SAMe from Jarrow Formulas provides the bioactive SAMe for supporting mood balance and joint comfort, and the enteric coating helps absorption and stability. Built by Jarrow Formulas, a brand known for science-led, quality-focused supplements. Expect clear daily energy for wellbeing and comfort with a trusted, vegan-friendly tablet. The formulation aligns a robust process, microbiological fermentation and an allergen-free, foil-packaged coating, with careful testing to help ensure you get dependable potency.

Available Sizes & Variants:

400 mg SAMe tablet – standard dose for daily support.

Benefits & Features:

• Supports mood balance for daily calm.
• The enteric coated tablet is engineered to resist stomach acid and improve absorption, so the active SAMe reaches the gut where it's most effective, helping you notice clearer mood and joint benefits.
• Suitable for vegetarians and free from common allergens, making it easy to fit into many diets.
• Quality is supported by careful fermentation processes and packaging to protect potency.
• Designed for daily use as part of a balanced wellbeing routine, helping to support overall vitality.

Built on Jarrow Formulas’ commitment to scientific rigour and stability, this SAMe supplement uses microbiological fermentation and an allergen-free production process. The enteric coated tablet resists stomach acid, helping the active SAMe perform in the gut. Fans of the brand value its pharmaceutical grade, tested potency, and transparent manufacturing standards. For a holistic wellbeing routine, some customers pair SAMe with other lines, including supplement vitamin D or collagen dietary supplement.

S-Adenosyl Methionine (from 800 mg of SAMe Tosylate Disulfate)

• GTIN: 790011200420
• Manufacturer: Jarrow Formulas
• Size: 60 Tablets
• Categories: Jarrow Formulas
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take 1 tablet of Jarrow Formulas SAMe 400 daily on an empty stomach, or as directed by your qualified healthcare professional. Store in a cool, dry place. Keep out of reach of children. Consult a doctor before use if you are taking prescribed medications such as antidepressants, have Parkinson's disease, bipolar disorder, or are pregnant or breastfeeding. Do not exceed the recommended dose. Discontinue use and consult a doctor if any unwanted reactions occur.

Please consult the product packaging for accurate instructions on how to use the product.

*Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

The Active Ingredient Is: S-Adenosyl Methionine (SAMe)

S-Adenosyl Methionine, commonly abbreviated as SAMe, is a natural compound involved in critical methylation reactions and neurotransmitter production. This formulation uses a stabilized SAMe derived from SAMe tosylate disulfate and is designed for enteric-coated delivery. (This is the version many customers appreciate for gut-friendly absorption.)

This form is produced through microbiological fermentation and is designed to optimise stability and absorption in the gut.

What Does S-Adenosyl Methionine (SAMe) Do?

SAMe helps with normal methylation processes that support neurotransmitter balance and might assist liver detox pathways. It also ties into joint health by backing cartilage function and overall mobility as seen in clinical contexts. (What’s interesting is how this links mood and liver support together.)

In people, SAMe links to mood balance and liver support via its role in antioxidant production and metabolic processes that go on inside the body.

This supplement isn't meant to diagnose, treat, cure, or prevent any disease.

Why Jarrow Formulas SAMe is Welzo Selected. Jarrow Formulas brings production reliability with a science-led approach that lines up with our commitment to dependable quality, and it mirrors the way we expect consistency in every batch. The brand is known for its stable, pharmaceutical-grade formulations and its focus on rigorous manufacturing controls that safeguard product integrity during low temperature and humidity storage, which is important for long lasting effectiveness. This heritage of reliability has made Jarrow Formulas a trusted partner in the supplement space, recognised by professionals for robust, research-informed offerings, and it’s a part of why we feel confident recommending them. This brand was evaluated by our team of medical experts for compliance with our ingredient quality and purity standards.

Product-specific fit and quality are clear strengths. The enteric-coated, fermentation-based process supports stability and bioavailability, and the formulation is vegetarian-friendly and free from common allergens. Such specifications mirror our standards for safety and consistency, making Jarrow Formulas SAMe a natural fit for this supplement category and a dependable partner for Welzo customers seeking clarity and reliability in their daily regimen. This brand stands out through its persistent commitment to quality, scientific backing, and transparent manufacturing practices.