SAMe is a dietary supplement that helps mood balance and joint comfort, powered by the key active SAMe ingredient and backed by Now Foods' trusted U.S. quality standards. Now Foods is proudly manufactured in the USA under GMP standards to maintain purity and consistency. This formulation is vegetarian and free from common allergens, making it easy to fit into everyday wellness routines.

Available Sizes & Variants:

60 tablets SAMe - Great value for a month's supply and easy daily use.

Benefits & Features:

• Supports mood balance.
• Key sam e supports neurotransmitter synthesis for steadier mood.
• Supports joint comfort after activity.
• Manufactured in the USA to GMP standards.
• Regular use of sam e may help support mood and daily function, supporting a sense of balance that helps you get through busy days, workouts, and everyday stresses.

Now Foods has built a lasting reputation for quality and trust. This SAMe supplement is proudly made in the USA under GMP standards and is NPA-certified, with testing to ensure consistent potency. The brand's commitment to allergen free formulas means it's dairy free, gluten free and vegetarian friendly. The wellness range also includes a vitamin d supplement and probiotics, reflecting a holistic approach to daily health and balance across mind and body.

SAMe (S-Adenosyl-L-Methionine), Microcrystalline cellulose, enteric coating (methacrylic acid, hypromellose, calcium carbonate, hydroxypropyl cellulose, glycerin), croscarmellose sodium, magnesium stearate (vegetable source), silicon dioxide, stearic acid (vegetable source), ascorbic acid and citric acid.
Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

• GTIN: 733739001412
• Manufacturer: Now Foods
• Categories: CHECKOUT UPSELLNew ArrivalsNOW Foods
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1 tablet 2 to 4 times daily, ideally on an empty stomach. Recommended to refrigerate after opening. Adults\, as a dietary supplement\, take one (1) capsule daily with a meal.

Please consult the product packaging for accurate instructions on how to use the product.

The Active Ingredient Is: S-Adenosyl-L-Methionine (SAMe) Disulfate Tosylate

S-Adenosyl-L-Methionine, or SAMe, is a naturally occurring compound important for normal nervous system function and general metabolism.

This form is derived from S-Adenosyl-L-Methionine Disulfate Tosylate and appears as the active ingredient in this product, with other non-active ingredients used for formulation and stability.

What Does S-Adenosyl-L-Methionine (SAMe) Do?

SAMe is involved in neurotransmitter synthesis and has been studied for mood support and joint health, contributing to normal nervous system function and comfort after physical activity.

EFSA-style understanding supports its role in these normal physiological processes, with broader research exploring potential mood-related and joint health benefits.

This product is not intended to diagnose, treat, cure, or prevent any disease. *This product is not intended to diagnose, treat, cure, or prevent any disease.

Welzo’s partner selection starts with a rigorous bar for brand credibility, heritage and manufacturing excellence. Now Foods, a well established U.S. manufacturer, is recognised for its commitment to quality within the supplement industry and operates under GMP frameworks verified by the National Products Association. This solid base, coupled with their openness about sourcing and production, helps us feel assured in a reliable supply chain. Our expert team of doctors, nurses, and nutritionists our expert team of doctors, nurses, and nutritionists evaluates brands like Now Foods for safety, consistency and practice-wide quality, feeding into our trusted vetting process.

The Now Foods ethos emphasises producing to high standards and doing routine stability and potency testing under GMP guidelines, with products made in the USA from globally sourced ingredients. This lines up with our commitment to rigorous quality certification through our quality certification process, ensuring reliability for customers seeking SAMe. The brand is recognised for its role in supporting nervous system health and joint comfort, based on available research context.

This brand-to-product match is ideal for SAMe, where Now Foods’ quality framework supports the product’s intended use while reflecting Welzo’s criteria for brand credibility, testing integrity and lifecycle consistency.