Pyridoxal 5'-Phosphate is a dietary supplement that brings the bioactive form of vitamin B6 to help energy production, neurotransmitter synthesis, and overall nervous system health. This is backed by Thorne Research's strong quality standards, ensuring each capsule delivers a reliable, high quality source of B6 that supports energy, mood, and nervous system function.

Available Sizes & Variants:

180 veggie caps – Yeast free, gluten free capsules suitable for vegetarians.

Benefits & Features:

• Supports daily energy levels.
• Pyridoxal phosphate provides the enzyme ready form of vitamin B6 for immediate use in metabolism.
• As a dietary supplement, it supports neurotransmitter synthesis, helping mood and cognitive function, especially when dietary intake is limited.
• Works with magnesium for supporting women's health and PMS comfort.
• Thorne's GMP compliant manufacturing and third party verifications underpin the product's purity and potency, giving you confidence in every capsule and ensuring consistent quality across batches.

Pyridoxal phosphate is the coenzyme form of vitamin B6, the key active ingredient driving more than a hundred enzymatic reactions from neurotransmitter synthesis to homocysteine metabolism. In Thorne's P5P, the bioactive B6 is immediately usable, supporting energy flow, mood, and nervous system health. The product is yeast free, gluten free, and suitable for vegetarians, reflecting Thorne's commitment to purity. The brand's GMP standards and third party verifications help ensure consistent quality you can trust.

Vitamin B

• GTIN: 693749126034
• Manufacturer: Thorne
• Categories: B6 (P5P Form)New ArrivalsPopular Supplement BrandsThorne Supplements
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Take one capsule two to three times daily, or as advised by your healthcare professional. Mix one scoop daily in filtered water or beverage of choice\, or as directed by your healthcare professional.

Please consult the product packaging for accurate instructions on how to use the product.

The Active Ingredient Is: Vitamin B6 (Pyridoxal 5'-Phosphate)

Pyridoxal 5'-phosphate is the bioactive, tissue-ready form of vitamin B6 and functions as a coenzyme in numerous metabolic processes.

Pyridoxal 5'-phosphate is the bioactive, tissue-ready form of vitamin B6 and acts as a coenzyme in many metabolic processes.

What Does Vitamin B6 Do?

Scientific evidence suggests that vitamin B6 participates in neurotransmitter synthesis, amino acid metabolism, and homocysteine metabolism, which are relevant to normal energy production and nervous system function.

Scientific evidence suggests that vitamin B6 takes part in neurotransmitter synthesis, amino acid metabolism, and homocysteine metabolism, which are linked to normal energy production and nervous system function.

This information aligns with EFSA-style understanding that vitamin B6 supports these metabolic roles, contributing to normal energy production and cognitive function. Dr. Kennedy of University College London found that adequate B6 status is linked to mood regulation and cognitive performance.

This information aligns with EFSA-style understanding that vitamin B6 supports these metabolic roles, helping normal energy production and cognitive function. Dr. Kennedy of University College London found that adequate B6 status is linked to mood regulation and cognitive performance.

This supplement is not intended to diagnose, treat, cure, or prevent any disease.

This supplement is not intended to diagnose, treat, cure, or prevent any disease. This product is manufactured to high quality standards under GMP guidelines and is gluten-free, dairy-free, soy-free, and yeast-free for allergen safety.

This supplement is not intended to diagnose, treat, cure, or prevent any disease. This product is made to top quality standards under GMP guidelines and is gluten-free, dairy-free, soy-free, and yeast-free for allergen safety.

Thorne Research was chosen because the brand fits Welzo's strict supplier standards for quality, openness and scientific rigour.

Thorne is known for manufacturing excellence, following Good Manufacturing Practices (GMP) for pharmaceutical‑grade supplements and using advanced laboratory verification and batch purity validation protocols.

Their commitment to third‑party testing and independent audits reinforces trust in both ingredient authenticity and finished product safety, which we recognise as central to Welzo's quality standards. For a broader view of how we validate these standards, check our supplement quality standards and the expertise of Welzo's healthcare professionals in our evaluation process.

Thorne’s reputation for delivering the bioactive, clinically relevant P5P form of vitamin B6 fits really well with a product built for maximum bioavailability while guaranteeing allergen safety and vegetarian suitability. This brand stands out compared with competitors through rigorous cGMP manufacturing, thorough potency and purity testing, and clear transparency in sourcing and labeling.

Our team chose Thorne because the brand shows manufacturing excellence, third‑party validation and a compelling fit for the British market, supported by Welzo's expert vetting framework and the strong alignment with our product‑specific criteria.