Unlock the potential for enhanced mood and cognitive function with Jarrow Formulas SAMe 400, a supplement meticulously crafted to support brain, joint, and liver health. Each tablet delivers 400 mg of SAMe (net yield) derived from 800 mg of SAMe tosylate disulfate. Manufactured under low temperature and humidity conditions, these enteric-coated tablets ensure maximum biological activity and absorption.

SAMe, a crucial metabolite of the essential amino acid methionine, is available in two forms: (S,S) and (R,S). The (S,S) form is the biologically active structure, while the (R,S) form is inactive. Jarrow Formulas SAMe is produced through microbiological fermentation, maintaining 68-80% of the active (S,S) SAMe without chemical solvents, ensuring superior bioavailability.

Supporting brain metabolism and mood, SAMe is involved in methylation reactions that synthesize phosphatidylcholine, a key component of brain grey matter and cellular membranes. It also aids in neurotransmitter metabolism, promoting a balanced mood. For joint health, SAMe supports the production of healthy connective tissue by sulfating glycosaminoglycans (GAGs) like glucosamine and chondroitin. Additionally, SAMe enhances liver function by aiding in the synthesis of glutathione (GSH), a critical antioxidant for liver detoxification processes. Choose Jarrow Formulas SAMe 400 for a scientifically-backed supplement that supports your overall health.

Microcrystalline cellulose, coating (hypromellose acetate succinate, stearic acid [vegetable source], triethyl citrate and riboflavin), glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate.

Please refer to the product packaging label for the most accurate and up-to-date information regarding ingredients. It is crucial to review all ingredients on the product packaging itself carefully to ensure they align with your dietary needs and restrictions. Welzo cannot be held responsible for any discrepancies or allergen information on the website as the information is not always accurate.

UK, Europe & Rest of the World Shipping Details:
Same day dispatch for orders placed by 2pm (Orders after 2pm dispatched next working day).

Free shipping on orders over £45 to the UK.

Returns: Our supplements are meant to make you feel healthy and at your best. If you need to return your item, you can do so free of charge within 14 days in the same original and unopened packaging.

Take 1 tablet of Jarrow Formulas SAMe 400 daily on an empty stomach, or as directed by your qualified healthcare professional. Store in a cool, dry place. Keep out of reach of children. Consult a doctor before use if you are taking prescribed medications such as antidepressants, have Parkinson's disease, bipolar disorder, or are pregnant or breastfeeding. Do not exceed the recommended dose. Discontinue use and consult a doctor if any unwanted reactions occur.

Please consult the product packaging for accurate instructions on how to use the product. Welzo is not liable for any discrepancies or errors on the website. Always follow the directions on the packaging to ensure proper use.