Doctor's Best Calm with Zembrin is a stress relief supplement that helps ease anxiety and sharpen focus thanks to Zembrin, a patented Sceletium tortuosum extract. This plant-based formula is built for daily use, delivering a calm, non-sedating mood lift that keeps your thinking clear on busy days. The brand has a long-standing commitment to science-based nutrition, tight quality control, and transparent sourcing that shoppers trust.

Available Sizes & Variants:

60 vcaps – convenient everyday dose for ongoing mood support.

Benefits & Features:

• Calms nerves and keeps mood balanced without making you drowsy.
• Zembrin helps mood and focus by gently modulating brain pathways that deal with stress.
• Non-drowsy formula makes it easy to take daily, even on busy days.
• Produced in GMP facilities with standardised Zembrin, ensuring quality and consistency across batches, and many shoppers also explore probiotics for gut health to support overall wellbeing.
• For best results, many users pair this with a regular routine and give it several weeks to support mood stability, attention and everyday calm with consistent use.

Doctor's Best Calm with Zembrin draws on science-based nutrition, using Zembrin, a branded Sceletium tortuosum extract sourced to high standards. Zembrin is produced under strict licensing in South Africa and carries GRAS status in the United States, with third party checks for authenticity. For those using calm magnesium or probiotics for gut health, this plant-based formula fits neatly into a balanced wellness plan. In practice, studies show reduced anxiety and improved mood and cognitive performance without sedation, helping you stay calm and focused. The brand's GMP manufacturing, transparent sourcing, and vegan-friendly formulation set it apart in the supplement space.

Zembrin (Sceletium tortuosum aerial parts extract), Zembrin (Sceletium tortuosum aerial parts extract)

• GTIN: 753950004566
• Manufacturer: Doctor's Best
• Categories: Best SellersDoctor's BestSubscribe & Save Products
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1 capsule daily with or without food, or as recommended by a nutritionally informed physician. Daily oral dose not to exceed 25 mg. Store in a cool, dry place. Consult your doctor before use if you are pregnant, nursing, or taking antidepressants or anxiety medications. Discontinue use two weeks prior to surgery. Keep out of reach of children.

Please consult the product packaging for accurate instructions on how to use the product.

*Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

The Active Ingredient Is: Sceletium tortuosum Extract (Zembrin)

Sceletium tortuosum extract, commonly known as Zembrin, is a well-known branded plant-based ingredient used to support mood balance and calm. This patented extract is derived from the above-ground parts of the plant and is a recognised herbal supplement ingredient.

This form is produced under South African licensing and is described as a standardised branded extract with safety assessments and GRAS status in the United States, which shows its authenticity and quality.

What Does Sceletium tortuosum Extract Do?

Scientific research suggests it helps modulate the serotonin system and may influence aspects of stress reactivity and mood, with findings indicating calmer mood and improved cognitive flexibility without sedation.

Dr. ter Huurne of the University of Groningen reported reductions in anxiety-related amygdala reactivity, supporting a role in mood and stress modulation as part of normal brain function.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Doctor's Best stands out to us for its science-led approach and well-established reputation in the global supplement field. The brand is renowned for transparency, rigorous ingredient selection, and a commitment to clinically researched, branded ingredients, which aligns with Welzo’s pursuit of trusted, evidence-based products. This heritage positions Doctor's Best as a dependable partner among competitors by emphasising quality and traceability from sourcing to formulation.

Calm with Zembrin benefits from the manufacturer’s capability to utilise standardized, branded ingredients and GMP-compliant production, underscoring a robust quality framework for this plant-based blend. The Zembrin® ingredient is produced under stringent licensing and traceability, with third-party validation of authenticity and safety, reinforcing confidence in product integrity. For Welzo customers, this translates into a product that is thoughtfully formulated to support focus and mood balance without sedative effects, backed by credible research.

Welzo selected Doctor's Best after our team of medical experts evaluated their brand reputation, testing practices, and manufacturing standards using our rigorous testing protocols. Our trust is reinforced by the brand’s clear commitment to quality and safety, which we reflect in our product curation. For more on our evaluation, visit our our team of medical experts and our rigorous testing protocols.