Supporting your heart health is one of the most important long-term investments you can make for overall well-being. While diet, exercise, and medical care remain the foundation of cardiovascular health, certain supplements may help support cholesterol balance, blood pressure, circulation, and heart muscle function when used appropriately.
In recent years, interest in evidence-based nutrients such as Omega-3 supplements, CoQ10, and magnesium supplements has grown significantly — particularly among adults looking to proactively support heart health as they age or manage early cardiovascular risk factors.
This guide breaks down the best supplements for heart health in 2026, focusing on clinically researched nutrients and botanicals available on Welzo. We explain what each supplement does, who it’s best for, how it supports cardiovascular function, and how to use it safely, helping you make informed, practical decisions.
Heart health supplements are nutrients or plant-based compounds designed to support normal cardiovascular function. They are commonly used to help maintain:
Healthy cholesterol levels
Normal blood pressure
Efficient blood flow and circulation
Antioxidant protection for heart tissue
Some of the most commonly researched heart-supportive ingredients include plant sterols for cholesterol management, vitamin D supplements for vascular health, and traditional botanicals such as garlic supplements to support circulation.
It’s important to emphasise that supplements do not replace prescribed heart medications or lifestyle changes such as balanced nutrition, regular exercise, smoking cessation, and weight management. Instead, they act as supportive tools alongside medical guidance, particularly for people addressing nutritional gaps or early risk markers.
When used correctly and alongside a healthy lifestyle, heart health supplements can support several key aspects of cardiovascular wellbeing. While they are not treatments for heart disease, they may help maintain normal function and reduce strain on the cardiovascular system.
Supplements such as plant sterols and omega-3 fatty acids may help manage LDL (“bad”) cholesterol and triglyceride levels, which are important markers of cardiovascular risk.
Nutrients like magnesium, omega-3s, and garlic extract are associated with supporting normal blood pressure by aiding blood vessel relaxation and circulation.
The heart is one of the body’s most energy-demanding organs. Coenzyme Q10 (CoQ10) supports cellular energy (ATP) production, which may help maintain efficient heart muscle function.
Botanicals such as garlic extract and nutrients like omega-3s can help support circulation and vascular flexibility, contributing to overall cardiovascular efficiency.
Adequate vitamin D levels are associated with healthy blood vessel function, while antioxidants like CoQ10 help protect blood vessels from oxidative stress.
For people already following a balanced diet, exercising regularly, and managing stress, supplements can help fill nutritional gaps that may otherwise go unnoticed.
Best for Blood Pressure & Triglycerides: Omega-3 Fatty Acids
Best for Cholesterol Balance: Plant Sterols
Best for Heart Muscle & Cellular Energy: Coenzyme Q10 (CoQ10)
Best Mineral for Heart Rhythm & BP: Magnesium
Best for Vascular & Endothelial Support: Vitamin D3
Best Herbal Support for Circulation: Garlic Extract
Why selected:
A well-reviewed, popular omega-3 formula with high-quality EPA and DHA — the key forms associated with cardiovascular support.
Description:
The Lamberts Omega 3 Ultra Capsules Pack of 60 delivers concentrated omega-3 fatty acids that help support healthy triglyceride levels and normal blood pressure as part of a balanced lifestyle. EPA and DHA are essential fats the body cannot produce on its own, making supplementation beneficial for heart health when dietary intake is low.
Reviews:
Consistently popular with users for heart and circulatory support.
Price:
Available on Welzo
Where to buy:
Welzo
Pros:
• High-quality EPA & DHA blend
• Well-reviewed for cardiovascular support
• Easy daily dosing
Cons:
• Gradual effects — not instant
• Fish oil aftertaste possible
How to use:
Take 1–2 capsules daily with food.
Editor’s comment:
A strong foundational choice for long-term heart health.
Why selected:
One of the higher-concentration omega-3 products available at Welzo, offering a potent dose per serving for serious cardiovascular support.
Description:
The Carlson Labs Elite Omega‑3 Gems, 1600mg Natural Lemon uses a strong EPA/DHA profile in lemon-flavoured softgels that may be more pleasant for daily use. High potency makes it ideal for individuals aiming to support triglycerides and vascular health.
Reviews:
Highly rated for omega-3 potency and tolerability.
Price:
Available on Welzo
Where to buy:
Welzo
Pros:
• Higher dose per serving
• Pleasant taste
• Strong support for triglycerides
Cons:
• Potentially more expensive than basic formulas
• Best with meals
How to use:
Take as directed, usually 1 softgel per day with food.
Editor’s comment:
Great option if you want a more concentrated omega-3 dose without increasing capsule count.
Why selected:
A respected CoQ10 formula from a trusted brand, supporting cellular energy that’s helpful for heart muscle performance.
Description:
The Coenzyme Q10 (100 mg) 60 softgels - Nordic Naturals provides ubiquinone form CoQ10 in easily absorbed softgels. This nutrient aids mitochondrial energy production and carries antioxidant benefits that complement heart health-focused nutritional routines.
Reviews:
Well liked for its quality and consistent performance.
Price:
Available on Welzo
Where to buy:
Welzo
Pros:
• Trusted brand quality
• Supports energy production
• Suitable for long-term use
Cons:
• Not a quick fix — benefits build over time
• Best taken with food
How to use:
Take 1 softgel with a meal rich in healthy fats.
Editor’s comment:
A reliable CoQ10 choice for anyone over 40 or seeking deeper cellular support.
Why selected:
A generous supply of EPA and DHA at a great price point, ideal for everyday cardiovascular support.
Description:
The Omega Factors Wild Alaskan Salmon Oil 1000mg, 180 Softgels delivers triple-strength salmon oil in a high-count bottle, providing sustained omega-3 for blood lipid and heart health support.
Reviews:
Good value and consistent user satisfaction.
Price:
Available on Welzo
Where to buy:
Welzo
Pros:
• Excellent value
• Large supply per bottle
• Supports cardiovascular balance
Cons:
• May require multiple softgels daily
• Fish oil aftertaste for some
How to use:
Take 2 softgels daily with meals.
Editor’s comment:
Best choice if you want a cost-effective daily omega-3 product.
Why selected:
Liposomal delivery supports improved absorption and may suit people with sensitive digestion.
Description:
The LLO1 Liposomal Omega, 150ml - Lipolife uses advanced technology to protect omega-3 compounds and deliver them more efficiently, which can be helpful for users who struggle with traditional fish oil capsules.
Reviews:
Positive feedback for absorption and ease of use.
Price:
Available on Welzo
Where to buy:
Welzo
Pros:
• Better absorption than standard fish oil
• Gentle on digestion
• Suitable for daily use
Cons:
• Liquid format can be less convenient
• Typically more expensive
How to use:
Use as directed on the product label, usually measured in ml with meals.
Editor’s comment:
Best for people who want high omega-3 uptake without large capsules.
| Product | Best For | Key Benefit |
|---|---|---|
| Lamberts Omega 3 Ultra Capsules Pack of 60 | Overall Omega-3 Support | Balanced EPA/DHA support |
| Carlson Labs Elite Omega-3 Gems | High-Strength Heart Support | Potent EPA/DHA dose |
| Nordic Naturals Coenzyme Q10 100 mg 60 Softgels | Heart Muscle Energy | Cellular energy & antioxidant support |
| Omega Factors Wild Alaskan Salmon Oil 1000mg | Best Budget Omega | Excellent daily value |
| LLO1 Liposomal Omega 150ml | Enhanced Absorption | Advanced delivery for sensitive digestion |
Using supplements correctly is just as important as choosing the right ones. Below is practical guidance for each supplement featured in this guide.
How to use:
Take daily with meals for better absorption
Typical doses range from 250–1000 mg combined EPA/DHA (follow product label or medical advice)
Best time to take:
With your main meal of the day
Tip:
Consistency matters more than high doses
How to use:
Take with meals containing fat
Most studies use 1.5–2.4 g per day, divided across meals
Best time to take:
With breakfast or lunch
Tip:
Works best alongside a cholesterol-conscious diet
How to use:
Take once or twice daily
Always take with food (fat improves absorption)
Best time to take:
Morning or lunchtime
Tip:
Benefits build gradually over several weeks
How to use:
Take daily, following label instructions
Forms like magnesium glycinate or citrate are often better tolerated
Best time to take:
Evening or before bed (may support relaxation)
Tip:
Avoid very high doses unless advised by a healthcare professional
How to use:
Take daily, especially during autumn and winter in the UK
Typical maintenance doses range from 400–2000 IU (check label)
Best time to take:
With a meal containing fat
Tip:
A blood test can confirm if supplementation is needed
How to use:
Take once or twice daily with meals
Use standardised extracts for consistent dosing
Best time to take:
With food to reduce stomach upset
Tip:
Speak to a doctor if you take blood-thinning medication
Heart supplements are formulated to support cardiovascular function by addressing key systems involved in heart health, including circulation, blood vessel integrity, cellular energy production, and cardiac muscle performance. In dogs (and humans), the heart works continuously to pump blood, deliver oxygen and nutrients, and remove waste products. Over time, age, genetics, breed predisposition, and lifestyle factors can place additional strain on the cardiovascular system.
Heart supplements work by supporting these underlying biological processes rather than treating acute disease, making them most effective as part of a long-term health strategy.
The heart is a muscle that requires a constant supply of energy to function efficiently. Ingredients such as coenzyme Q10 (CoQ10), taurine, and L-carnitine play important roles in cellular energy production within heart muscle cells. These nutrients support mitochondrial function, helping cardiac cells generate the energy needed for sustained, rhythmic contractions.
Certain heart supplements contain nutrients that help support healthy blood flow and circulation. Omega-3 fatty acids, hawthorn berry, and magnesium contribute to blood vessel relaxation and flexibility, allowing blood to move more efficiently through the cardiovascular system. Improved circulation reduces workload on the heart and supports oxygen delivery throughout the body.
Minerals such as potassium and magnesium help regulate fluid balance and nerve signalling, both of which influence blood pressure. By supporting normal vascular tone and electrolyte balance, heart supplements can help maintain blood pressure within a healthy range, particularly in ageing individuals or breeds prone to cardiovascular strain.
The heart is highly metabolically active and therefore vulnerable to oxidative stress. Antioxidants such as vitamin E, vitamin C, selenium, and plant compounds help neutralise free radicals that can damage heart cells over time. Reducing oxidative stress supports long-term cardiovascular resilience and tissue health.
Proper heart rhythm depends on precise electrical signalling within cardiac tissue. Nutrients like taurine and magnesium support this signalling process, helping maintain a steady and coordinated heartbeat. This is particularly important for dogs or individuals with known rhythm sensitivities or breed-related risks.
Heart supplements are designed for ongoing cardiovascular support, not immediate symptom relief. Their benefits build gradually as nutrient levels stabilise and cellular processes are supported. Consistent daily use over weeks or months is typically required to see meaningful improvements in energy levels, endurance, and overall cardiovascular function.
Heart supplements are most effective when used proactively, especially for senior individuals, larger dog breeds, or those with a family history of heart conditions. While they do not replace veterinary care or prescribed medication, they can play a valuable role in supporting heart health alongside a balanced diet and appropriate medical supervision.
In many cases, yes, but combinations should be sensible:
Omega-3 + CoQ10 → commonly paired for heart support
Magnesium + Vitamin D → often complementary
Plant sterols → should be timed with meals
However, if you:
Take prescription heart medication
Have a diagnosed heart condition
Take blood thinners
You should always consult a healthcare professional before combining supplements.
Each supplement was assessed based on:
Clinical relevance to heart health markers (cholesterol, blood pressure, circulation)
Scientific evidence from the UK and international health organisations
Safety and suitability for long-term use
Practical benefit for everyday users
Availability within the Welzo catalogue
Guidance from the NHS and British Heart Foundation was used to ensure alignment with UK cardiovascular health advice.
NHS – Prevention of heart disease
Provides UK-focused clinical guidance on lifestyle and cardiovascular risk management.
https://www.nhs.uk/conditions/heart-attack/prevention/
British Heart Foundation – Supplements & Heart Health
Explains the role (and limitations) of supplementation alongside diet and medication.
https://www.bhf.org.uk/informationsupport/heart-matters-magazine/nutrition/ask-the-expert/supplements
NHS – Fatigue, Blood Pressure & Cardiovascular Symptoms
Context around general cardiovascular symptoms and risk factors.
https://www.nhs.uk/conditions/fatigue/
Harvard Health – Omega-3 Fatty Acids & the Heart
Discusses how omega-3s support heart health (blood pressure, triglycerides) and the limits of current evidence.
https://www.health.harvard.edu/blog/omega-3-fatty-acids-and-the-heart-new-evidence-more-questions-2021032422213
NHS – High Cholesterol Overview (inc. diet & nutrient support)
Covers risk factors for high cholesterol and lifestyle management including diet and sterols.
https://www.nhs.uk/conditions/high-cholesterol/
American Heart Association – Plant Sterols
A well-cited overview (international) on how plant stanols/sterols can help support cholesterol.
https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/fats/plant-sterols
British Heart Foundation – CoQ10
Explains CoQ10’s role and the current evidence status in heart health.
https://www.bhf.org.uk/informationsupport/heart-matters-magazine/nutrition/ask-the-expert/coq10
WebMD – Coenzyme Q10 Health Overview
Clinical summary of CoQ10, including heart and cellular energy support.
https://www.webmd.com/vitamins-and-supplements/supplements-heart-healthy
NHS – Magnesium & Nutrient Overview
Explains the role of magnesium in health and why it’s often supplemented.
https://www.nhs.uk/conditions/vitamins-and-minerals/magnesium/
NIH – Magnesium Fact Sheet for Health Professionals
Comprehensive clinical resource on magnesium’s role in the body, including heart muscle and nerve function.
https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
NHS – Vitamin D
Explains vitamin D’s roles and why many UK adults are deficient; relevant to cardiovascular considerations.
https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/
NIH – Vitamin D Fact Sheet for Health Professionals
Clinical review of vitamin D’s functions and evidence.
https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
WebMD – Garlic Health Effects
Overview of garlic supplements and their potential roles in circulation and cardiovascular markers.
https://www.webmd.com/vitamins-and-supplements/supplements-garlic
Mayo Clinic – Garlic Supplements Safety
Discussion of garlic’s uses and interactions, particularly with blood-thinning medications.
https://www.mayoclinic.org/drugs-supplements-garlic/art-20362258
PubMed – Adaptogens & Stress Response (including cardiovascular implications)
Peer-reviewed research on how adaptogenic herbs may support stress pathways relevant to heart health.
https://pubmed.ncbi.nlm.nih.gov/17381239/
Heart health supplements should be used responsibly. Some supplements — particularly omega-3s and garlic — may interact with blood-thinning or blood pressure medications. Always consult a healthcare professional before starting supplements, especially if you have a diagnosed heart condition or take prescription medication.
No. Supplements support heart health markers but do not replace medication, diet, or lifestyle changes.
Plant sterols are among the most studied supplements for supporting healthy LDL cholesterol.
They are generally safe but may not be suitable for everyone, particularly at high doses or with certain heart conditions.
No. Supplements should only be used alongside medical advice, not as replacements.
This depends on individual needs and medications — combining supplements should be discussed with a healthcare professional.
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