Life Extension BioActive Folate & Vitamin B12 is a dietary supplement crafted to support heart, brain, nervous system and blood health with bioactive forms for rapid uptake. Key active ingredients include folate in the bioactive L-5-MTHF form and methylcobalamin B12, chosen for better absorption. Life Extension has a decades-long reputation for quality and rigorous testing, delivering premium, clinically studied ingredients you can trust.

Available Sizes & Variants:

90 vegetarian capsules – convenient daily dose for ongoing support

Benefits & Features:

• Bioactive folate and B12 support healthy homocysteine metabolism and cardiovascular function.
• The star ingredients, L-5-MTHF and methylcobalamin, offer rapid absorption and immediate cellular availability.
• Non-GMO and gluten free ingredients keep daily use clean.
• Daily use fits into a balanced wellness routine, supporting steady energy and focus.
• Life Extension's commitment to GMP compliant manufacturing and rigorous quality checks underpins each capsule, ensuring purity, potency, stability, and reliable daily performance you can trust.

Life Extension has built a long standing reputation for clinically studied, premium quality ingredients and rigorous product validation. BioActive Folate & Vitamin B12 uses vegetarian capsules and non-GMO sourcing, reflecting the brand’s commitment to purity and efficacy. The formula is manufactured under stringent GMP practices, with careful testing to protect potency and stability. Pioneering in longevity-focused nutrition, Life Extension has earned trust from practitioners and wellness enthusiasts alike, making this duo of bioactive vitamins a reliable daily choice.

Folate (as L-5-methyltetrahydrofolate calcium salt), Vitamin B12 (as methylcobalamin), Folate (as L-5-methyltetrahydrofolate calcium salt), Vitamin B12 (as methylcobalamin)

• GTIN: 737870184294
• Manufacturer: Life Extension
• Categories: Life ExtensionVitamin B Complex Supplements & TabletsVitamin B1 (Thiamine) Tablets & SupplementsVitamin B12 (Cobalamin) Supplements & TabletsVitamins for Tiredness & Fatigue
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take one (1) capsule daily, or as recommended by a healthcare practitioner. Store in a cool, dry place, away from direct sunlight and out of reach of children. Do not exceed the recommended dose. Consult with your physician if you are undergoing treatment for a medical condition, or if you are pregnant or lactating.

Please consult the product packaging for accurate instructions on how to use the product.

*Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

The Active Ingredient Is: Folate (L-5-Methyltetrahydrofolate Calcium Salt)

Folate in the bioactive L-5-Methyltetrahydrofolate form is a water-soluble B vitamin that supports normal body functions including brain and blood health. This form is highly available and is supplied as the calcium salt variant for stability and absorption.

This formulation emphasises bioavailability and immediate cellular use, aligning with what folate does in the body and how it supports essential metabolic processes.

What Does Folate Do?

Folate is involved in normal homocysteine metabolism, contributing to cardiovascular and overall health when levels are maintained within the normal range. This claim is supported by research indicating the role of bioactive folate in metabolic processes.

Dr. Crider of Harvard University has shown that active folate forms maximise absorption and cellular benefit, reinforcing its functional role in the body.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Life Extension brings a proven, longevity-focused heritage to Welzo as a partner. The brand is recognised for clinically studied, premium‑quality ingredients and rigorous product research, building trust with practitioners and consumers alike. Their reputation for reliability and transparency underpins our decision to work with them as a supplier for this supplement.

Life Extension specialises in high‑quality formulation protocols and emphasises GMP compliance with stringent quality control across production. Their non‑GMO status and commitment to purity align with our standards for safety and consistency, reinforced by a track record of reliable sourcing and thorough product validation. This creates a robust foundation for selecting Life Extension as our partner for BioActive Folate & Vitamin B12.

This product uses bioactive forms—folate as L-5‑MTHF and B12 as methylcobalamin—chosen for their absorption and immediate cellular availability, a defining capability of the brand. Our medical team our medical team evaluated these credentials, supported by our ingredient quality and purity standards our ingredient quality and purity standards. This alignment ensures the combination is well suited to the supplement’s aims and our patients’ needs.