Sereflo Information Disclaimer

Please note that we do not distribute or sell Sereflo. The content provided on this webpage is intended solely for informational and educational purposes. It should not be construed as medical advice, diagnosis, or treatment recommendation. Always consult a qualified healthcare professional for personalised medical advice and treatment options.

Treatment options

Sereflo - welzo
Sereflo - welzo


Sereflo - welzo
Sereflo - welzo
Sale price £36.00
In stock.

Sereflo is a medicated inhaler used to treat severe asthma and other breathing problems. Sereflo effectively relieves...

Sereflo is a medicated inhaler used to treat severe asthma and other breathing problems. Sereflo effectively relieves symptoms while preventing flare-ups of breathlessness and wheezing.

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In stock.


Sereflo for Asthma & Breathing Problems

Asthma and Chronic obstructive pulmonary disease (COPD) are breathing conditions that primarily affect the lungs and can cause a range of breathing difficulties. Asthma often occurs after exposure to a trigger, however, it can happen randomly. Triggers may include common allergies to pollen or animal dander, infections, environmental changes or from exercise.

Sereflo is a prescription medication used to prevent breathing problems such as asthma. This is a daily asthma preventer that can help to stop feelings of breathlessness and wheezing and is not a reliever inhaler.

What is Sereflo and how does it work?

Sereflo is a combination inhaler that contains two medicines: salmeterol and fluticasone propionate. Salmeterol is a long-acting bronchodilator that can help the airways stay open to increase the amount of air travelling through. Fluticasone propionate is a corticosteroid which can reduce the swelling and irritation in the lungs. 

Sereflo is indicated for use in adults aged 18 years of age and older only and is not a reliever/rescue inhaler.

Is Sereflo right for me?

If you are diagnosed with asthma, COPD or other breathing condition, you may be prescribed Sereflo by a doctor or healthcare professional. However, it may not be suitable for you if you have the following:

  • If you are allergic to salmeterol, fluticasone propionate or any other ingredients in this medicine
  • If you have a history of heart problems
  • If you have high blood pressure
  • If you have an overactive thyroid gland
  • If you have diabetes mellitus
  • If you have low potassium in your blood
  • If you have (or have had) Tuberculosis or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), beta-blockers, medicines to treat infections, corticosteroids or other bronchodilators

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects of Sereflo. However, these do not always occur and are mostly mild in nature. But if you experience any prolonged or worrying side effects of Sereflo, please discontinue the medication immediately and consult your doctor.

Common side effects include:

  • Increased number of colds
  • Headaches
  • Thrush in the mouth and throat
  • Sore tongue
  • Hoarse voice and throat irritation
  • Aching, swollen joints and muscle pain
  • Muscle cramps

How to use Sereflo?

Always use Sereflo exactly as prescribed by your doctor or advised by the pharmacist. The recommended starting dose for adults is 2 puffs (25/125) twice a day to relieve asthma, however, in presence of other factors, this may be increased or decreased accordingly as per the prescriber's clinical judgement. 

For adults:

  • To relieve asthma - two puffs twice a day (25/125)


  • Start to breathe as slowly as possible just before using your inhaler
  • Stand or sit upright when using
  • Remove the mouthpiece and inspect it to ensure it is clear of debris and objects
  • Shake the inhaler 4 or 5 times and hold the inhaler upright with your thumb on the base, breathe out
  • Place the mouthpiece in your mouth between your teeth and close your lips, do not bite it
  • Breathe in through your mouth and just after you begin your breath, press down on the top of the canister to release a puff of this medicine whilst still breathing in steadily and deeply
  • Hold your breath and take your inhaler from your mouth, continue holding your breath for a few seconds
  • It can be taken at any time of day, with or without food
  • If you are pregnant or breast-feeding, consult your doctor before using this medicine

Do not use your inhaler more often than the doctor told you to.

Video on how to use a Sereflo Inhaler

Warnings and Precautions

Sereflo may not be safe if taken with other medication or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT use Sereflo:

  • If you are allergic to salmeterol, fluticasone propionate or any other ingredients in this medicine
  • If you have a history of heart problems
  • If you have high blood pressure
  • If you have an overactive thyroid gland
  • If you have diabetes mellitus
  • If you have low potassium in your blood
  • If you have (or have had) Tuberculosis or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), beta-blockers, medicines to treat infections, corticosteroids or other bronchodilators

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!

Product reviews

Please note the information below is intended for general knowledge, please read the patient information leaflet and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

Can I get Sereflo on the NHS?

Whether or not you can get Sereflo on the NHS is dependent on your local guidelines and eligibility status. It is best to contact your local GP service if you are unsure of whether you can get Sereflo from the NHS.

Can you get Sereflo over the counter?

No, you can’t get Sereflo over the counter without a prescription or consultation. Sereflo is a regulated medication so all purchases need to have a prescription and/or suitable consultation form completed.

Can I buy Sereflo online even if I have never taken it before?

A prescribing pharmacist will need to review your consultation form before the medication can be dispatched.

Is Sereflo safe?

If you have been prescribed Sereflo then it is at the discretion of the prescriber.

However, all medications can potentially have adverse effects and should be taken exactly as prescribed. If you experience any side effects when taking Sereflo then you should contact a doctor immediately.

Are there any foods that should be avoided when taking Sereflo?

We recommend you read the patient information leaflet for this product thoroughly before taking the treatment. This is essential to understanding any interactions that can occur and to take the medication safely.

Can I buy Sereflo from Boots?

It is generally possible to purchase medication, including Sereflo, from UK pharmacies like Boots. However, I recommend checking the Boots website or contacting Boots directly for the most current and accurate information. Remember to consult with a healthcare professional before starting any new medication.

Can I buy Sereflo from Superdrug?

If you would like to buy Sereflo, you will need to check availability on the Superdrug website.

Can I buy Sereflo from Amazon?

Amazon does not sell medication such as Sereflo, as they are not a pharmacy service provider. Always check with Amazon to see what they sell.

How long does Sereflo take to work?

The time it takes for a Sereflo to work can vary greatly depending on several factors, such as the strength, the individual's age, weight, and overall health, as well as any potential interactions with other medications or substances. Generally, the effects of Sereflo may be noticeable within the time frame outlined by the prescribing pharmacist. It is important to follow the prescribed dosage and instructions provided by your healthcare professional, and to consult them if you have any concerns or questions about the medication's efficacy or possible side effects.

How effective is Sereflo?

The effectiveness of Sereflo can vary significantly depending on various factors, such as the dosage, the condition being treated, the individual's age, weight, and overall health, as well as the presence of any other medications or substances that might interact with it. While some medications may be highly effective for certain individuals and conditions, others might experience a lesser degree of benefit or may require adjustments to the dosage or additional treatments to achieve the desired results.

What are the risks of taking Sereflo?

At Welzo, we are dedicated to providing our customers with accurate and comprehensive information about medications. We believe that understanding the potential risks and side effects associated with a medication is essential for making informed decisions about your health. This guide outlines some general considerations for assessing the risks of medication and includes references to the National Health Service (NHS) for further information.

  1. Read the Patient Information Leaflet (PIL): Every medication comes with a Patient Information Leaflet, which provides essential details about the drug, its uses, and potential side effects. Be sure to read this leaflet carefully before starting any new medication. The Electronic medicines compendium has a list of patient leaflets. you can visit by heading to
  2. Be aware of potential side effects: All medications have the potential to cause side effects, ranging from mild and short-lived symptoms to more serious, long-lasting issues. It's important to understand the possible side effects of a medication and how to manage them. The NHS has a helpful resource on managing medication side effects, while also speaking to a healthcare professional is important in understanding any potential risks of taking Sereflo.
  3. Interactions with other medications: Some medications may interact with others, leading to increased side effects or reduced effectiveness. Make sure to inform your healthcare professional about all the medications and supplements you are currently taking. The NHS offers a useful tool for checking potential drug interactions here.
  4. Contraindications and precautions: Certain medical conditions or factors may make it unsafe for you to take a particular medication. Before starting any new medication, inform your healthcare professional about your medical history and any current health issues. The NHS provides more information about contraindications and precautions here.
  5. Appropriate use and dosage: It's crucial to follow the prescribed dosage and instructions for taking a medication to ensure its effectiveness and minimise the risk of side effects. The NHS has a useful guide on using medicines safely here.
  6. Monitoring and follow-up: Some medications require regular monitoring or follow-up appointments with your healthcare professional to ensure their safety and effectiveness. Be sure to schedule and attend these appointments as needed.

Can I buy Sereflo in the UK?

Yes, you can buy Sereflo in the UK with a valid prescription and or consultation form. Sereflo is available in the UK for purchase from local pharmacies with a valid prescription and or consultation. It is imperative that you ensure that the pharmacy you are buying the products from is licensed and registered with the General Pharmaceutical Council (GPhC).

Are Sereflo users satisfied with the product?

We have a list of reviews from customers taking Sereflo at the bottom of this page. For more information of the reviews of Sereflo head over to for further details.

Can I buy Sereflo from an online pharmacy?

This is dependent on your eligibility for the medication.

How much does Sereflo cost?

The costs of Sereflo are listed at the top of the page. Pricing is provided as a reference as we do not sell Sereflo.

What type of inhaler is Sereflo?

Sereflo is a daily preventer and combination inhaler as it should be used every day to prevent and treat symptoms of asthma.

Can you use Sereflo if you are pregnant or breastfeeding?

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. 

When should you not take Sereflo?

Talk to your doctor before using Sereflo if you have:

  • Heart disease, including an irregular or fast heart beat
  • Overactive thyroid gland
  • High blood pressure
  • Diabetes mellitus (Sereflo may increase your blood sugar)
  • Low potassium in your blood
  • Tuberculosis (TB) now, or in the past, or other lung infections 

What happens if I stop using Sereflo?

It is very important that you take your Sereflo every day as directed. Keep taking it until your doctor tells you to stop. Do not stop or suddenly reduce your dose of Sereflo. This could make your breathing worse.

In addition, if you suddenly stop taking Sereflo or reduce your dose of Sereflo this may (very rarely) cause you to have problems with your adrenal gland (adrenal insufficiency) which sometimes causes side effects. These side effects may include any of the following:

  • Stomach pain
  • Tiredness and loss of appetite, feeling sick
  • Sickness and diarrhoea
  • Weight loss
  • Headache or drowsiness
  • Low levels of sugar in your blood
  • Low blood pressure and seizures (fits)

Customer Reviews

Based on 2 reviews
Viva Toelkes

The customer service at is always polite and helpful. They are very responsive to any issues or concerns.

Refugia Jacobos

I'm extremely satisfied with my purchase of Sereflo. It's easy to use and has significantly improved my breathing issues. Highly recommended for anyone dealing with respiratory problems.