Treatment options

  • Next day delivery
  • Discreet & confidential
  • UK licensed medication
Sereflo - welzo
Sereflo - welzo
Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
14 Reviews
In stock.

Sereflo is a medicated inhaler used to treat severe asthma and other breathing problems. Sereflo effectively relieves symptoms while preventing flare-ups of breathlessness and wheezing.

Free delivery by Tomorrow, April 27.
Order within
Pricing is provided as a reference. Treatment will be shown after completing the consultation. The final decision on issuing this medication remains with the prescriber.
Secure Transaction
In stock.
As seen in
100% UK-based pharmacies
Our team of doctors, network of pharmacy suppliers and our support staff, are all UK-based.
Free advice and support
Have a question? Email support is always free; Monday - Friday, 9am - 5pm.
Free UK delivery over £40
Fast, securely delivered, tracked next-day United Kingdom delivery from £3.99. Or free when over £40.
We’re rated 4.9 out of 5
Based on over 24,000+ reviews on Trustindex, Trustpilot and Google.
Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
As seen in


Sereflo for Asthma & Breathing Problems

Asthma and Chronic obstructive pulmonary disease (COPD) are breathing conditions that primarily affect the lungs and can cause a range of breathing difficulties. Asthma often occurs after exposure to a trigger, however, it can happen randomly. Triggers may include common allergies to pollen or animal dander, infections, environmental changes or from exercise.

Sereflo is a prescription medication used to prevent breathing problems such as asthma. This is a daily asthma preventer that can help to stop feelings of breathlessness and wheezing and is not a reliever inhaler.

What is Sereflo and how does it work?

Sereflo is a combination inhaler that contains two medicines: salmeterol and fluticasone propionate. Salmeterol is a long-acting bronchodilator that can help the airways stay open to increase the amount of air travelling through. Fluticasone propionate is a corticosteroid which can reduce the swelling and irritation in the lungs. 

Sereflo is indicated for use in adults aged 18 years of age and older only and is not a reliever/rescue inhaler.

Is Sereflo right for me?

If you are diagnosed with asthma, COPD or other breathing condition, you may be prescribed Sereflo by a doctor or healthcare professional. However, it may not be suitable for you if you have the following:

  • If you are allergic to salmeterol, fluticasone propionate or any other ingredients in this medicine
  • If you have a history of heart problems
  • If you have high blood pressure
  • If you have an overactive thyroid gland
  • If you have diabetes mellitus
  • If you have low potassium in your blood
  • If you have (or have had) Tuberculosis or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), beta-blockers, medicines to treat infections, corticosteroids or other bronchodilators

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects of Sereflo. However, these do not always occur and are mostly mild in nature. But if you experience any prolonged or worrying side effects of Sereflo, please discontinue the medication immediately and consult your doctor.

Common side effects include:

  • Increased number of colds
  • Headaches
  • Thrush in the mouth and throat
  • Sore tongue
  • Hoarse voice and throat irritation
  • Aching, swollen joints and muscle pain
  • Muscle cramps

How to use Sereflo?

Always use Sereflo exactly as prescribed by your doctor or advised by the pharmacist. The recommended starting dose for adults is 2 puffs (25/125) twice a day to relieve asthma, however, in presence of other factors, this may be increased or decreased accordingly as per the prescriber's clinical judgement. 

For adults:

  • To relieve asthma - two puffs twice a day (25/125)


  • Start to breathe as slowly as possible just before using your inhaler
  • Stand or sit upright when using
  • Remove the mouthpiece and inspect it to ensure it is clear of debris and objects
  • Shake the inhaler 4 or 5 times and hold the inhaler upright with your thumb on the base, breathe out
  • Place the mouthpiece in your mouth between your teeth and close your lips, do not bite it
  • Breathe in through your mouth and just after you begin your breath, press down on the top of the canister to release a puff of this medicine whilst still breathing in steadily and deeply
  • Hold your breath and take your inhaler from your mouth, continue holding your breath for a few seconds
  • It can be taken at any time of day, with or without food
  • If you are pregnant or breast-feeding, consult your doctor before using this medicine

Do not use your inhaler more often than the doctor told you to.

Video on how to use a Sereflo Inhaler

Warnings and Precautions

Sereflo may not be safe if taken with other medication or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT use Sereflo:

  • If you are allergic to salmeterol, fluticasone propionate or any other ingredients in this medicine
  • If you have a history of heart problems
  • If you have high blood pressure
  • If you have an overactive thyroid gland
  • If you have diabetes mellitus
  • If you have low potassium in your blood
  • If you have (or have had) Tuberculosis or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), beta-blockers, medicines to treat infections, corticosteroids or other bronchodilators

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!

Product reviews

How it works
Complete a Quick & Free Online Consultation

This is a quick process and should only take 1 - 2 minutes. All of your answers are confidential, and just like a GP consultation, you will know what treatment is most suitable for you instantly upon completion.

Place Your Order for Sereflo

Once you have completed the quick online form, select the treatment option most suitable to you and checkout securely.

Express Next Day Delivery

A medical professional will review your answers to the online medical consultation and determine if it’s safe to prescribe and what treatments are available.

Sereflo Asthma Treatment

What is Sereflo?

Sereflo is a proprietary medication formulated for the treatment of chronic obstructive pulmonary diseases (COPD) and asthma. The therapeutic tool is a combination inhaler that contains two active ingredients: fluticasone propionate, a corticosteroid, and salmeterol, a long-acting bronchodilator. It functions by reducing inflammation in the lungs and widening the airways, facilitating individuals with respiratory disorders to breathe more efficiently.

How does Sereflo work?

The dual-action mechanism of Sereflo is quite fascinating, Fluticasone propionate, one of the active ingredients, boasts anti-inflammatory properties. It penetrates the cells lining the airways in the lungs, reducing the release of certain chemicals associated with inflammatory responses. The process decreases swelling and inflammation in the lungs, which in turn aids breathing.

On the other hand, salmeterol works by stimulating receptors known as beta2-adrenoceptors in the lungs. When these receptors are activated, the muscles of the airways relax, causing the airways to open. The action is termed bronchodilation, and it enables easier passage of air in and out of the lungs.

What class of medication is a Seroflo inhaler?

Seroflo belongs to a class of medications known as combination corticosteroids and bronchodilator inhalers. The combination and class of drugs are well-regarded for their effectiveness in managing conditions like asthma and COPD where both inflammation and constriction of the airways are involved.

What is the role of each active ingredient in Seroflo?

Seroflo comprises two active ingredients: fluticasone propionate and salmeterol. Fluticasone propionate is a corticosteroid that acts on the inflammatory response in the body. It restricts the release of inflammation-causing substances, thus reducing inflammation and swelling in the lungs.

Salmeterol, the second ingredient, is a long-acting bronchodilator. It is responsible for relaxing and opening the airways to the lungs, aiding the individual in breathing more comfortably. 

Together, these two ingredients provide a comprehensive approach to managing the symptoms of conditions like asthma and COPD.

Is Seroflo the same as Seretide?

No, although similar Seroflo and Seretide are not exactly the same. Seroflo and Seretide are very similar in that they both contain the same active ingredients – fluticasone propionate and salmeterol. The difference between them mainly lies in the branding; they are marketed under different names by different companies. Thus, Seroflo and Seretide function in similar ways, and might be considered therapeutic equivalents.

Sereflo Dosage & Usage

Sereflo dosage

The specific dosage of Seroflo varies depending on the patient's condition and the severity of symptoms. The standard dose for adults and adolescents over 12 years of age is two puffs from the Seroflo inhaler twice a day. However, it's essential to follow the exact dosage instructions given by a healthcare professional.

Can I take Seroflo every day?

Yes, Seroflo is designed for regular use and must be taken as prescribed by a healthcare professional. Consistent use helps maintain open airways and prevent asthma or COPD symptoms. However, it is important not to exceed the prescribed dosage, as it might lead to adverse effects.

How do I use Sereflo?

To use Seroflo, one must first remove the cap from the mouthpiece of the inhaler. Breathe out as far as is comfortable, then place the mouthpiece in the mouth, with the lips creating a tight seal around it. As one begins to breathe in slowly and deeply, press down on the top of the inhaler to release a dose of the medication. Continue to breathe in as slowly as possible until the lungs are full, then hold the breath for about ten seconds, or as long as is comfortable.

What should I do if I miss a dose or overdose on Seroflo?

In case of a missed dose, one must take it as soon as they remember. However, if it's close to the time for the next dose, skip the missed one and continue with the regular schedule. One must not double dose to make up for the missed one.

If an overdose is suspected, it's crucial to seek medical help immediately. Overdosing on Seroflo might lead to serious complications like a fast or irregular heartbeat, weakness, shakiness or palpitations.

Is Seroflo suitable for children and the elderly?

Seroflo is not suitable for children under 12 years of age and may cause complications in some elderly people, following recommendations from a healthcare provider. Seroflo is generally safe for use by the elderly under the guidance of a healthcare professional, however, it's worth noting that the elderly might be more susceptible to side effects.

As for children, the use of Seroflo must be determined by a healthcare professional. Children under 12 years must not usually use Seroflo, but it is potentially prescribed in specific circumstances. It's crucial to follow all dosage instructions carefully to ensure the medication is used safely and effectively.

Sereflo Side Effects & Considerations

What are the side effects of Sereflo?

Like any medication, Sereflo might cause side effects, however, not everyone experiences them. Some common side effects include headaches, a sore throat or throat irritation, and thrush in the mouth and throat. Less common side effects encompass muscle cramps, palpitations, or an unexpected increase in wheezing or shortness of breath immediately after using the inhaler. It is important to note that these are typically transient and might disappear as the body adjusts to the medication.

Who should not use Seroflo?

Individuals with certain conditions must avoid using Sereflo, conditions include hypersensitivity to fluticasone, salmeterol, or any component of the inhaler. People with severe liver disease, tuberculosis, viral, fungal, or other untreated infections must consult a healthcare professional before starting on Seroflo.

Can Seroflo cause an allergic reaction? What are the signs?

Yes, like all medicines, Seroflo might cause allergic reactions in some individuals, though it is rare. Signs of an allergic reaction include a rash, itching or hives on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or difficulty breathing. If any of these signs are noticed after using Seroflo, medical attention must be sought immediately.

Is Seroflo a steroid inhaler?

Yes, Seroflo is a combination inhaler that contains fluticasone propionate, which is a type of steroid. Fluticasone propionate helps to reduce inflammation in the lungs.

Can Seroflo be used during pregnancy or while breastfeeding?

The use of Seroflo during pregnancy or while breastfeeding must only occur if the benefit outweighs the potential risk to the baby and as recommended by a provider. A healthcare professional must be consulted before using the medication if one is pregnant, planning to become pregnant, or breastfeeding.

Does Seroflo have any effects on driving or operating heavy machinery?

No, Seroflo is not typically known to impair one's ability to drive or operate heavy machinery. However, as with any medication, it's recommended to see how one reacts to Seroflo before undertaking these activities. If a person experiences side effects like dizziness or blurred vision, they must avoid these activities until such side effects subside.

Sereflo Availability & Pricing

How do I buy Sereflo online?

To buy Sereflo online, one must look for trusted online pharmacies. Start by searching for the medication on the pharmacy website, then select the desired quantity and strength, and add it to the shopping cart. In most cases, a valid prescription from a healthcare professional is needed to complete the purchase. After the checkout process, the medication is delivered to the given address.

How should Seroflo be stored?

Seroflo must be stored in a cool, dry place, away from direct heat and light. The ideal storage temperature is below 30 degrees Celsius. The inhaler must be kept clean and dry, and the cap must be replaced after each use. It's important to keep it out of sight and reach of children.

Sereflo Alternatives

What is Sereflo 25 250 equivalent to?

Sereflo 25/250 is equivalent to medications that contain the same amounts of fluticasone propionate (250mcg) and salmeterol (25mcg). These include Seretide 25/250 and the generic version of the medication.

What is the generic version of Seroflo?

The generic version of Seroflo contains the same active ingredients, fluticasone and salmeterol. It is marketed under different names depending on the country and pharmaceutical company.

Seroflo 250 inhaler alternative

Alternatives to the Seroflo 250 inhaler are those that contain the same active ingredients: fluticasone and salmeterol, including Seretide, Advair, and AirFluSal Forspiro. However, discussing with a healthcare professional before changing medications is always recommended.

Seroflo vs Seretide

Seroflo and Seretide are similar in that they both contain the same active ingredients – fluticasone and salmeterol. They are effectively the same medication but are marketed under different names by different companies. They work in the same way to reduce inflammation and widen the airways, helping individuals with asthma or COPD to breathe more easily.

Buy Sereflo Online

Please note the information below is intended for general knowledge, please read the patient information leaflet and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

You can buy Sereflo online from our UK-registered online pharmacy partners. Complete an online consultation form and our system will show you if you are eligible to purchase Sereflo online. Our pharmacists will then review your order of Sereflo and dispatch it discreetly to your address.

How to buy Sereflo online?

You can buy Sereflo by following the following steps.

  1. Fill out our online consultation form
  2. If you are eligible to purchase Sereflo you will be shown it as one of your treatment options
  3. Pay online and receive your order to the comfort of your chosen address

Can I get Sereflo on the NHS?

Whether or not you can get Sereflo on the NHS is dependent on your local guidelines and eligibility status. It is best to contact your local GP service if you are unsure of whether you can get Sereflo from the NHS.

Can you get Sereflo over the counter?

No, you can’t get Sereflo over the counter without a prescription or consultation. Sereflo is a regulated medication so all purchases need to have a prescription and/or suitable consultation form completed.

Can I buy Sereflo online even if I have never taken it before?

A prescribing pharmacist will need to review your consultation form before the medication can be dispatched. One of our partner prescribing pharmacists will review the consultation form and will decide if you are eligible to buy Sereflo.

Is Sereflo safe?

If you have been prescribed Sereflo then it is at the discretion of the prescriber.

However, all medications can potentially have adverse effects and should be taken exactly as prescribed. If you experience any side effects when taking Sereflo then you should contact a doctor immediately.

Are there any foods that should be avoided when taking Sereflo?

We recommend you read the patient information leaflet for this product thoroughly before taking the treatment. This is essential to understanding any interactions that can occur and to take the medication safely.

Can I buy Sereflo from Boots?

It is generally possible to purchase medication, including Sereflo, from UK pharmacies like Boots. However, I recommend checking the Boots website or contacting Boots directly for the most current and accurate information. Remember to consult with a healthcare professional before starting any new medication.

Can I buy Sereflo from Superdrug?

If you would like to buy Sereflo, you will need to check availability on the Superdrug website.

Can I buy Sereflo from Amazon?

Amazon does not sell medication such as Sereflo, as they are not a pharmacy service provider. Always check with Amazon to see what they sell.

How long does Sereflo take to work?

The time it takes for a Sereflo to work can vary greatly depending on several factors, such as the strength, the individual's age, weight, and overall health, as well as any potential interactions with other medications or substances. Generally, the effects of Sereflo may be noticeable within the time frame outlined by the prescribing pharmacist. It is important to follow the prescribed dosage and instructions provided by your healthcare professional, and to consult them if you have any concerns or questions about the medication's efficacy or possible side effects.

How effective is Sereflo?

The effectiveness of Sereflo can vary significantly depending on various factors, such as the dosage, the condition being treated, the individual's age, weight, and overall health, as well as the presence of any other medications or substances that might interact with it. While some medications may be highly effective for certain individuals and conditions, others might experience a lesser degree of benefit or may require adjustments to the dosage or additional treatments to achieve the desired results.

What are the risks of taking Sereflo?

At Welzo, we are dedicated to providing our customers with accurate and comprehensive information about medications. We believe that understanding the potential risks and side effects associated with a medication is essential for making informed decisions about your health. This guide outlines some general considerations for assessing the risks of medication and includes references to the National Health Service (NHS) for further information.

  1. Read the Patient Information Leaflet (PIL): Every medication comes with a Patient Information Leaflet, which provides essential details about the drug, its uses, and potential side effects. Be sure to read this leaflet carefully before starting any new medication. The Electronic medicines compendium has a list of patient leaflets. you can visit by heading to
  2. Be aware of potential side effects: All medications have the potential to cause side effects, ranging from mild and short-lived symptoms to more serious, long-lasting issues. It's important to understand the possible side effects of a medication and how to manage them. The NHS has a helpful resource on managing medication side effects, while also speaking to a healthcare professional is important in understanding any potential risks of taking Sereflo.
  3. Interactions with other medications: Some medications may interact with others, leading to increased side effects or reduced effectiveness. Make sure to inform your healthcare professional about all the medications and supplements you are currently taking. The NHS offers a useful tool for checking potential drug interactions here.
  4. Contraindications and precautions: Certain medical conditions or factors may make it unsafe for you to take a particular medication. Before starting any new medication, inform your healthcare professional about your medical history and any current health issues. The NHS provides more information about contraindications and precautions here.
  5. Appropriate use and dosage: It's crucial to follow the prescribed dosage and instructions for taking a medication to ensure its effectiveness and minimise the risk of side effects. The NHS has a useful guide on using medicines safely here.
  6. Monitoring and follow-up: Some medications require regular monitoring or follow-up appointments with your healthcare professional to ensure their safety and effectiveness. Be sure to schedule and attend these appointments as needed.

Can I buy Sereflo in the UK?

Yes, you can buy Sereflo in the UK with a valid prescription and or consultation form. Sereflo is available in the UK for purchase from local pharmacies with a valid prescription and or consultation and to purchase from Welzo if in stock. It is imperative that you ensure that the pharmacy you are buying the products from is licensed and registered with the General Pharmaceutical Council (GPhC).

Where can I buy Sereflo?

You can buy Sereflo online from upon completion of a consultation form and a free review from a prescribing pharmacist.

Are Sereflo users satisfied with the product?

We have a list of reviews from customers taking Sereflo at the bottom of this page. For more information of the reviews of Sereflo head over to for further details.

Can I buy Sereflo from an online pharmacy?

Yes, you can purchase Sereflo from an online pharmacy. However, this is dependent on your eligibility for the medication.

How much does Sereflo cost?

The costs of Sereflo are listed at the top of the page. Pricing is provided as a reference as treatment options will be shown upon completing the consultation form.

What type of inhaler is Sereflo?

Sereflo is a daily preventer and combination inhaler as it should be used every day to prevent and treat symptoms of asthma.

Can you use Sereflo if you are pregnant or breastfeeding?

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. 

When should you not take Sereflo?

Talk to your doctor before using Sereflo if you have:

  • Heart disease, including an irregular or fast heart beat
  • Overactive thyroid gland
  • High blood pressure
  • Diabetes mellitus (Sereflo may increase your blood sugar)
  • Low potassium in your blood
  • Tuberculosis (TB) now, or in the past, or other lung infections 

What happens if I stop using Sereflo?

It is very important that you take your Sereflo every day as directed. Keep taking it until your doctor tells you to stop. Do not stop or suddenly reduce your dose of Sereflo. This could make your breathing worse.

In addition, if you suddenly stop taking Sereflo or reduce your dose of Sereflo this may (very rarely) cause you to have problems with your adrenal gland (adrenal insufficiency) which sometimes causes side effects. These side effects may include any of the following:

  • Stomach pain
  • Tiredness and loss of appetite, feeling sick
  • Sickness and diarrhoea
  • Weight loss
  • Headache or drowsiness
  • Low levels of sugar in your blood
  • Low blood pressure and seizures (fits)
Why Welzo
Discreet next day shipping
Discreet next day shipping

Welzo prescription medication is shipped out for next-day delivery in discreet packaging.

Trusted UK Pharmacy
Trusted UK Pharmacy

Welzo only works with UK-based pharmacies. All our medication is authentic and issued by GPhC-registered pharmacies and prescribers.

Supportive & Caring
Supportive & Caring

Our team of clinicians and health experts can support you along every step of your treatment journey.

Why Welzo

Customer Reviews