TMG with Folinic Acid and Methyl B12 is a methylation support supplement that helps keep heart health, mood balanced, and energy production. This brand, Kirkman Laboratories, is known for hypoallergenic formulas and rigorous Ultra Tested quality, making this a dependable choice for everyday wellbeing. Active ingredients include TMG, folinic acid and methylcobalamin (a methylcobalamin b12 supplement) to support methylation, heart health and energy metabolism.

Available Sizes & Variants:

200 capsules – convenient bottle for daily dosing.

Benefits & Features:

• Supports healthy methylation and homocysteine metabolism as a methylcobalamin b12 supplement.
• Includes folinic acid and methyl B12 to optimise methylation pathways for mood, energy and brain function.
• Designed for sensitive individuals, the hypoallergenic formula is gluten free and free from common allergens, giving you confidence that it supports daily wellbeing without irritants.
• May help reduce homocysteine levels, a factor tied to heart health, supported by methyl folate and b12 metabolism.
• Bioavailable forms aid absorption and steady daily levels.

Born from Kirkman Laboratories' long standing focus on hypoallergenic, rigorously tested supplements, this blend combines TMG, folinic acid and methylcobalamin in a reader friendly capsule. Ultra Tested quality means every batch is checked for purity, potency and contaminants, giving you confidence in what you take. The use of bioavailable forms helps your body use the methyl donors more efficiently, supporting mood, energy and brain function. It also supports methyl folate and b12 function for balanced homocysteine levels. If you’re after a liquid methylcobalamin vitamin b12 option, this capsule form isn’t it. It's a daily ally that many customers find reassuring for sensitive diets, and it works, quickly and easily and does not leave you greasy.

Trimethylglycine, di-calcium phosphate, calcium folinate, magnesium stearate (vegetable), methylcobalamin, plant cellulose capsule.

• GTIN: 812325021017
• Manufacturer: Kirkman Laboratories
• Categories: KirkmanNew ArrivalsPopular Supplement BrandsVitamin B12 (Cobalamin) Supplements & Tablets
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Consume 1-2 capsules per day or follow the recommended dosage. Take 4-8 vegetarian capsules daily or as directed by a qualified healthcare professional.

Please consult the product packaging for accurate instructions on how to use the product.

1. TMG with Folinic Acid and Methyl B12 provides essential nutrients for optimal methylation, a vital process for the body's detoxification and energy production.
2. This product contains Folinic Acid and Methyl B12, two forms of vitamin B that support healthy brain function and promote cardiovascular health.

The Core Ingredient Is: Trimethylglycine (TMG)

Trimethylglycine, also called TMG, is a natural methyl donor involved in methylation pathways essential for keeping your body functioning.

This version is included to back methylation processes and is paired with folinic acid and methylcobalamin to optimise use of methylation nutrients.

What Exactly Does Trimethylglycine Do?

TMG helps in passing methyl groups that take part in converting homocysteine to methionine, supporting normal metabolic function. This mechanism ties into healthy mood-related pathways and liver function, in line with EFSA and NHS backed nutrient roles.

Dr. Bottiglieri from Harvard University found that methylation nutrients are involved in the synthesis of SAMe and several neurotransmitters, contributing to cognitive health and mood regulation.

*This product is not intended to diagnose, treat, cure, or prevent any disease.

Kirkman Laboratories has built a solid reputation for hypoallergenic formulations and a rigorous Ultra Tested quality, reflecting a long-standing commitment to safety and transparency from a USA-based manufacturer. This heritage aligns with Welzo’s focus on rigorous, consumer-first standards and dependable sourcing. The brand’s focus on precise testing and allergen-conscious design helps us feel confident in choosing Kirkman as our supplier for this methylation-support supplement. Our medical team our medical team evaluated Kirkman’s approach to quality, including its emphasis on third-party testing and compliance with cGMP, reinforcing our confidence in their manufacturing culture and oversight the standards we enforce.

This product is especially well matched for a methylation-focused formula, pairing TMG with Folinic Acid and Methyl B12 in a hypoallergenic, gluten-free profile. Kirkman’s established reputation for quality control and its Ultra Tested framework make them stand out against competitors when we weigh reliability, safety, and steady access to clinically relevant, well‑formulated ingredients.