SHGB (Sex Hormone Binding Globulin) Blood Test
SHGB (Hormone Binding Globulin) Blood Test is used to measure the levels of SHBG in the blood. It can be used to help diagnose conditions such as hirsutism (excessive hair growth), hypogonadism (low testosterone levels), and polycystic ovary syndrome (PCOS).
- SHGB (Sex Hormone Binding Globulin) Blood Test
- Biomarkers
- Information
SHGB (Sex Hormone Binding Globulin)
High levels of SHBG may be seen in conditions associated with increased oestrogen levels, such as pregnancy, cirrhosis, and certain types of tumours. Low levels of SHBG may be seen in conditions associated with decreased oestrogen levels, such as menopause, androgen excess, and obesity.
The SHGB test is used to help diagnose conditions associated with abnormal levels of testosterone or oestrogen. It may also be used to monitor treatment for these conditions.
Symptoms of Low SHGB
Symptoms of low SHBG levels may include:
Weight gain
Depression
Irritability
Muscle weakness
Bone loss
Hot flashes
Fatigue
Additional Information
SHBG is a protein produced by the liver. It binds to three sex hormones: testosterone, dihydrotestosterone (DHT), and oestradiol. These hormones are then carried in the blood to their target tissues.
SHBG levels can be affected by a number of factors, including age, gender, liver disease, obesity, and certain medications. A high SHBG level can lower the amount of active hormone available to bind to receptors, while a low SHBG level can increase the amount of active hormone available.
SHBG levels can also be affected by certain medications, such as Androgen Deprivation Therapy (ADT) for prostate cancer, oestrogen replacement therapy, and some oral contraceptives. If you are taking any of these medications, please inform your doctor prior to having this test done.
The SHBG blood test is a simple and quick way to measure the levels of SHBG in your blood. It is a safe and reliable test that can be used to help diagnose conditions such as hirsutism, hypogonadism, and PCOS. If you are taking any medications that may affect your SHBG levels, please inform your doctor prior to having this test done.
Symptoms of High SHGB
Symptoms of high SHGB:
- Breast enlargement
- Decreased sex drive
- Infertility
- Cushing's disease
- Obesity
- Polycystic ovary syndrome (PCOS)
- Acromegaly
Why take a test?
The SHBG blood test is an effective way to measure the SHBG in your blood. The results from this safe and reliable test will be helpful to diagnose conditions such as hirsutism, hypogonadism and PCOS.










Experts Opinion on SHGB Blood Tests
"SHBG is a protein that binds to most sex hormones, however, when these hormones are bound, it means the body cannot use them. We measure the SHBG levels in the blood to determine if hormone levels are at an optimum level."

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