Health Benefits of Provigil
The medication Provigil (modafinil) encourages wakefulness. It is believed to function by modifying the brain's natural chemicals (neurotransmitters).
Narcolepsy, shift work sleep disorder, and sleep apnea are all conditions that are treated with Provigil.
The use of Provigil is not limited to those conditions detailed in this medication guide.
Users of Welzo can use this article for informational purposes to better understand Provigil.
Side Effects of Provigil
The most typical Provigil side effects include:
a lack of sleep (insomnia),
On some urine drug tests, provigil may result in false positive results. Inform the lab staff that you take modafinil if you submit a urine sample for drug testing.
Skin blistering, burning, crusting, dryness, or flaking are extremely uncommon (less than 0.01%).
Infrequent occurrence: Skin rashes caused by allergies, including Stevens-Johnson syndrome and toxic epidermal necrolysis
Call your doctor right away if you experience any of the following side effects:
- suicidal or self-destructive thoughts
- heart palpitations or erratic heartbeat
- swelling in the ankles or legs
- breathing difficulty
- yellowing of the eyes or skin
There may be additional side effects; this is not a comprehensive list.
Dosage of Provigil
Provigil is typically prescribed in doses of 200 mg once daily.
The suggested dose is 200 mg taken orally once daily as a single dose in the morning for people with OSA or narcolepsy.
For those who have SWD, a dose of 400 mg taken orally once daily, one hour before the start of their work shift, is advised.
If you have a modafinil or armodafinil (Nuvigil) allergy, you should avoid taking this medication.
Inform your doctor of any of the following to ensure that modafinil is safe for you:
- depression, anxiety, or thoughts of suicide;
- kidney illness;
- hypertension, cardiovascular disease, or a history of heart attacks;
mental health issues; or
- abusing or being dependent on nicotine, drugs, or alcohol.
It is unlikely that modafinil will hurt an unborn child. If you are pregnant or intend to become pregnant, let your doctor know.
If modafinil enters breast milk or if it could harm a nursing infant are unknown. Using this medication while nursing is not advised.
Without consulting a doctor, never administer this medication to anyone under the age of 18.
Interactions with Provigil
It's possible for modafinil to interact with other drugs. Inform your doctor about all prescription, over-the-counter, and dietary supplements you are taking. Tell your doctor right away if you take:
- antidepressants like fluoxetine (Prozac, Sarafem, Symbyax), paroxetine (Brisdelle, Paxil, Pexeva), citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), or sertraline (Zoloft);
- contraceptive pills;
the drug clozapine (FazaClo);
cyclosporine (Gengraf, Neoral, and Sandimmune);
- Lanoxin, or digoxin
- Lariam (mefloquine);
- Versed (midazolam), or
rifampin (brand names: Rimadin, Rimactane).
Mechanism of Action
It is unclear how precisely Provigil works. The brain's neurotransmitters, which nerves use to communicate with one another, are thought to be modulated in order for it to function.
Due to its potential for abuse and dependence, Provigil is classified as a schedule IV controlled substance.
Only use Provigil according to your doctor's recommendations. Observe all guidelines provided on the prescription label. Never take more or less of this medication than is advised, or for an extended period of time.
Modafinil is quickly absorbed when taken orally. Modafinil tablets have a bioavailability rate of about 80%.
The liver uses the CYP3A4 isoenzyme to break down modafinil, which is then excreted in the urine as modafinil acid. After multiple doses, modafinil's elimination half-life is approximately 15 hours.
Alternatives to Provigil
There are numerous drugs that can be used instead of Provigil. These include additional wakefulness-inducing substances like caffeine and armodafinil (Nuvigil).
There's a chance that some people will encounter unlisted side effects. If you experience any symptoms while taking this medication that worry you, speak with your doctor.