TMG with Folinic Acid and Methyl B12 is a methylation support supplement that helps keep healthy homocysteine levels and support cardiovascular and nervous system wellness. The key active ingredients TMG, folinic acid and methyl B12 work together to support methylation and blood chemistry. The brand, Kirkman Laboratories, is known for ultra tested and allergen-free manufacturing, delivering high quality plant based capsules you can trust.

Available Sizes & Variants:

120 capsules - Daily capsules for ongoing methylation support.

Benefits & Features:

• Supports healthy homocysteine levels as a tmg supplement for daily wellbeing.
• A strong methylation boost comes from 500mg TMG per capsule, combined with folinic acid and methylcobalamin to support methylation, helping the body convert homocysteine into beneficial compounds.
• Hypoallergenic plant based capsules keep sensitivities in mind.
• Intended for daily use to support long term methylation health and vitamin b12 supplements intake.
• Methyl B12 in methylcobalamin supports red blood cell formation, nerve function and DNA synthesis, helping you feel steadier through daily tasks.

Drawing on Kirkman Laboratories' careful, allergen aware approach, this TMG formula pairs 500mg TMG with folinic acid and methyl B12 in plant based capsules. The blend is designed so folate is available to support TMG's work in the body, helping homocysteine metabolism. The brand's Ultra Tested, cGMP compliant manufacturing and strict allergen exclusions help deliver a product you can trust, without common triggers for sensitivities. Made with vegetarian ingredients and a commitment to quality, it's built for everyday methylation support.

Trimethylglycine, di-calcium phosphate, calcium folinate, magnesium stearate (vegetable), methylcobalamin, plant cellulose capsule.

• GTIN: 812325021123
• Manufacturer: Kirkman Laboratories
• Categories: KirkmanNew ArrivalsPopular Supplement BrandsVitamin B12 (Cobalamin) Supplements & Tablets
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take one to two capsules daily or as instructed. Take 2 vegetarian capsules daily or as directed by a qualified health care professional.

Please consult the product packaging for accurate instructions on how to use the product.

1. TMG with Folinic Acid and Methyl B12 is a powerful combination that provides essential nutrients for optimal health and wellness. This product contains 500mg of TMG, also known as trimethylglycine, which is a natural compound found in many foods and known for its ability to support cardiovascular health.
2. The addition of Folinic Acid and Methyl B12 to this supplement provides additional benefits for the body, including improved energy levels, enhanced cognitive function, and better nerve function. These nutrients work together to support overall health and wellbeing, making this product an excellent addition to any daily supplement routine.

The Active Ingredient Is: Trimethylglycine (TMG)

Trimethylglycine, often called TMG or betaine, is a nutrient that acts as a methyl donor in body processes. It plays a role in normal metabolic processes and is included here as the primary active ingredient.

This form is paired with folinic acid and methyl B12 to support methylation-related functions and blood chemistry while being delivered in plant-based capsules.

What Does Trimethylglycine Do?

TMG functions as a methyl donor involved in converting homocysteine to methionine, a process linked with normal cardiovascular and liver function. Research indicates higher TMG intake has been associated with lower inflammatory markers and with lower blood pressure measurements in some populations.

These effects relate to the nutrient’s role in methylation and related metabolic pathways, within the context of EFSA- and NHS-aligned understanding of normal physiology.

This supplement is not intended to diagnose, treat, cure, or prevent any disease.

Kirkman Laboratories stands out for Welzo as a collaborator that prioritises quality, safety and approachable formulation principles. This brand upholds stringent quality standards and operates under cGMP manufacturing practices, underscoring a consistent commitment to product integrity across its range. Their hypoallergenic approach and commitment to allergen-free formulations align with Welzo’s focus on safe, broad access supplements, while plant-based capsules and excipients reinforce vegan/vegetarian compliance that resonates with wide consumer needs.

The brand’s Ultra Tested stance reinforces a methodical quality mindset, and Kirkman’s clear emphasis on controlled ingredients supports our requirement for dependable composition. Our vetting process recognised these strengths, alongside an open production philosophy, which we capture for customers via our ingredient quality and purity standards.

This brand and product pairing is especially well suited for methylation-support formulations like TMG with Folinic Acid and Methyl B12, reinforcing Welzo’s aim to connect expert curation with reliable manufacturing. For further context on our team’s assessment, see our expert team of doctors, nurses, and nutritionists.