Life Extension Optimized Folate helps support heart health and brain health by keeping homocysteine levels in check through the bioactive folate form, L-Methylfolate. L-Methylfolate is the usable bioactive folate your body can take straight away, skipping conversion hurdles. Life Extension backs every batch with a certificate of analysis and independent audits for quality you can rely on. That quality feels trustworthy. It’s built for daily use.

Available Sizes & Variants:

100 Vegetarian tablets - High potency L-Methylfolate in a convenient daily tablet.

Benefits & Features:

• L-Methylfolate helps lower homocysteine, supporting heart health.
• Star ingredient L-Methylfolate is the bioactive form of folate your body can use directly, making it considerably more effective for those with folate metabolism variations.
• Certified gluten free and non-GMO, the product ships with a certificate of analysis for every batch.
• For people with MTHFR variations, this folate form helps ensure the body receives folate efficiently.
• Life Extension's quality program includes NSF audits and batch certificates for trust.

Life Extension has built a reputation for rigorous quality and transparent sourcing. Every batch carries a certificate of analysis and undergoes independent NSF International audits. The active ingredient is L-Methylfolate, the bioactive folate the body can use directly, helpful for those with folate metabolism variations. The tablets are gluten free, non GMO, and suitable for vegetarians, reflecting the brand's commitment to allergen friendly, pure supplements.

Other Ingredients - microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.
Free From - Gluten

• GTIN: 737870193913
• Manufacturer: Life Extension
• Categories: CHECKOUT UPSELLLife ExtensionNew Arrivals
• Best buy: 6 - 24 months+

United Kingdom Shipping:

Orders placed by 2pm (Monday to Friday) are dispatched the same day. Orders placed after 2pm will be dispatched the next working day.

Free shipping on orders over £50 to the UK.

Returns: Our products are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 30 days in the same original and unopened packaging. Subject to T&C's.

Consume one tablet per day with food, or follow a healthcare professional's advice.

Please consult the product packaging for accurate instructions on how to use the product.

The Active Ingredient Is: L-Methylfolate (5-MTHF)

L-Methylfolate is the bioactive form of folate, a water-soluble B vitamin essential for normal body function. It is the biologically available form that the body can use directly in folate-dependent processes.

This form is the source of folate in this product, offering a readily usable form of vitamin B9 in vegetarian tablets.

What Does L-Methylfolate Do?

L-Methylfolate is involved in methylation processes that support healthy homocysteine regulation, a biomarker linked to cardiovascular and cognitive health. Dr. Marangoni of the University of Bari found that this form can influence homocysteine levels in research contexts.

EFSA-aligned understanding indicates its role in normal folate metabolism and neurological support through its bioactive action.

Dietary supplements are not a replacement for a balanced diet. Do not take more than the recommended amount. Keep in a cool, dry area away from light and heat. Ensure they are out of children's reach and view.

Folate -5-Methyltetrahydrofolate, Calcium Salt)as (6S: 1700 mcg

Life Extension brings deep formulation expertise and a proven track record in delivering high-purity dietary supplements, making it a standout partner for Life Extension Optimized Folate. The manufacturer is known for transparency and rigorous quality controls, including a certificate of analysis for every batch and independent audits by NSF International, reinforcing confidence in safe, consistent products. the certifications we require are met, with non GMO LE Certified and Gluten Free labels reflecting allergen and composition integrity.

Welzo selected Life Extension because of their heritage in advanced folate science, their clear manufacturing standards, and their commitment to accuracy and traceability. This brand’s emphasis on active L-Methylfolate (5-MTHF) within a well-regulated framework aligns with our supplier criteria and expert evaluation by our medical team.

For customers, this means a product designed to support healthy homocysteine management with a reliable quality system behind every tablet, giving confidence in daily use and consistency across batches.