Bumetanide may interact with any other drugs, supplements, or herbal products you may be taking. When a substance modifies how a drug functions, there is an interaction. This could be harmful or stop the medication from working properly.
Your doctor needs to carefully monitor all of your medications to help you avoid interactions. Tell your doctor about all of the drugs, supplements, and herbs you are taking. Speak with your doctor or pharmacist to learn how this medication may interact with other medications you are taking.
The following is a list of medications that may interact with bumetanide.
ACE inhibitors, including enalapril (Vasotec), captopril (Capoten), and lisinopril (Zestril).
NSAIDs such as celecoxib (Celebrex), ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren, Cataflam), and others
100% IV bioavailability
CYP450 enzymes in the liver lead to inactive metabolites.
1.5 to 2 hours for half-life
It is a prescription drug that cannot be purchased over-the-counter. Bumetanide causes the body to pass extra water and salt through the urine, which is how it works. Blood pressure is lowered and swelling is decreased as a result. Depending on the recommended dose, bumetanide is typically taken either once or twice daily.
The drug bumetanide requires a prescription and is not sold over the counter. Bumetanide causes the body to pass extra water and salt through the urine, which is how it works. Blood pressure is lowered and swelling is decreased as a result. Depending on the recommended dose, bumetanide is typically taken either once or twice daily.
Bumetanide's most typical side effects are cramps in the muscles, nausea, and diarrhea. The majority of the time, these side effects are minor and don't need any special care. Allergies, kidney and liver issues, as well as other serious side effects of bumetanide.
Allergic reactions: A severe allergic reaction to bumetanide is possible. Hives, breathing issues, and facial, lip, tongue, or throat swelling are signs of a severe allergic reaction. Call your doctor right away and stop taking bumetanide if you experience any of these symptoms.
Bumetanide has been linked to kidney issues. Reduced urine production, blood in the urine, and swelling in the ankles or feet are all signs of kidney disease.
Bumetanide has been linked to liver issues. Yellowing of the skin or eyes, dark urine, nausea, vomiting, abdominal pain, and fatigue are all signs of liver issues. Your bumetanide treatment may need to be stopped or its dosage adjusted by your doctor.
Dosage and Administration
Adults should begin taking bumetanide at a dose of 0.5 to 1 mg once or twice daily. The maximum daily dose advised is 10 mg. Children aged 6 to 18 years old should begin treatment with 0.1 mg/kg once or twice daily. The recommended daily dose for kids is no more than 2 mg.
1 mg once or twice daily is the suggested starting dose for those with high blood pressure. The maximum daily dose advised is 10 mg.
The starting dose for edema patients is 0.5 mg to 1 mg once or twice daily. The maximum daily dose advised is 10 mg.
Bumetanide should be taken as soon as you remember if you miss a dose.
Contact your doctor or a poison control center right away if you take too much bumetanide. Low blood pressure, an irregular heartbeat, and fainting are all signs of an overdose.
Bumetanide needs to be kept in a dark, dry place at room temperature. Keep it out of the bathroom. Keep bumetanide away from children and animals.