Methyl Factors is a methyl donor driven supplement that supports methylation and helps maintain healthy homocysteine levels, promoting brain and heart wellness. Bioactive forms like L-methylfolate and methylcobalamin fuel effective methylation. Cytoplan's plant based, vegetarian friendly formula mirrors our commitment to quality and transparency. This makes it a convenient daily companion for busy lifestyles.

Available Sizes & Variants:

60 capsules – convenient monthly supply.

Benefits & Features:

• Supports healthy methylation and homocysteine balance.
• Powerful blend uses bioactive L-methylfolate and methylcobalamin to support mood, cognition, and nervous system function, with added betaine for cardiovascular balance and cellular energy too.
• Intended for daily use, designed with allergens avoided and plant based capsules.
• Vegetarian and vegan friendly, non GMO and dairy-free to fit a wide range of diets.
• Quality you can feel, supported by transparent sourcing and rigorous testing.

Cytoplan has built its reputation on vegetarian, vegan friendly formulas with non-GMO ingredients and allergen avoidance, and Methyl Factors stays true to that ethos. The formula uses bioactive L-methylfolate and methylcobalamin for maximum absorption, paired with betaine to support homocysteine balance. Plant-based capsules fit Cytoplan's transparency-led approach to sourcing and manufacturing. It's designed with common genetic variations in mind, offering practical methyl donor support that can slot into a daily routine quickly and easily. For a well rounded routine, many customers pair methyl donor support with other supplements like magnesium glycinate, a vitamin d supplement or MSM.

Trimethylglycine (TMG, also known as Betaine), vitamin B12 as methylcobablamin, vitamin B6 as pyridoxal-5-phosphate, zinc citrate, vitamin B2 as riboflavin 5-phosphate, methylfolate, Vegetable Cellulose (Capsule shell).

• GTIN: 5060202184828
• Manufacturer: Cytoplan
• Categories: Best SellersNew ArrivalsSubscribe & Save Products
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1 capsule daily or as directed by your practitioner. Take 1 capsule daily with food or as directed by a healthcare professional.

Please consult the product packaging for accurate instructions on how to use the product.

The Key Ingredient Is: Vitamin B12 (Methylcobalamin)

Vitamin B12 in the methylcobalamin form is a water-soluble vitamin vital for normal metabolic and neurological function.

This bioactive form is easily utilised by the body and is picked for its high bioavailability and suitability for people with common genetic variations.

What Vitamin B12 Does?

Vitamin B12 helps maintain normal energy metabolism and supports the nervous system and cognitive function.

It also helps keep normal homocysteine metabolism as part of broader B‑vitamin interactions important for overall health.

This supplement is not meant to diagnose, treat, cure, or prevent any disease.

When selecting a supplier for methyl donor support, Cytoplan stood out against competitors for their clear commitment to safety, sustainability and accessibility. This brand is recognised for ethically sourced, non-GMO ingredients and plant-based capsules, with a strong emphasis on vegetarian and vegan suitability. Their transparent approach to ingredient selection aligns with our aim to partner with manufacturers that prioritise quality from the ground up, supported by our rigorous testing protocols.

Cytoplan has built a credible reputation for focusing on quality manufacturing and safety, with a heritage centred on responsible product development and consumer trust. Their emphasis on bioactive, highly absorbable forms in their formulations reflects a science-led philosophy that resonates with Welzo’s standards and our medical team’s expectations, as examined by our team of medical experts.

This brand and product pairing specifically fits our methylation-focused criteria, combining TMG with active B vitamins and methylated folate forms in a way that supports safe, well-tolerated supplementation. The decision to partner with Cytoplan reflects our rigorous internal evaluation process and a belief in lasting quality, safety and integrity.