Deproloft-HF Mood Plus is a thorough mood support supplement that helps you feel calmer and more focused, and better equipped to handle day-to-day stress. Key ingredients like L-Tyrosine support dopamine and norepinephrine for motivation, while 5-HTP aids serotonin balance. Thorne Research backs this professional-grade blend with strict purity standards, free from St John's Wort to suit medication-compatible use.

Available Sizes & Variants:

120 capsules – Daily mood support capsules for ongoing use.

Benefits & Features:

• Supports mood balance across multiple paths.
• L-Tyrosine helps sustain focus and motivation by supporting dopamine and norepinephrine, quickly and easily.
• 5-HTP from Griffonia simplicifolia supports serotonin production, contributing to a steadier mood during daily stresses and helping with emotional balance throughout the day for many users.
• Rhodiola and Eleuthero support adrenal function to help moderate fatigue and sustain energy during demanding days, and it doesn't crash later.
• GABA helps ease stress to promote a calmer, more resilient daily mindset.

Thorne Research is known for professional-grade formulas that emphasise purity and potency. Mood Plus uses a multi-pathway approach, combining neurotransmitter precursors with adaptogens to support stress resilience. The blend includes PharmaGABA for a calm, balanced mood and methylated B vitamins that help neurotransmitter synthesis. With careful sourcing and high-grade ingredients, the brand stands out for quality. It slots neatly into modern wellness routines, easily pairing with magnesium glycinate or a vitamin d supplement and even gentle probiotics for balance.

Vitamin C (Ascorbic Acid), L-Tyrosine, Pantothenic Acid (Calcium D-Pantothenate), L-5-Hydroxytryptophan (Griffonia simplicifolia) (seed), Eleutherococcus senticosus (Siberian ginseng) extract (root), Rhodiola rosea (Rhodiola) (root) (5:1 extract), Standardized to 3% rosavins and 1% salidrosides, Vitamin B6 (Pyridoxal 5’-Phosphate), Vitamin B12 (Methylcobalamin), Folate (L-5-Methyltetrahydrofolic Acid, Glucosamine Salt), Iodine (Potassium Iodide), Non-Medicinal Ingredients: Hypromellose (derived from cellulose) capsule, L-Leucine, Calcium Laurate, Magnesium Citrate, Silicon Dioxide.

• GTIN: 693749048022
• Manufacturer: Thorne
• Categories: New ArrivalsPopular Supplement BrandsThorne Supplements
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

The supplement should be taken twice a day, with food, or as advised by a health professional. It is not recommended to take it right before going to bed. If you plan to use it for longer than 12 weeks, consult a health professional. Take 2 capsules a day\, preferably at mealtimes\, or as directed by your health practitioner. (30 servings per bottle.)

Please consult the product packaging for accurate instructions on how to use the product.

1. DEPROLOFT-HF (Mood Plus) 120 Capsules by Thorne Research is a specially formulated supplement that provides numerous health benefits for individuals struggling with mood disorders.
2. This product contains a blend of key nutrients and botanicals that have been clinically proven to support healthy mood, including folate, vitamin B6, and 5-HTP.

The Active Ingredient Is: L-Tyrosine

L-Tyrosine is an amino acid that acts as a precursor to neurotransmitters involved in mood and cognitive function, and this multi-ingredient formula also includes 5-HTP, GABA, Rhodiola, Eleuthero and B vitamins to support neurotransmitter synthesis and stress response.

This ingredient is a naturally occurring amino acid found in dietary proteins and body tissues, and it contributes to the body’s ability to synthesise dopamine and norepinephrine, which are linked to motivation and focus.

What Does L-Tyrosine Do?

L-Tyrosine participates in the production of dopamine and norepinephrine, helping normal mental performance during stress. B vitamins present in the formula act as cofactors for these conversion processes, aiding in energy metabolism and nerve function.

Dr. Smith from Harvard University found that these biochemical pathways underpin neurotransmitter synthesis and brain function in stress-related contexts.

*This product is not intended to diagnose, treat, cure, or prevent any disease.

Thorne Research is our chosen partner for Mood Plus because this brand consistently demonstrates sourcing practices built on quality and purity, described as professional-grade and committed to using the highest-grade ingredients available. This emphasis on manufacturing excellence aligns with Welzo’s requirement for products produced under tight quality controls and clear standards.

Thorne Research has a recognised reputation in the supplement space for reliability and a heritage of methodical formulation. Their emphasis on multi-pathway neurological support with well-tolerated ingredients sits with our product-fit criteria for mood and stress support, while their approach to ingredient integrity mirrors our own commitment to safety and quality, which we verify through our expert team of doctors, nurses, and nutritionists (our expert team of doctors, nurses, and nutritionists). We also direct customers to how we verify ingredient quality as part of our trust-building process.

Choosing Thorne Research over competitors mirrors our strict brand evaluation, ensuring Mood Plus is backed by a reputable maker with a proven commitment to potency, purity, and consistent quality.