Top Vitamin B9 (Folate) Supplements of 2025

The majority of people instantly associate folate with pregnancy. Although that is undoubtedly one of its most significant functions, folate is a nutrient that benefits people of all ages and stages of life.

The benefits of folate are far more extensive than most people realise, and it is really one of the most studied vitamins available. Folate is essential for maintaining the proper functioning of your body, from assisting in the synthesis of red blood cells to promoting the production of energy. Because it helps control homocysteine levels, a substance connected to heart disease and cognitive decline, it is also essential for heart and brain health. 

Of course, folate is well recognised for its function in preventing neural tube abnormalities during pregnancy, but new studies reveal that it’s just as vital for overall well-being. Whether you're wanting to boost your mental health, lessen your risk of cardiac problems, or just feel more energized, folate plays a role in all of it.

We've evaluated a few of the best folate supplements available to ensure you're getting the proper one. We examined a variety of items before concentrating on premium forms, such as methylfolate, which is the most bioavailable form and can be immediately utilized by your body. We've compiled the top folate supplements for 2025 based on expert advice and the most recent findings.

What is Vitamin B9 (Folate)?

A vital water-soluble vitamin that is essential for many physiological processes is folate, sometimes referred to as vitamin B9. In order to maintain a healthy immune system and proper cellular function, this vitamin is necessary for the synthesis of DNA and RNA as well as the production of red and white blood cells. By controlling homocysteine levels, folate also aids in the conversion of carbohydrates into energy, promotes cognitive function, and is crucial for preserving cardiovascular health.

Folate is especially important during times of rapid growth, like pregnancy, infancy, and adolescence, where it supports the development of the fetus and the formation of neural structures. Deficiency, especially during pregnancy, can result in neural tube defects, which can lead to serious congenital disabilities like spina bifida. Folate supplements are strongly advised for women of childbearing age because they have been shown to reduce the risk of such defects by up to 70%. 

Although folate is naturally found in a variety of foods, such as citrus fruits, leafy green vegetables, and legumes, many people find it difficult to get enough folate from their diet alone, which has led to a greater reliance on folate supplements to ensure optimal intake, especially among those with dietary restrictions, certain medical conditions, or genetic mutations that impair folate metabolism.

Benefits of Vitamin B9 (Folate)

Folate, often known as vitamin B9, is an essential nutrient that is important for many parts of health. It is crucial for fetal development and is most well-known for preventing neural tube abnormalities during pregnancy. But that's only one of its many advantages. 

Folate is essential for cognitive function, helps control heart health by reducing homocysteine levels, and promotes energy generation by transforming food into usable energy. It's also crucial for mental health since it helps control mood and may help treat mental health issues like anxiety and sadness. It is necessary for both mental and physical health, and research even suggests that it may help prevent dementia and cognitive decline as we age.

Folate is also essential for cell growth and repair in addition to its roles in pregnancy and mental health. It promotes healthy skin, hair, and nails by aiding in the production and regeneration of new cells, as well as  for tissue regeneration and wound healing when you're recuperating from a sickness or accident. Because it promotes healthy cell growth, folate's function in DNA synthesis is also essential for lowering the risk of cancer. Making sure you're getting enough folate, whether via supplements or meals like leafy greens, can be a wonderful approach to improve your general health and wellness because of all these numerous advantages.

Our Top Picks

Best Overall: Thorne 5-MTHF Methyl Folate

Best Natural Source: Together Health Natural Folate

Best Value: Osavi MethylFolate & Methyl

Best Liquid Option: LLF1 Folate 5-MTHF Liposomal

Best for Energy and Vitality: Life Extension Optimized Folate

Best Vegan-Friendly: Jarrow Formulas Methyl Folate

Thorne 5-MTHF Methyl Folate

5-MTHF Thorne Five milligrammes of 5-MTHF (5-methyltetrahydrofolate), the active form of folate (vitamin B9), are found in the dietary supplement Methyl Folate. This bioavailable form promotes general wellbeing, brain function, and cardiovascular health. There are 60 capsules in each container.

Why we like it: 5-MTHF Thorne Methyl Folate is unique because it contains 5-MTHF, the bioactive form of folate, which guarantees the nutrient's effective absorption and utilisation by the body. For those seeking maximum effectiveness, this makes it a great option. It has numerous advantages for general health, such as promoting brain and cardiovascular health, in addition to maintaining appropriate folate levels.

Where to Buy and Price: For a total of 60 veg capsules that offer consistent nourishment for two months, you can get it at Welzo for £66.77.

Product Review: Reviews of Thome Methyl Folate are generally positive, indicating its effectiveness in promoting overall health. Customers like the premium formulation and the advantages of the active form of folate.

Together Health Natural Folate

Together Health Natural Folate is a spinach-based vitamin that has 400 microgrammes of natural folate each capsule. Active forms of folate, like 5-MTHF, are provided by this natural alternative to synthetic folic acid while retaining the beneficial co-nutrients of spinach. The product is pure and unadulterated since the spinach is grown without the use of chemical pesticides or herbicides. 

Why we like It: Together Health Natural Folate is unique due to its careful preparation and natural source. It comes from spinach and offers folate in its natural form, which promotes better body absorption and utilisation. The necessary 400 mcg of folate, which is particularly important for fetal development during pregnancy, is present in this supplement. Additionally, the spinach is grown without the use of synthetic pesticides or herbicides, and its ingredients are pure and devoid of artificial additions and processing aids.

Where to Buy and Price: For a price of £4.56 you can get a high quality Together Health Natural Folate at Welzo.

Product Review: The efficacy and purity of natural folate are highly acclaimed. Customers value Bodykind's natural product sourcing and lack of artificial ingredients. Similarly, evaluations praise Ocado's use of nutritious ingredients and highlight how suitable it is for pregnant women. 

Osavi MethylFolate & Methyl

Bioactive forms of methylfolate and methyl-B12 are present in the vegan dietary supplement Osavi MethylFolate & Methyl-B12. There are 60 pills in each container, which support general vitality, cognitive function, and energy generation.

Methyl-B12 supports neurons function, red blood cell production, and energy metabolism, whereas methyl folate aids in DNA synthesis, cell division, and cardiovascular health by controlling homocysteine levels.

Why We Like It: This supplement provides essential nutrients in easily absorbed forms for maximum effectiveness and absorption. The vegan pills are a safe and natural substitute because they don't include any dangerous substances. People with dietary restrictions or those who have trouble absorbing conventional sources of folate can particularly benefit from it. It is a flexible option for enhancing general well-being because of its ability to increase energy, mental clarity, and heart health.

Where to Buy and price: Currently, Osavi MethylFolate & Methyl is available for you at Welzo for £7.04

Product Review:Consumers typically value the product's superior composition and obvious effects on mental clarity and vigour. Others report improved cardiovascular and cognitive health, and many people adore the clean, vegan-friendly ingredients. According to a number of consumers, those with dietary limitations or problems with absorption benefit most from it.

LLF1 Folate 5-MTHF Liposomal

Folate 5-MTHF LLF1 Liposomal is a high-end folate supplement that was created with cutting-edge liposomal technology to enhance bioavailability and absorption. It ensures that the body uses 5-MTHF, the physiologically active form of folate, effectively by delivering it straight to the cells. This supplement works particularly well for those with digestive issues that affect the absorption of folate or genetic abnormalities (such mutations in MTHFR). In addition to supporting overall health, LLF1 Folate aids in DNA synthesis, cell division, and energy production.

Why we like it: We acknowledge the innovative method to folate supplementation taken by LLF1 Folate 5-MTHF Liposomal. Compared to traditional folate supplementation, the novel liposomal delivery technique enhances absorption and increases efficacy. Incorporating 5-MTHF, the active and usable form of folate, ensures optimal body utilisation by removing metabolic conversion. All vital functions, such as energy production, cognitive function, and cardiovascular health, are supported by this supplement. Additionally, its superior formulation—which is free of artificial components, non-GMO, and suitable for vegetarians—showcases its commitment to efficacy and purity.

Where to Buy and Price: You can get LLF1 Folate 5-MTHF Liposomal - 60ml - lipolife at Welzo for £13.01.

Product Review:Customers praise LLF1 Folate 5-MTHF Liposomal for addressing folate insufficiency issues and increasing energy levels. Numerous users highlight how it can help those with MTHFR mutations, pointing to notable improvements in cognitive function and general well-being. Some analyses suggest a little higher cost, which is supported by the advantages of absorption and better quality.

Life Extension Optimized Folate

Life Extension Each vegetarian tablet of Optimised Folate, a high-end nutritional supplement, has 1700 mcg of folate. For those who want to boost their consumption of folate, particularly those who want to enhance their cardiovascular health, red blood cell production, and DNA synthesis, this supplement is essential.

Because it reduces the risk of neural tube defects, folate is particularly crucial for expectant mothers. One hundred pills are included in each container, guaranteeing a continuous supply of this essential B-vitamin.

Why We Like It: Life Extension Optimised Folate is a great option for those wishing to boost their folate consumption because of its high dosage (1700 mcg each pill). The vegetarian pills are perfect for a range of dietary needs because the recipe is optimised for maximum absorption and they don't include any common allergens. Additionally, it supports vital processes including DNA synthesis and the production of red blood cells, which are advantageous for cardiovascular and general health.

Where to Buy and Price: You can get Life Extension Optimized Folate, 1700 mcg - 100 vegetarian tabs at the price of £13.11 at Welzo

Product Review: Life Extension Because of its potency and capacity to enhance overall health, Optimised Folate has received overwhelmingly good reviews. The 1700 mcg of folate per tablet, which meets daily dietary needs and emphasises the vitamin's vital role in DNA synthesis, cell division, and red blood cell production, is valued by consumers. Its excellent bioavailability, vegetarian friendliness, and allergy-free status attract a lot of clients. Several folks said they felt more invigorated after incorporating it into their routine.

Jarrow Formulas Methyl Folate

The premium dietary supplement Jarrow Formulas Methyl Folate, 400mcg, supports overall health. A two-month supply of this essential nutrient is provided by the 60 vegetarian capsules in each bottle. A physiologically active folate that is readily absorbed and used by the body, methyl folate (L-5-MTHF) is an ingredient in the product. Because methyl folate is more bioavailable than synthetic folic acid, it's a great option for those with genetic disorders that affect folate metabolism. This supplement supports fetal development, DNA synthesis, cardiovascular health, and cognitive function.

Why we like it: Jarrow Formulas Methyl Folate is lauded for its easily absorbed and effective folate. Each 400 mcg capsule supports DNA repair, neurotransmitter generation, and cardiovascular health. It's beneficial to pregnant women as it lessens risks of neural tube abnormalities. The supplement accommodates various dietary needs being gluten-free, soy-free, dairy-free delivered in simple-to-take vegetarian capsules.

Where to Buy and Price: Jarrow Formulas Methyl Folate, can be found at Welzo for the price of £9.20.

Product Review: Consumers express satisfaction with this product, with many praising its ability to improve mental clarity, energy levels, and general wellness.

Summary

Folate, sometimes referred to as vitamin B9, is a water-soluble vitamin that is essential for DNA synthesis and repair, cell division, and the creation of red blood cells. It is crucial for expectant moms because it encourages embryonic growth and reduces the risk of neural tube abnormalities.

Even while foods like citrus fruits and leafy greens contain it, supplements are usually needed to ensure adequate intake. They commonly employ methylated folate (bioactive form, like 5-MTHF) or synthetic folic acid, which the body can easily use even when there are genetic disorders like MTHFR that hinder the metabolism of folic acid. It maintains cardiovascular health by reducing homocysteine levels, which are associated with a higher risk of heart disease, and it also enhances cognitive function, energy, and emotional stability.

Frequently Asked Questions

What is methylfolate? Is it better than folic acid?

Methylfolate is the active form of folate, which means your body can use it right away without having to convert it. It is especially beneficial for persons who have genetic variants that make it difficult for their systems to metabolize folic acid. It's a more bioavailable form of folate, which means your body can absorb and use it more efficiently.

How much folate should I be getting each day?

For most adults, about 400 mcg a day is recommended. Pregnant women needs it more —around 600 mcg. If you’re breastfeeding, you’ll want around 500 mcg.

I'm a vegan. Can I get folate that's suitable for my lifestyle?

Many folate supplements, such as those in the form of methyl folate (L-5-MTHF), are available in vegan-friendly options. These supplements are often made with plant-based ingredients and are free from animal-derived products.