.

- Lactic acidosis (excessive lactic acid production)

Viread may also result in less severe side effects like:

- Migraine

- Diarrhea

- Diarrhea

- Vomiting

- Dizziness or upset stomach

Skin rash

Dosage 

Viread should be taken once daily at a dose of 300 mg for both adults and kids who weigh at least 35 kg. The recommended dose for kids under 35 kg is determined by their body weight.

It is possible to take Viread with or without food.

Viread should be taken as soon as you remember if you miss a dose. Skip the missed dose and resume your regular dosing schedule if your next dose is almost due. Never combine two doses at once.

Interactions

There could be drug interactions with Viread. Inform your doctor about all prescription, over-the-counter, and dietary supplements you are taking. Viread should only be taken during pregnancy if it has been prescribed. This drug is excreted in breast milk. Before breastfeeding, speak with your doctor.

Mechanism of Action 

Reverse transcriptase is the enzyme that Viread inhibits in order to function. The HIV virus cannot replicate without reverse transcriptase. Viread helps strengthen your immune system and lowers the amount of HIV in your body by blocking this enzyme. Because of this, you are less likely to contract HIV and spread the disease to others.

Pharmacokinetics 

After oral administration, Viread is quickly absorbed and reaches peak plasma concentrations in 2 to 4 hours. Viread has a bioavailability of about 60%. Plasma proteins only contain a very small amount of viread (0.4%). Viread is primarily eliminated by the kidney through glomerular filtration and tubular secretion. Following multiple once-daily doses in subjects with normal renal function, the median apparent terminal elimination half-life of Viread is 17 hours. Viread's elimination half-life extends in patients with impaired renal function, and its systemic exposure (AUC) rises dose-dependently.