Nytol Original Tablets are clinically proven nighttime sleeping aids containing diphenhydramine as the active ingredient. They provide temporary relief from sleeplessness and ensure a restful and faster sleep. They have diphenhydramine hydrochloride, which reduces nighttime restlessness and ensures an uninterrupted sleep cycle.

Research backs it up. A study published by Cureus in 2021 found that diphenhydramine hydrochloride is effective as an OTC sleep aid and is very popular in Saudi Arabia. It is suitable for those who struggle with occasional sleepiness. It is very effective for a healthy sleep pattern and ensures a trusted nighttime remedy and a fresh wake-up in the morning.

Features and benefits of Nytol Original Tablets

• It has a clinically proven formula and has diphenhydramine, a hypnotic agent promoting quick sleep and relaxation. 
• It relieves temporary insomnia and improves sleep quality for a refreshed morning. 
• It starts working within 30-60 minutes and ensures an easy recovery from sleeplessness.
• It is suitable for occasional use, non-habit-forming, and a reliable and safe sleep aid.
• It is available in an easy-to-take pack of 20 tablets, suitable for on-the-go or home use. 

The active substance: Each tablet contains Diphenhydramine Hydrochloride 25mg.The other ingredients are: Anhydrous Lactose, Microcrystalline Cellulose, Maize Starch, Stearic Acid and Silicon Dioxide.

Welzo is not liable for discrepancies on the website. Check product packaging for exact information.

UK, Europe & Rest of the World Shipping Details:
Same day dispatch for orders placed by 2pm (Orders after 2pm dispatched next working day).

Free shipping on orders over £50 to the UK.

Returns: Our supplements are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 14 days in the same original and unopened packaging.

1-2 tablets 30-60 minutes before bedtime.

Welzo is not liable for allergen information. Always follow the directions/ingredients on the product packaging to ensure proper use.

Nytol is contraindicated in patients who are hypersensitive to diphenhydramine or any of the excipients and in those with the following conditions: stenosing peptic ulcer, pyloroduodenal obstruction.

Nytol should be used with caution in patients with myasthenia gravis, epilepsy or seizure disorders, narrow-angle glaucoma, prostatic hypertrophy, urinary retention, asthma, bronchitis and chronic obstructive pulmonary disease (COPD), moderate to severe hepatic impairment and moderate to severe renal impairment.

Tolerance may develop with continuous use. Seek medical advice if sleeplessness persists, as insomnia may be a symptom of serious underlying medical illness.

May increase the effects of alcohol, therefore alcohol should be avoided.

Avoid use of other antihistamine-containing preparations, including topical antihistamines and cough and cold medicines.

Use with caution in the elderly, who are more likely to experience adverse effects. Avoid use in elderly patients with confusion.

Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Keep out of the reach and sight of children.

Diphenhydramine may potentiate the sedative effects of alcohol and other CNS depressants (e.g. tranquillizers, hypnotics and anxiolytics).

Monoamine oxidase inhibitors(MAOI) prolong and intensify the anticholinergic effects of diphenhydramine. The product should be used with caution with MAOIs or within 2 weeks of stopping an MAOI.

As diphenhydramine has some antimuscarinic activity, the effects of some anticholinergic drugs (e.g. atropine, tricyclic antidepressants) may be potentiated therefore medical advice should be sought before taking diphenhydramine with such medicines.

Diphenhydramine is an inhibitor of the cytochrome p450 isoenzyme CYP2D6. Therefore, there may be a potential for interaction with drugs which are primarily metabolised by CYP2D6, such as metoprolol and venlafaxine.

Diphenhydramine should not be used in patients receiving any of the above drugs unless directed by a doctor.

Pregnancy
Diphenhydramine crosses the placenta. Because animal reproduction studies are not always predictive of human response and since there is inadequate experience with use of diphenhydramine in pregnant women, the potential risk for humans is unknown. Use of sedating antihistamines during the third trimester may result in reactions in the newborn or premature neonates. This drug is not recommended during pregnancy. Consult a doctor before use.

Lactation
Diphenhydramine has been detected in breast milk, but the effect of this on breastfed infants is unknown. Nytol is not recommended for use during lactation. Consult a doctor before use.

Nytol is a hypnotic and will produce drowsiness or sedation soon after the dose has been taken. It may also cause dizziness, blurred vision, cognitive and psychomotor impairment. These can seriously affect the patient's ability to drive and use machines. If affected, do not drive or operate machinery.

Overdose is likely to result in effects similar to those listed under adverse reactions. Additional symptoms may include mydriasis, fever, flushing, agitation, tremor, dystonic reactions, hallucinations and ECG changes. Large overdose may cause rhabdomyolysis, convulsions, delirium, toxic psychosis, arrhythmias, coma and cardiovascular collapse.

Treatment should be supportive and directed towards specific symptoms. Convulsions and marked CNS stimulation should be treated with parenteral diazepam.

Nytol Original Tablets PIL