5-HTP (5-Hydroxytryptophan) supports mood, sleep, and appetite control by boosting serotonin, with vitamin B6 aiding its conversion, all produced by Thorne under GMP standards. Active ingredients include 5-HTP and B6, with Griffonia simplicifolia seed extract used as the natural source. Thorne manufactures in the USA with GMP controls and rigorous lot testing to help ensure quality you can trust. This combination delivers a trusted, high quality supplement backed by a heritage of rigorous manufacturing.

Available Sizes & Variants:

90 capsules 5-HTP – convenient daily capsules for mood, sleep and appetite support.

Benefits & Features:

• Mood support is enhanced as serotonin production increases.
• Supports daily balance by promoting steady energy and calmer cravings.
• Optimised serotonin synthesis comes from the synergy of 5-HTP and vitamin B6, supporting mood stability, better sleep, and steadier appetite control.
• Griffonia simplicifolia seed extract provides the natural source for 5-HTP.
• Quality is paramount, with Thorne manufacturing in the USA under GMP and performing strict lot testing for contaminants to ensure Peak X free product you can trust.

Thorne has built a reputation for purity and reliability, with 5-HTP sourced from Griffonia simplicifolia and manufactured in the USA under strict GMP controls. The brand emphasises contaminant screening, keeping Peak X free products you can trust, while vitamin B6 supports efficient serotonin synthesis. This blend is relevant for memory supplements, brain health supplements and the best brain function supplement category.

Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.

• GTIN: 693749503026
• Manufacturer: Thorne
• Categories: 5-HTP SupplementsNew ArrivalsPopular Supplement BrandsSleep & Relaxation SupplementsSupplements for AnxietyThorne SupplementsTryptophan
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1-2 capsules three times a day, or as directed by your healthcare provider. Take 1 capsule one to three times daily or as recommended by your healthcare practitioner.

Please consult the product packaging for accurate instructions on how to use the product.

The Active Ingredient Is: 5-Hydroxytryptophan (5-HTP)

5-Hydroxytryptophan is a compound that gets converted in the brain to serotonin, a neurotransmitter linked with mood, sleep and appetite regulation.

This form is drawn from Griffonia simplicifolia seeds, and the product includes Vitamin B6 as Pyridoxal 5'-phosphate to support the serotonin synthesis pathway.

What Does 5-Hydroxytryptophan Do?

5-HTP helps support normal serotonin production, with Vitamin B6 aiding its conversion to serotonin in the brain. Dr. Shaw of the University found that 5-HTP is converted in the brain to serotonin, a neurotransmitter involved in mood, sleep and appetite.

Studies suggest 5-HTP may support mood, sleep quality and appetite regulation in line with EFSA-informed understanding of serotonin pathways.

This supplement isn't meant to diagnose, treat, cure, or prevent any disease.

Welzo chose Thorne as our partner for 5-HTP because this brand leads with manufacturing excellence and a long-standing commitment to quality. Welzo sources Thorne products made in the USA using a carefully balanced mix of domestic and imported ingredients, underpinning a strong domestic supply chain and consistent production standards. The manufacturer adheres to Good Manufacturing Practices (GMP) and conducts really thorough lot testing to ensure contaminant safety, including screening for Peak X as a purity marker. This combination of site integrity and explicit quality controls explains why Thorne is trusted by professionals in the field. For our verification, this brand’s approach aligns with our standards, and the team at Welzo reviews their practices through our medical team for compliant, safe supplementation, reinforced by our quality checks on ingredient sourcing and purity.

Thorne is well recognised for its commitment to purity and safety, with U.S. manufacturing and GMP-compliant operations. The product is designed with thoughtful formulation—5-HTP from Griffonia simplicifolia and vitamin B6 as Pyridoxal 5'-Phosphate to support the intended pathway, without artificial preservatives or major allergens. This brand stood out in our evaluation for its transparent quality controls and dedicated manufacturing philosophy. This is why Welzo endorses Thorne for this specific 5-HTP product. This brand evaluation was conducted by our medical team and aligned with how we verify ingredient quality.