P-5-P with Magnesium Bisglycinate (Hypoallergenic) helps support neurological and metabolic health, delivering steadier moods, smoother nerves, and better muscle function for daily life. The star ingredient is P-5-P, the active form of vitamin B6, paired with easy-to-absorb magnesium bisglycinate to back up nerves and muscles. Kirkman Laboratories has a long history of hypoallergenic production and rigorous purity testing, including their Ultra Tested process.

Available Sizes & Variants:

100 capsules – standard bottle size for daily use.

Benefits & Features:

• Supports nerve health with steady nutrient delivery.
• Star ingredients P-5-P and magnesium bisglycinate work together to support cognitive function and calm nerve signals, helping daily tasks feel more manageable overall.
• Ideal for daily use, especially for sensitive individuals seeking hypoallergenic formulas.
• Designed with Kirkman Ultra Tested quality standards, it's produced in U.S. facilities to help ensure purity and reduce the chance of allergens.
• Proactive support for muscle tone and relaxation makes this a practical choice for busy days, workouts, and evenings when you want feel good calm without compromise.

From its pedigree, Kirkman Laboratories has stood for purity since 1949, with cGMP certified facilities and the Ultra Tested process, which goes beyond typical standards to verify contaminants. P-5-P and magnesium bisglycinate are combined to support neurological, metabolic, and muscular health, aligning with Kirkman's commitment to hypoallergenic, trusted supplements. Magnesium glycinate is the star magnesium form for easy absorption. Some wellness routines pair this with a vitamin d supplement and probiotics to round out daily nutrition.

Vegetarian Capsule (hypromellose and water)

• GTIN: 733739000000
• Manufacturer: Kirkman Laboratories
• Categories: Blood Pressure SupplementsHypoallergenic Makeup ProductsKirkmanMagnesium SupplementsMineralsNew ArrivalsPeriod PainPopular Supplement BrandsStress Relief & Calming Supplements
• Best buy: 6 - 24 months+

United Kingdom & Rest of the World Shipping Details:
Same day dispatch for orders placed by 2pm (Orders after 2pm dispatched next working day).

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

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Take one capsule daily or as instructed. You can open the capsules and mix the contents with food or drinks. As a dietary supplement\, take one softgel per day with a meal\, or as directed by your health care practitioner.

Please consult the product packaging for accurate instructions on how to use the product.

The Active Ingredient Is: Vitamin B6 (Pyridoxal-5'-Phosphate)

Vitamin B6 in its active form, pyridoxal-5'-phosphate, is a water-soluble vitamin essential for normal metabolic and neurological function.

This form is an active metabolite of vitamin B6 and is presented in a hypoallergenic formulation to support tolerance and purity.

What Does Vitamin B6 Do?

Vitamin B6 is involved in amino acid metabolism and neurotransmitter synthesis, and it participates in homocysteine metabolism, contributing to normal brain and nerve function.

Evidence suggests roles in metabolic and neurological contexts and supports normal mood and cognitive function in line with EFSA and NHS documentation. In this product, the combination with magnesium bisglycinate aligns with research on nutrient synergy for general physiological support.

Dr. Chiang of the University of California found that active B6 forms participate in neurotransmitter synthesis and amino acid metabolism, supporting the described functions.

Magnesium bisglycinate is the accompanying mineral in this formulation and is noted for high bioavailability and roles in muscle and nerve health; together, these ingredients support normal muscular and neurological function.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Kirkman Laboratories stands out for its commitment to purity and safety from the very first step of production. This brand, with a long history of cGMP-compliant manufacturing and a reputation for scientific rigour, remains a trusted choice for those with sensitivities and special dietary needs. The Ultra Tested® protocol exemplifies Kirkman’s dedication to transparency and contaminant screening, with in-house verification of raw materials and finished products, and U.S.-based production that emphasises strict quality controls. This is why we favour Kirkman over other suppliers in this space.

Their heritage since 1949 and consistent recognition for quality assurance position Kirkman as a credible partner for hypoallergenic formulations. The brand’s emphasis on precise ingredient purity and allergen-conscious manufacturing aligns perfectly with P-5-P with Magnesium Bisglycinate (Hypoallergenic), ensuring a clean, well-tolerated supplement background. This brand-versus-alternatives distinction is driven by their proven safety standards and ongoing commitment to transparency, supported by our team’s evaluation and our medical team as well as our quality assurance criteria.

In summary, Kirkman provides a product match that is both robust in quality and well-suited to the needs of this specific supplement, justifying our selection decision.