Antivert - Uses, Side Effects and Information

Meclizine's pharmacokinetics have not been studied in human studies.

However, a rat study revealed that meclizine is rapidly and almost completely absorbed from the digestive system, reaching peak plasma concentrations 1-2 hours after oral administration. Meclizine is widely disposed throughout the body, with the brain having the highest concentrations. Meclizine has a 12-hour elimination half-life. Meclizine is primarily excreted through hepatic metabolism, with only a small percentage (10%) ending up in the urine unchanged.

Meclizine's pharmacokinetics are not fully understood. According to theory, the drug's metabolites are excreted in the urine after being metabolized in the liver. Meclizine has a half-life of two to three hours.