E45 Skin Care Products

E45 is a leading dermatological skincare brand trusted for its gentle, clinically proven formulas that soothe dry skin, repair the skin barrier and support long-term hydration. Customers looking to buy E45 online often seek solutions for eczema, dermatitis, psoriasis and sensitive skin. The Welzo E45 collection includes creams, lotions, washes and emollients designed for children and adults with dry or irritation-prone skin.

What is E45?

E45 is a dermatology-led British skincare brand established in 1952. It was originally created for hospital dermatology wards and quickly became widely used for its non-greasy, clinically tested emollient formulations. E45 products are designed to treat dry skin conditions by forming a protective layer that prevents moisture loss while soothing irritation. Today, E45 remains a first-line choice for eczema management, dry skin flare-ups and daily skincare routines that require gentle, fragrance-light support.

Benefits and Features of the Welzo E45 Collection

  • Clinically proven emollients: Hydrate deeply and lock in moisture.
  • Suitable for eczema, psoriasis and dermatitis: Non-irritating formulas developed for sensitive skin.
  • Suitable for all ages: Including babies and older adults with delicate skin.
  • Non-greasy and fast-absorbing: Ideal for daily use and layering with medical treatments.
  • Backed by decades of dermatological use: A trusted brand in UK healthcare settings.

Why is E45 Important?

Dry skin and barrier dysfunction can worsen conditions like eczema, dermatitis and psoriasis. E45 provides consistent hydration and skin-barrier repair, helping improve comfort, reduce itching and restore the skin’s protective function. Many patients combine E45 with products from our baby & child skin conditions range or targeted treatments within eczema care to manage chronic symptoms more effectively.

How to Use E45 Products

Application methods vary depending on the product:

  • E45 Cream: Apply generously to dry areas 2–3 times daily.
  • E45 Itch Relief Cream: Use on itchy, irritated skin to calm flare-ups.
  • E45 Lotion: Suitable for whole-body daily moisturising.
  • E45 Wash or Shower Cream: A soap-free cleanser ideal for sensitive or eczema-prone skin.

E45 can be layered with medical treatments and is often paired with related essentials like antiseptics or first aid products for irritated or broken skin.

Types of E45 Available on Welzo

  • E45 Cream: Iconic moisturiser for dry, flaky or eczema-prone skin.
  • E45 Itch Relief Cream: Contains lauromacrogols and urea to soothe itching.
  • E45 Lotion: Lightweight, fast-absorbing moisturising lotion.
  • E45 Wash Cream: Soap-free alternative for gentle cleansing.
  • E45 Emollient Bath Oil: Hydrating bath additive for dry skin therapy.

Most Popular E45 Products

  • E45 Dermatological Cream
  • E45 Itch Relief Cream
  • E45 Moisturising Lotion
  • E45 Wash Cream
  • E45 Emollient Bath Oil

Customers often buy E45 alongside other soothing categories such as moisturisers or body skincare for complete hydration routines.

Statistics, Research, Expert Information and Quotes

Clinical studies show that emollients like E45 can improve skin hydration by up to 60% after consistent use and can reduce flare-up frequency in eczema-prone individuals. E45 formulations help rebuild the lipid barrier, which is essential for preventing water loss and irritation.

“E45 is widely used in dermatology because of its consistency, simplicity and effectiveness for dry and irritated skin. It is suitable for everyday use and for managing conditions such as eczema and dermatitis.”
— Dr Sameer Nakedar, MBBS, Clinical Lead at Welzo

How We Select the E45 Range on Welzo

  • All products undergo clinical review by our in-house medical team.
  • We prioritise formulas with proven dermatological benefits.
  • Products must demonstrate safety, suitability and clear usage instructions.
  • We ensure compatibility with related categories such as skin care and irritated eye care for multi-symptom conditions.

Trusted by Experts and Welzo Quality Assurance

E45 Reviews

Read real customer experiences with E45 products:

Welzo Reviews

FAQs

1. Is E45 suitable for eczema?
Yes. E45 is frequently recommended for eczema due to its barrier-repairing emollients.

2. Can babies use E45?
Yes, many E45 products are suitable for infants and children. For targeted issues, see our baby & child health category.

3. Is E45 fragrance-free?
Most E45 products are formulated with little to no fragrance and are suitable for sensitive skin.

4. Can E45 be used on broken skin?
Mildly broken skin is often suitable, but deeper wounds should be treated with products from the plasters or bandages categories.

5. How often should I apply E45?
Apply 2–4 times daily or as needed to keep skin moisturised.

6. Does E45 help with psoriasis?
It can soothe dryness and scaling, although severe psoriasis may need additional treatment.

7. Can E45 cause irritation?
It is unlikely but possible; discontinue use if irritation occurs.

8. Is E45 greasy?
No — its non-greasy formula makes it ideal for daily use.

9. Is E45 a steroid cream?
No. It is an emollient moisturiser.

10. Do I need a prescription for E45?
No, all E45 products are available to purchase online without a prescription.

11 products

Frequently Asked Questions