The 9 Best B12 Supplements of 2025

Vitamin B12, or cobalamin, is a nutrient responsible for energy metabolism, red blood cell synthesis, healthy neurological function and DNA synthesis. It is present in many animal-based foods, particularly salmon, beef, dairy products and fortified foods.

Small amounts of B12 are present in mushrooms and algae, but plant-based foods are generally deficient in B12. Therefore, people following vegan diets, taking medications that reduce the absorption of vitamins and older adults are at risk of developing B12 deficiencies. According to the National Institute of Health, 12% of women of childbearing age in the UK experience B12 deficiency.

This article discusses the nine best B12 supplements in the UK marketplace. It highlights their essential information, e.g., form, dose of B12, % daily value provided, pros and cons, and the main reason for choosing them. For better help, consult the healthcare provider for better-personalised advice.

Daily B12 requirements 

The recommended daily intake (RDI) of B12 depends upon age and health status. Likewise, pregnant and breastfeeding women need more B12 than others. The RDI of B12 is 2.4 mcg/day. 

This requirement is higher in people diagnosed with vitamin deficiencies and severe signs. Another good news is that vitamin B12 is water soluble, and the body doesn't store the excess amount. So, higher amounts are not to be worried about and are safe. However, it is better to stay within prescribed doses to save money on unnecessarily higher doses.

How to choose the best B12 supplement? 

If a person is diagnosed with B12 deficiency and supplementation is recommended, many factors must be considered before choosing the right supplement. These factors are; 

Form of supplement

Various forms of B12 supplements available in the market are tablets, capsules, gummies, sprays, lozenges, liquids, and chewable tablets. A person must choose the best-tolerated and best-liked product.  

Quality 

The essential criteria of a high-quality product are the accuracy of the label, third-party testing and testing for heavy metals and other contaminants. Choose the product that has the maximum accreditations and certifications.  

Dose 

Consult the healthcare provider about the desired dose and choose the supplement accordingly. 

Price tag

The price per serving is different for different products. Choose a product that best suits your budget. 

Forms of B12 present 

The supplements contain various forms of B12, e.g., methylcobalamin, cyanocobalamin, adenosylcobalamin and hydroxocobalamin. The most common form used in the supplements is cyanocobalamin. However, all types have similar absorption and effectiveness. Consult the doctor as some forms are better suited to treat certain health conditions.

Products Summary

Best overall: Lamberts Vitamin B12 Tablets

Product specifications 

Price & availability: £9.54 (buy Lamberts Vitamin B12 Tablets at Welzo)

Packing size: 60 tablets

Form: Tablets

Dose of B12: 1000 μg 

Vegan friendly: Yes

Serving size: 1 pill per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 56 reviews at Welzo)

Why do we choose it?: The high-strength vitamin B12 supplement is a game-changer for vegetarians, vegans, and older people. With 1000µg per tablet, you conveniently get this vital nutrient. It supports red blood cell production, immune function, and energy metabolism. The small, easy-to-swallow tablets make daily supplementation hassle-free. 

Made in the UK to GMP pharmaceutical standards, it's a quality product one must trust. However, remember that while supplements are beneficial, they must complement a balanced diet, not replace it.

Best for neurological health: Pure Encapsulations Adenosyl/ Hydroxy B12 Capsules

Product specifications 

Price & availability: £27.77 (buy Pure Encapsulations Adenosyl/ Hydroxy B12 Capsules at Welzo)

Packing size: 90 capsules

Form: Capsules 

Dose 0f B12: 2,000 mcg

Vegan friendly: Yes

Serving size: 1 capsules per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 108 reviews at Welzo)

Why do we choose it?: Pure Encapsulations' Adenosyl/Hydroxy B12 90 Capsules offer a potent blend of adenosylcobalamin and hydroxocobalamin, providing comprehensive mitochondrial support. This formula is tailored to enhance neurological health, nerve cell function, and the synthesis of neuronal myelin. It converts carbohydrates into energy efficiently by aiding energy metabolism and cellular health. As a pure and vegan-friendly supplement, it's free from GMOs, gluten, and common allergens. 

Take one capsule 1-3 times daily with meals for optimal benefits—Trust Pure Encapsulations for quality, with no artificial additives or unnecessary ingredients. Elevate your wellness with Adenosyl/Hydroxy B12 90 Capsules.

Quick absorbing formula: Klaire Labs B12 Liquid (Methylcobalamin) 5mg

Product specifications 

Price & availability: £31.95 (buy Klaire Labs B12 Liquid (Methylcobalamin) 5mg) at Welzo)

Packing size: 120ml

Form: Liquid 

Dose of B12: 5mg

Vegan friendly: Yes

Serving size: 1 drop per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 106 reviews at Welzo)

Why do we choose it?: Klaire Labs' B12 Liquid (Methylcobalamin) 5mg is a game-changer in vitamin B12 supplementation. Offering the active form of B12 in a convenient liquid format ensures rapid and efficient absorption for maximum benefit. With a potent dose of 5 mg (5000 mcg) of methylcobalamin per dropper, it's an excellent choice for those seeking to support red blood cell function and regulate homocysteine levels. Its commitment to purity sets it apart; free from common allergens and artificial additives, it's a safe option for many. 

Trusted by healthcare practitioners for over 50 years, Klaire Labs delivers yet another quality product developed in close collaboration with physicians. Elevate your wellness journey with B12 Liquid (Methylcobalamin) and experience the difference firsthand.

Best for vegans: HealthAid Vitamin B12 (1000 mcg) Tablets

Product specifications 

Price & availability: £14.63 (buy HealthAid Vitamin B12 (1000 mcg) Tablets at Welzo)

Packing size: 100 tablets

Form: Tablets

Dose of B12: 1000 mcg 

Vegan friendly: Yes

Serving size: 1-2 tablets per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 100 reviews at Welzo)

Why do we choose it?: HealthAid's Vitamin B12 1000 mcg Tablets are a reliable source of this vital nutrient, essential for various bodily functions. Each tablet delivers a potent 1000 mcg dose, surpassing the daily recommended intake for most adults. Vitamin B12 is pivotal in maintaining nerve health, supporting red blood cell formation, and bolstering the immune system. By aiding in energy metabolism, it combats tiredness and fatigue, promoting overall vitality. These tablets are convenient and free from common allergens, making them suitable for vegans and vegetarians. 

With HealthAid's commitment to quality and purity, you can trust in the efficacy of this supplement to enhance your well-being. However, consulting a healthcare professional is advised, especially for individuals with underlying medical conditions or during pregnancy or nursing. Elevate your health with HealthAid Vitamin B12 1000mcg Tablets. 

Best with folate: Kirkman Laboratories TMG with Folinic Acid and Methyl B12

Product specifications 

Price & availability: £40.26 (buy Kirkman Laboratories TMG with Folinic Acid and Methyl B12 at Welzo)

Packing size: 120 capsules

Form: Capsules 

Dose of B12: 6 mcg

Vegan friendly: No (only vegetarian)

Serving size: 1-2 capsules per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 160 reviews at Welzo)

Why do we choose it?: Kirkman's TMG with Folinic Acid and Methyl B12 stands out as a superior supplement, meticulously formulated to address unique health needs. It harnesses the power of potent TMG extracted from premium beet sources, delivering elevated doses that promote enhanced methylation and bolster immune function. A suggested daily intake of 1-2 capsules offers both convenience and assurance of safety. Kirkman's unwavering commitment to purity ensures it's hypoallergenic, making it suitable for individuals with various sensitivities. Kirkman's TMG with Folinic Acid and Methyl B12 is a top-tier choice for those seeking comprehensive support for their overall well-being.

Best sublingual formulation: Cytoplan Vitamin B12 Sublingual Tablets

Product specifications 

Price & availability: £11.15 (buy Cytoplan Vitamin B12 Sublingual Tablets at Welzo)

Packing size: 60 tablets

Form: Tablets

Dose of B12: 500 mcg

Vegan friendly: Yes

Serving size: 1 tablet per day (follow doctor’s recommendations)

User rating: 4/ 5 (based on 108 reviews at Welzo)

Why do we choose it?: Introducing Cytoplan's Vitamin B12 Sublingual supplement, the ultimate solution for combating vitamin B12 deficiency. Each bottle contains 60 high-potency tablets, providing 1mg of methylcobalamin and adenosylcobalamin, the active forms of vitamin B12, ensuring maximum absorption. Designed for vegans, vegetarians, and those with digestive conditions, it addresses various bodily functions, including energy metabolism, nervous system health, and immune function.

Rapid sublingual absorption allows for noticeable results. This supplement is free from artificial additives and is ideal for individuals with low B12 status or poor methylation. Elevate your wellness with Cytoplan's practical and convenient solution.

Best lozenges: Seeking Health Active B-12 5000 Lozenges 

Product specifications 

Price & availability: £33.01 (buy Seeking Health Active B-12 5000 Lozenges at Welzo)

Packing size: 60 lozenges

Form: Lozenges

Dose of B12: 5,000 mcg 

Vegan friendly: Yes

Serving size: 1 lozenge per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 122 reviews at Welzo)

Why do we choose it?: Seek Health's Active B12 / B-12 5000 Lozenges is a potent supplement that supports overall health and wellness. Each lozenge packs 5 mg (5,000 mcg) of two active coenzyme forms of vitamin B12, methylcobalamin and adenosylcobalamin. These easy-to-take lozenges dissolve quickly in the mouth, offering a delicious and convenient way to boost your B12 levels. Free from common allergens and artificial additives, they uphold Seeking Health'sHealth's commitment to quality and purity.

This high-potency formula may aid in methylation, support healthy homocysteine levels, and promote cognitive function and energy metabolism. Elevate your HealthHealth with Seeking Health's Active B12 / B-12 5000 Lozenges. 

Best for immunity: New Beginnings Methyl-Mate (Vitamin B12 as Methylcobalamin) 

Product specifications 

Price & availability: £35.84 (buy New Beginnings Methyl-Mate (Vitamin B12 as Methylcobalamin) at Welzo)

Packing size: 30ml

Form: Liquid

Dose of B12: 2,500 mcg per 0.5ml

Vegan friendly: No (only vegetarian)

Serving size: 0.5ml (follow doctor’s recommendations)

User rating: 4/ 5 (based on 132 reviews at Welzo)

Why do we choose it?: It introduces Methyl-Mate by New Beginnings, a potent supplement featuring Methylcobalamin, the active form of Vitamin B12, renowned for its high bioavailability. This 30ml bottle supports overall health, particularly the nervous system, brain function, and red blood cell production. Methyl-Mate's ultra-concentrated formula contains no flavourings or artificial preservatives. The recommended dosage is 0.5ml daily, held under the tongue for optimal absorption. 

Ideal for adults and children, it's a convenient and effective way to boost energy levels, support metabolism, and fortify heart health. Methyl-Mate is a testament to New Beginnings' dedication to purity and potency in their supplements. 

Best vegetarian formula: Biocare Vitamin B12 

Product specifications 

Price & availability: £14.28 (buy Biocare Vitamin B12 at Welzo)

Packing size: 30 capsules

Form: Vegi capsules 

Dose of B12: 500 mcg

Vegan friendly: No (only vegetarian)

Serving size: 1 capsules per day (follow doctor’s recommendations)

User rating: 5/ 5 (based on 70 reviews at Welzo)

Why do we choose it?: Experience the vitality-boosting power of Vitamin B12 with Biocare's 30 veg capsules. Packed with 500 mcg of hydroxocobalamin, this essential nutrient supports energy metabolism, nervous system function, and the reduction of fatigue. Ideal for vegetarians and vegans, it promotes overall well-being by aiding in red blood cell formation, immune system function, and psychological health. Biocare's unique formulation offers a non-methylated solution for those with sensitivities, ensuring optimal absorption and gentle support. With easy-to-swallow capsules and environmentally friendly packaging, Biocare delivers trusted quality backed by over 30 years of expertise. Elevate your health with Biocare's Vitamin B12 capsules and embrace vitality every day.

Frequently Asked Questions 

Which form of B12 is the best? 

According to research, cyanocobalamin is better absorbed and has a better retention rate. That's why it is the preferred choice. However, all forms are effective in correcting the deficiencies. 

What is the difference between Neurobion and Methycobal? 

Methycobal contains different forms of vitamin B12. It is used to correct B12 deficiencies. The Neurobion, on the other hand, includes a blend of B vitamins and is best for people with a deficiency of different B vitamins. 

What is the fastest way to correct B12 deficiencies? 

Besides supplements, various foods and natural products help correct B12 deficiencies. The best foods for this purpose are chicken, beef, liver, fish and seafood, e.g., clams, tuna fish, salmon and trout, fortified cereals, cheese, yoghurt, low-fat milk and eggs. 

Which fruits are rich in B12? 

Fruits and other plant-based sources are not rich sources of B12. Some fruits containing vitamin B12 are blueberries, bananas and apples. However, relying on something other than fruits is strongly advised. 

Which factors lower the B12 absorption in the body? 

While taking supplements for B12 deficiency, it is essential to consider factors that lower the absorption of B12 and, thus, the efficacy of supplementation. These factors include obesity, anaemia, inadequate intrinsic factor production, stomach conditions, intestinal disorders, surgical removal of the ileum, etc.

Bottom-line 

Vitamin B12 is a critical nutrient in energy metabolism, DNA synthesis, red blood cell synthesis, and healthy neurological functions. It is present in many animal products and fortified foods. However, some people, particularly older adults and people on vegan diets are at risk of developing deficiencies and need supplementation. 

While choosing the best product, it is necessary to keep in view the personal preferences and needs and select the products that are best suited and third-party tested for potency and purity. For better results, consult the healthcare provider and ask their opinion about the best products.

To go through the uses, deficiency signs, supplements and other information related to B12, visit the vitamin B12 webpage. To see the benefits of B12 injections, visit our webpage.