SAMe from Jarrow Formulas delivers mood, joint and liver support, making it a reliable everyday pick thanks to enteric coating and a vegan allergen free formulation.

Benefits & Features:

• SAMe drives mood balance by boosting neurotransmitter production.
• Supports joint comfort by helping cartilage upkeep.
• Methylation support helps energy and resilience from the inside, with SAMe powering the process.
• Enteric coating shields SAMe from stomach acid, aiding targeted absorption.
• Produced under controlled low humidity conditions and blister packed, this vegan and gluten free formula keeps potency steady for daily use, helping maintain potency through its shelf life.

Jarrow Formulas has a long standing reputation for science led supplements, and SAMe is built with care. EnteroGuard coating protects the active SAMe from stomach acid, ensuring delivery to where absorption matters. The product is produced under controlled low humidity and blister packed to keep potency intact. NIH notes methylation is central to energy production, joint health and liver function, and this formula supports that process in an everyday vegan allergen free way. It fits well with probiotics in a balanced wellness routine and is not a vitamin d supplement.

S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate)

• GTIN: 790011200147
• Manufacturer: Jarrow Formulas
• Size: 20 tablets
• Categories: Jarrow Formulas
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health care consultant. Store in a cool, dry place. Do not use if you are pregnant, nursing, or taking prescribed medications such as antidepressants, including SSRIs and MAO inhibitors, without consulting a physician. Individuals with Parkinson’s disease, bipolar disorder, or manic depression should not use SAMe.

Please consult the product packaging for accurate instructions on how to use the product.

*Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

The Active Ingredient Is: S-Adenosyl Methionine (SAMe)

S-Adenosyl Methionine, or SAMe, is a natural compound involved in the body’s methylation processes which support energy production and essential biochemical reactions.

This formula uses enteric-coated SAMe to aid delivery to the intestines, maximising stability and bioavailability while remaining vegan and free from major allergens.

What Does S-Adenosyl Methionine Do?

SAMe participates in methylation, a fundamental cellular mechanism that supports normal metabolic function and contributes to the production of important biomolecules. NHS and EFSA notes recognise SAMe as a methyl donor integral to multiple body systems.

Within healthy physiology, SAMe contributes to joint and liver support through its role in cellular processes and energy production, with the enteric coating helping absorption where needed most.

This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Jarrow Formulas brings a science‑led, thorough approach to SAMe supplementation, which is why we picked them as our reliable supplier for SAMe products. This brand’s long-standing focus on thoughtful formulation and potency lines up with our commitment to evidence‑based curation, making Jarrow Formulas a natural fit for Welzo shoppers seeking reliable methylation support from a well‑established name in the field. Their reputation for rigorous formulation and quality manufacturing underpins the product you see today. For our crew, the focus on tight production controls and targeted delivery via enteric coating shows a clear commitment to keeping potency and absorption, key factors when choosing SAMe products. Their vegan, gluten‑free, and major allergen‑free listing further backs Welzo’s quality standards. This brand was assessed by our team of medical experts for compliance with the standards we enforce, ensuring alignment with our vetting criteria.

Welzo’s brand evaluation process focuses on history, manufacturing integrity, and reliability, and Jarrow Formulas consistently hits those standards. This product is a great fit for a brand that's known for purity, controlled manufacturing, and transparent formulation, making Jarrow Formulas the preferred SAMe partner in our range.