Nutrex Lipo 6 Defining Gel targets stubborn fat zones with a topical delivery system to help shape and define your silhouette. It features actives like Theophylline, Yohimbine HCl, caffeine, resveratrol and capsaicin, along with supporting ingredients, all chosen for their role in topical fat management. Nutrex is a science-led brand that prides itself on quality standards and dedicated skincare solutions.

Available Sizes & Variants:

120 ml Defining Gel – handy tube perfect for targeted application on problem areas.

Benefits & Features:

• Target trouble zones with precise 2–4 pumps per session.
• Fast acting gel delivers a cooling, refreshing sensation each application.
• Star active ingredient Theophylline is the key active ingredient for localized fat reduction in topical applications, with Yohimbine HCl and capsaicin supporting delivery and warming sensations.
• Designed for daily use and smooth absorption, the gel supports a practical routine before workouts or daily activities.
• TopiSorb technology helps optimise skin delivery for more uniform coverage and faster feeling benefits.

Nutrex brings science-led skincare to life with Lipo 6 Defining Gel. The TopiSorb delivery system helps active ingredients reach the skin more efficiently, reflecting the brand’s dedication to practical, targeted solutions. The formula blends Theophylline with supporting actives to address localized fat in a convenient gel format, and it sits well alongside skin care products in a modern routine. It nods to Korean skincare ideas of light, fast absorbing textures that work with face moisturiser routines, making it a handy addition to daily regimens.

Water, Ethyl Alcohol, Benzyl Alcohol, Ethoxydiglycol, Menthol, Capsaicin, Arginine, Theophylline, Diacylglycerol, Resveratrol, Caffeine, Methyl Salicylate, Synephrine, Adipic Acid, Glycerin, Caprylic/Capric Triglyceride, Limonene, Carbomer, Triethanolamine.

• GTIN: 859400007689
• Manufacturer: Nutrex
• Categories: NutrexSports Supplements
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Apply 2-4 pumps of LIPO-6 DEFINING GEL to dry, clean skin by gently rubbing the gel into the desired fat area. Use 1-2 times per day, and on training days, apply 30 minutes prior to a workout for maximum effect. Best areas to apply include the stomach, lower back, love handles, glutes, and hamstrings. Store in a cool, dry place, out of reach of children. Consult a healthcare professional before use if you have skin sensitivities, are pregnant or nursing, or are under medical supervision. Discontinue use if skin irritation occurs.

Please consult the product packaging for accurate instructions on how to use the product.

Theophylline is an energising, stimulant-like compound applied topically to help targeted fat reduction through skin delivery mechanisms.

This form is used in topical creams to deliver the active ingredient locally and is cited in studies examining fat reduction with transdermal applications.

What Does Theophylline Do?

Theophylline applied to the skin has been linked with reductions in subcutaneous fat in controlled studies, contributing to local contour changes when paired with exercise [which varies by person].

Research points to a mechanism linked to topical fat processes and energy expenditure at the site of application.

Dr. Greenway from the University of Florida found that topical theophylline cream reduced subcutaneous fat after several weeks.

This effect is discussed in the context of local fat management and transdermal delivery as part of everyday fat handling in targeted areas.

This supplement isn't intended to diagnose, treat, cure, or prevent any disease.

Nutrex is our trusted partner for targeted topical fat-management solutions, delivering active ingredients through advanced transdermal delivery with TopiSorb technology. This focus on precise local delivery aligns with our commitment to science-led, results-oriented products, making Nutrex a natural fit for Welzo customers seeking focused sculpting support.

Nutrex has built credibility through a clear product framework that combines potent actives such as Theophylline, Yohimbine HCl, caffeine and capsaicin to support topical fat reduction discussions, while highlighting the strongest clinically substantiated ingredient in this context. Our medical team assesses formulations like this to ensure they meet Welzo’s standards for safety and efficacy, tying product design to real-world use. This brand is evaluated by our medical team for compliance with the standards we enforce.

Why Nutrex over competitors? Their commitment to a targeted delivery approach and a science-forward ingredient mix distinguishes them in our selection process. This brand is particularly suited for Lipo Defining Gel, where transdermal delivery and a curated actives profile aim to support defined results. Welzo’s selection framework combines brand reputation, product integrity and expert review to ensure you receive consistently reliable quality from a trusted partner.