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Progesterone Supplements

Explore our range of progesterone supplements designed to support healthy hormone balance, menstrual comfort and perimenopausal and menopausal wellbeing. Whether you’re looking for oral progesterone capsules, topical progesterone creams or combination hormone-balancing formulas, you can compare options, check ingredients and buy progesterone supplements online with Welzo in just a few clicks. For broader hormonal support, many customers also browse our Hormone Imbalance Support and Women’s Health Supplements collections.

What Are Progesterone Supplements?

Progesterone supplements are products that provide either bioidentical progesterone or progesterone-like compounds (progestogens) to help support and stabilise hormone levels. They are often used alongside lifestyle changes and medical care to ease symptoms linked to low or fluctuating progesterone, such as irregular periods, mood changes, sleep disturbance or perimenopausal discomfort.

Some progesterone supplements are formulated as stand-alone progesterone, while others combine progesterone with nutrients such as magnesium, vitamin B6 or omega-3 fatty acids to support overall hormone metabolism. Certain products may be used within broader menopause or fertility programmes available through your healthcare provider.

Benefits and Features of the Welzo Progesterone Supplements Collection

The Welzo Progesterone Supplements Collection has been curated to provide options that help support natural hormone balance at different life stages. Key features include:

  • Hormone balance support: Formulas designed to complement the body’s own progesterone production and help counter symptoms of relative oestrogen dominance.
  • Female health focus: Products that support menstrual regularity, perimenopause and menopause comfort, mood stability and sleep quality.
  • Evidence-informed ingredients: Many products feature nutrients commonly used for women’s hormone health, such as vitamin B6, magnesium and omega-3s.
  • Flexible formats: Choose from capsules, tablets, drops or topical creams depending on your preferences and your clinician’s advice.
  • Independent testing: Selected products are batch-tested for purity and potency, with clear labelling so you know exactly what you’re taking.

If you’re looking to support wider hormonal wellbeing alongside progesterone, you may also find our Menopause Support Supplements and Fertility Supplements helpful.

Why Is Progesterone Balance Important?

Progesterone plays a central role in the menstrual cycle, early pregnancy and overall hormone balance. It helps stabilise the uterine lining, counterbalances the effects of oestrogen and supports mood, sleep and nervous system calm. When progesterone is low relative to oestrogen, some people may notice symptoms such as breast tenderness, irritability, heavy or irregular periods and difficulty sleeping.

During perimenopause and menopause, progesterone levels can fluctuate significantly. This hormonal shift is one reason many women explore progesterone-containing products as part of a wider menopause plan that may also include lifestyle changes and, where appropriate, hormone replacement therapy (HRT) prescribed by a clinician.

If you’re concerned about your hormone levels, consider exploring our Women’s Health Tests range, which includes hormone blood tests that can be organised from home and reviewed with a healthcare professional.

How to Use Progesterone Supplements Safely

Always follow the directions on the product label and any personalised advice from your doctor, pharmacist or specialist. Depending on the format, progesterone supplements may be taken orally, applied to the skin or used as part of a structured protocol.

  • Follow the recommended schedule: Some products are taken daily, while others are used during specific phases of the menstrual cycle or as part of a menopause or fertility plan.
  • Take with food if advised: Many oral supplements are best taken with a meal or snack to support absorption and minimise digestive discomfort.
  • Topical use: If using a cream, apply only to the areas suggested on the label and avoid broken or irritated skin.
  • Monitor your symptoms: Track changes in mood, sleep, cycle regularity and other symptoms so you can discuss progress with your clinician.

Progesterone supplements are not suitable for everyone. Always speak to a healthcare professional before starting any hormonal product, especially if you are pregnant, breastfeeding, have a history of hormone-sensitive conditions or are taking prescribed HRT or contraceptive medication.

What Are the Different Types of Progesterone Supplements Available?

On Welzo, you’ll find several progesterone-related options to suit different needs and preferences, including:

  • Oral progesterone capsules and tablets – commonly used in hormone-balancing protocols under medical supervision.
  • Topical progesterone creams – applied to the skin in measured amounts, often used in perimenopause or menopause support plans.
  • Combination hormone formulas – products that blend progesterone with nutrients such as magnesium or B vitamins to support overall hormonal and nervous system balance.
  • Supportive nutrients: non-hormonal supplements that may support progesterone pathways and female health, such as targeted menopause support or pregnancy vitamins, used alongside professional guidance.

What Are the Most Popular Progesterone Supplements Available?

Customer favourites within our progesterone collection frequently include:

  • Cycle support formulas combining progesterone with key nutrients to help ease PMS-like symptoms and support regular cycles.
  • Perimenopause and menopause blends that include progesterone and other ingredients chosen to help ease hot flushes, night sweats and sleep disturbance.
  • Fertility-focused products used within medically supervised programmes to support luteal phase stability and early pregnancy care.

Alongside progesterone, many customers also choose omega-3 and general women’s health supplements to support heart, brain and immune function as part of a complete wellbeing routine.

Statistics, Research and Expert Insights on Progesterone

Clinical research highlights progesterone’s central role in reproductive health, sleep regulation and mood. Progesterone helps prepare and maintain the uterine lining for potential pregnancy, moderates the stimulating effects of oestrogen and interacts with receptors in the brain linked to relaxation and sleep quality. Shifts in progesterone across the menstrual cycle, pregnancy and menopause are therefore closely tied to how many women feel day to day.

Experts generally recommend that any progesterone therapy or supplementation is tailored to the individual, with consideration of age, symptoms, medical history and blood test results where appropriate. This is why it’s important to work closely with a qualified clinician when using progesterone-containing products.

If you’d like to understand more about this hormone before choosing supplements, you can read our in-depth guide “What is progesterone?” for a detailed overview of how progesterone works and how levels change throughout life.

How We Select Our Progesterone Supplements Collection on Welzo

Our clinical and product teams carefully review each progesterone supplement before it is listed on Welzo. Selection criteria include:

  • Formulation transparency: Clear labelling, with full disclosure of progesterone content, supportive nutrients and excipients.
  • Evidence-informed ingredients: Preference for formulations aligned with current scientific understanding of hormone balance and women’s health.
  • Manufacturing standards: Products manufactured in facilities that follow robust quality systems and safety checks.
  • Independent verification: Use of third-party testing where available to confirm identity, purity and potency.
  • Real-world feedback: Ongoing review of customer reviews and practitioner feedback to ensure products meet expectations in practice.

Many customers combine progesterone supplements with lifestyle changes and targeted supports from our broader menopause support and hormone imbalance ranges for a more holistic approach.

Trusted by Experts and Verified Progesterone Supplement Quality on Welzo

At Welzo, our goal is to make specialist hormone support accessible while maintaining high clinical and quality standards. Our medical and nutrition experts review brands for ingredient sourcing, dose appropriateness and label accuracy, and many products are used and recommended within practitioner-led care.

You can learn more about the clinicians and pharmacists who help shape our supplement ranges on the Welzo Staff page. For added reassurance, we also publish our Ingredient Quality & Purity Certifications and Supplement Quality Standards & Certifications, which set out how we assess safety, purity and manufacturing quality across all supplements we stock.

Progesterone Supplement Reviews

Many customers report improvements in sleep, mood steadiness, cycle regularity and perimenopausal symptoms when progesterone supplements are used as part of a wider care plan overseen by a healthcare professional. Others value the clear labelling, high-quality ingredients and the ability to browse multiple options in one place.

To see what real users think of their hormone and supplement purchases, visit Welzo Reviews for up-to-date customer feedback and ratings across our full range of products.

Frequently Asked Questions About Progesterone Supplements

Who might consider taking progesterone supplements?

Progesterone supplements may be considered by women experiencing symptoms of low or fluctuating progesterone, such as irregular periods, problematic premenstrual symptoms or perimenopausal complaints. They are sometimes used within fertility or menopause care plans. However, any progesterone-containing product should only be started after discussion with a doctor or specialist who can assess your individual situation.

Are progesterone supplements the same as HRT?

Some progesterone supplements form part of hormone replacement therapy, while others are dietary supplements designed to support general wellbeing. Prescription HRT is a regulated medical treatment that usually combines oestrogen with progesterone or a similar progestogen. Over-the-counter progesterone products are not a substitute for personalised medical care, and you should never alter prescribed treatment without consulting your clinician.

Can I take progesterone supplements alongside the contraceptive pill?

Because most contraceptive pills already contain synthetic progesterone or progestogens, adding extra progesterone on top could interfere with their action or increase side-effects. It’s important to speak to your GP, gynaecologist or prescribing clinic before combining any progesterone supplement with hormonal contraception.

How long does it take to notice a difference with progesterone supplements?

This varies from person to person. Some people notice changes in sleep, mood or cycle comfort within a few weeks, while for others it may take several cycles of consistent use. Your clinician can help you decide on an appropriate review period and whether adjustments are needed based on your symptoms and any test results.

Are progesterone supplements safe to use during pregnancy?

Progesterone is a key pregnancy hormone, but taking additional progesterone during pregnancy should only be done under direct medical supervision. In some situations, a specialist may prescribe progesterone as part of fertility or early pregnancy care. Do not start or continue any progesterone supplement in pregnancy without explicit advice from your doctor or midwife.

Do progesterone supplements cause weight gain?

Some people report changes in appetite, fluid retention or body weight when using hormone-related products, but responses are highly individual and influenced by diet, activity levels, sleep and other medications. If you notice unwanted changes in weight or bloating after starting a progesterone supplement, discuss this with your clinician so they can review the dose, formulation and your wider health.

What side-effects should I look out for?

Possible side-effects of progesterone-containing products can include breast tenderness, spotting, headaches, mood changes or drowsiness. Serious side-effects are uncommon but require urgent medical attention. Always read the product information leaflet carefully and contact your doctor promptly if you experience anything unusual or worrying.

Should I have a blood test before using progesterone supplements?

While not always essential, hormone blood tests can provide useful information about your baseline progesterone, oestrogen and other hormone levels. This can help your clinician to decide whether progesterone-containing products are appropriate, what dose might be suitable and how to monitor your response over time. Talk to your doctor about whether testing is recommended in your case.

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