Best Vitamin K Supplements

Vitamin K is a fat-soluble nutrient best known for its role in normal blood clotting, bone health, and calcium regulation. Interest in vitamin K supplements (especially vitamin K2) has grown because vitamin K-dependent proteins help “direct” calcium into bone rather than letting it accumulate where it’s not wanted. However, vitamin K supplements vary significantly by form (K1 vs K2, and for K2: MK-7 vs MK-4), dose, and intended long-term use.

This guide reviews reliable vitamin K supplements available on Welzo via the Vitamins collection, focusing on clear labelling, trusted manufacturers, and how vitamin K is used in real routines. Where relevant, vitamin K is discussed alongside complementary nutrients found in Minerals and Vitamin D.

What Is Vitamin K?

Vitamin K is a family of fat-soluble compounds required to activate (carboxylate) specific proteins involved in blood clotting and calcium metabolism. It exists mainly as:

• Vitamin K1 (phylloquinone) — found mostly in leafy greens; primarily associated with clotting function.
• Vitamin K2 (menaquinones) — found in fermented foods and some animal foods; commonly used in supplements for bone and calcium-related routines.

Most supplements focus on vitamin K2, particularly MK-7, because it tends to stay active longer and suits once-daily dosing.

What Are Vitamin K Supplements Used For?

Vitamin K supplements are typically used to support normal blood clotting and to support calcium regulation over the long term, especially in routines focused on bone strength and healthy ageing. They are often added when dietary intake is inconsistent, when someone is building a bone-focused routine (commonly alongside vitamin D), or when a user specifically wants a vitamin K2 (MK-7) product to support vitamin-K-dependent proteins involved in bone and vascular calcium handling. Vitamin K supplements are not intended to treat disease; they are used to support normal physiological processes as part of diet and lifestyle.

Our Top Picks: Best Vitamin K Supplements

Best Overall Vitamin K2 (MK-7) Everyday Option

NOW Foods MK-7 Vitamin K-2 100 mcg (120 Veg Capsules)

Best Higher-Strength MK-7 for Experienced Users

Bio-Tech Pharmacal Vitamin K2 (MK-7) 150 mcg (100 Capsules)

Best Vitamin D3 + K2 Combination (Convenience Pick)

Vitamin D3 + K2 (120 Capsules) – Protocol for Life Balance

Best Budget-Friendly Vitamin K2 Entry Point

Swanson Vitamin K2 50 mcg (30 Softgels)

Detailed Product Reviews

1) NOW Foods MK-7 Vitamin K-2 100 mcg (120 Veg Capsules)

2) Bio-Tech Pharmacal Vitamin K2 (MK-7) 150 mcg (100 Capsules)

3) Vitamin D3 + K2 (120 Capsules) – Protocol for Life Balance

4) Swanson Vitamin K2 50 mcg (30 Softgels)

Comparison Table: Vitamin K Supplements at a Glance

Features and Benefits of Vitamin K Supplements

Key Features of High-Quality Vitamin K Supplements

High-quality vitamin K supplements prioritise clear form identification, precise microgram dosing, and suitability for long-term use. Because vitamin K is a fat-soluble nutrient, well-designed products are intended to be taken with food and avoid unnecessary fillers or proprietary blends that obscure the actual dose.

A key quality marker is whether the supplement clearly states vitamin K1 or vitamin K2, and for K2, whether it specifies the subtype (most commonly MK-7). MK-7 is widely preferred in supplements because it remains active in the body for longer, making it suitable for once-daily routines. Many high-quality vitamin K supplements are also designed to sit alongside other foundational nutrients, particularly vitamin D, as part of broader bone or general wellbeing strategies rather than being used in isolation.

Potential Benefits People Seek

From an evidence-led, clinician-reviewed perspective, people use vitamin K supplements to support normal blood clotting, bone health, and balanced calcium utilisation in the body. These benefits are not typically immediate; instead, they reflect vitamin K’s role in activating specific proteins that regulate essential physiological processes over time.

Vitamin K is commonly included in bone-focused and healthy ageing routines, especially in individuals with lower dietary intake of vitamin-K-rich foods or those already supplementing vitamin D. Because vitamin K works at the level of protein activation rather than stimulation, the benefits people seek tend to be gradual and supportive, becoming relevant with consistent, long-term use as part of an overall nutrition and lifestyle approach rather than as a short-term intervention.

How We Ranked These Vitamin K Supplements (Evaluation Criteria)

We ranked vitamin K supplements using criteria that matter for real-world use and long-term safety:

• Form clarity (non-negotiable): clear K1 vs K2 labelling, and for K2: MK subtype where applicable.
• Dose appropriateness: microgram-level dosing that fits daily use (not “mega-dose” marketing).
• Routine fit: once-daily usability and clear directions to take with food (fat-soluble vitamin).
• Label transparency: avoids vague proprietary blends that obscure actual vitamin K amount.
• Brand trust signals: manufacturers with broad adoption and consistent labelling standards.
• Value per effective dose: servings per pack relative to realistic daily use windows.

How We Evaluated These Vitamin K Supplements

We used a three-layer method: (1) evidence-led nutrition context (what vitamin K does and how it’s used), (2) product label review (form, dose, instructions), and (3) usability in real routines (whether it can realistically be taken consistently alongside common staples like vitamin D and magnesium).

This approach keeps the ranking grounded in how vitamin K supplements are actually used—conservatively, consistently, and as part of wider diet and lifestyle habits.

How to Take Vitamin K Supplements (Dosage, Timing & Best Practices)

Vitamin K is fat-soluble, so it’s typically best taken with a meal containing dietary fat. Consistency matters more than timing. Most people assess vitamin K routines over 8–12 weeks rather than expecting short-term “noticeable” effects.

• Start simple: choose one product and keep other changes minimal for 8–12 weeks.
• Avoid stacking: if a multivitamin includes vitamin K, account for it before adding more.
• If pairing with vitamin D: a combined D3+K2 product can be convenient, but separate products allow more dose control.
• Critical medication caution: if you use anticoagulants (e.g., warfarin), do not change vitamin K intake without medical supervision.

What Are the Signs of Vitamin K Deficiency?

Vitamin K deficiency is uncommon in healthy adults, and when it occurs, it’s usually linked to specific contexts such as fat-malabsorption conditions, certain medications, or prolonged very low intake. Because vitamin K is required for normal clotting protein activation, potential signs can include easy bruising, prolonged bleeding from cuts, frequent nosebleeds, or bleeding gums; however, these symptoms have many possible causes. If deficiency is suspected, medical evaluation is the appropriate route rather than self-diagnosis.

Is Vitamin K Safe? Side Effects & Interactions

Vitamin K is generally well tolerated at typical supplemental intakes. The most important safety issue is drug interaction—vitamin K can affect the action of vitamin K antagonist anticoagulants (such as warfarin). If you are on any blood-thinning medication, do not start, stop, or change vitamin K supplements without clinician guidance. As with other fat-soluble vitamins, avoid unnecessary high-dose stacking and periodically reassess your supplement routine.

External References & Scientific Sources

If you want to go deeper than supplement marketing, start with a nutrition authority that explains vitamin K forms (K1 vs K2), recommended intakes, dietary sources, and medication interactions in plain clinical language.

Link to check:
https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/

For a simpler overview, the consumer-facing fact sheet is useful for understanding what vitamin K does, where it’s found in food, and why anticoagulant users must keep intake consistent.

Link to check:
https://ods.od.nih.gov/factsheets/VitaminK-Consumer/

If you want a European risk-assessment lens, EFSA’s scientific opinion summarises how authorities evaluate vitamin K intake and safety considerations. This is particularly useful if you want “regulator style” context rather than influencer-style claims.

Link to check:
https://www.efsa.europa.eu/en/efsajournal/pub/4786

For bone-health context, a review paper can help explain why vitamin K is discussed alongside vitamin D and calcium, including mechanisms like osteocalcin activation. Reviews won’t prove a supplement “works for everyone,” but they’re a good way to understand the biological rationale and where evidence is stronger vs weaker.

Link to check:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452224/

Why You Can Trust Welzo

Welzo prioritises transparent labelling, evidence-led guidance, and trusted manufacturers. You can explore verified customer feedback via Welzo Reviews, and learn more about standards and quality through Welzo Staff, Ingredient Quality & Purity Certifications, and Supplement Quality Standards & Certifications.

FAQs: Vitamin K Supplements

Vitamin K1 vs K2: which should I choose?

K1 is most strongly linked to clotting function, while K2 is more commonly used in supplements for bone and calcium-related routines.

MK-4 vs MK-7: what’s the difference?

MK-7 generally stays active longer and is commonly used for once-daily supplements; MK-4 is shorter-acting and often dosed differently depending on the product.

Should vitamin K be taken with vitamin D?

Many people pair them because they’re both involved in calcium handling; you can use a combined product or separate products depending on how much dose control you want.

Can vitamin K interact with medications?

Yes—especially anticoagulants like warfarin. Don’t change vitamin K intake without clinical guidance if you take blood thinners.

How long does vitamin K take to “work”?

Vitamin K supports gradual physiological processes; most people assess routines over 8–12 weeks rather than expecting immediate effects.