Moduretic
A drug called moduretic is used to treat edema and hypertension, or high blood pressure. It combines the medications hydrochlorothiazide and amiloride. Amiloride prevents your body from absorbing too much salt, which can lead to fluid retention, and this is how it works. A "water pill" (diuretic) called hydrochlorothiazide makes you produce more urine, which aids in your body's elimination of surplus salt and water. Welzo users can use the information in this article to learn more about Moduretic.
Health Benefits
Edema and high blood pressure (hypertension) can both be treated with moduretic.
Your body retains too much fluid, which is a condition known as fluid retention. Your hands, feet, ankles, or lower legs may swell as a result.
When you have high blood pressure, your blood pushes too hard against the walls of your arteries. Your heart may feel the strain, and your arteries may become damaged. Kidney failure, heart disease, and stroke can all be caused by high blood pressure.
Moduretic can be utilized for other conditions not covered in this medication guide.
Side Effects & Safety
Moduretic side effects may be severe. If you experience any of the following symptoms of an allergic reaction, contact your doctor right away: hives; trouble breathing; swelling of your face, lips, tongue, or throat.
If you experience any of these dangerous side effects, call your doctor right away:
a pounding or rapid heartbeat;
feeling as though you might faint;
hardly any urination;
your feet or ankles are swollen;
breathing difficulty and coughing up blood;
jaundice, which causes your skin oreyes to turn yellow; or
high potassium (slow heartbeat, sluggish pulse, weak muscles, tingly sensation).
High potassium levels can result from moduretics. If you have additional medical conditions that affect your potassium levels, this effect could be dangerous. If these side effects are minor, they might disappear in a couple of days.
Dosage
Moduretic side effects may be severe. If you experience any of the following symptoms of an allergic reaction, contact your doctor right away: hives; trouble breathing; swelling of your face, lips, tongue, or throat.
If you experience any of these dangerous side effects, call your doctor right away:
a pounding or rapid heartbeat;
feeling as though you might faint;
hardly any urination;
your feet or ankles are swollen;
breathing difficulty and coughing up blood;
jaundice, which causes your skin oreyes to turn yellow; or
high potassium (slow heartbeat, sluggish pulse, weak muscles, tingly sensation).
High potassium levels can result from moduretics. If you have additional medical conditions that affect your potassium levels, this effect could be dangerous. If these side effects are minor, they might disappear in a couple of days.
Interactions
If you take any other medications, herbs, or vitamins, moduretic may interact with them. When a substance modifies how a drug functions, there is an interaction. This could be harmful or stop the medication from working properly.
Your doctor needs to carefully monitor all of your medications to help you avoid interactions. Tell your doctor about all prescription drugs, over-the-counter remedies, and vitamins you are taking. Speak with your doctor or pharmacist to learn how this medication may interact with other medications you are taking.
The following is a list of some medications that may interact with moduretic.
Relationships with Other Drugs
Lithium, digoxin, diuretics, and other blood pressure medications can all interact with moduretic.
Herbal and dietary supplement interactions
Herbs and supplements like can interact with the moduretic.
Mechanism of Action
Diuretics include moduretic. Your body can eliminate extra water and salt with the aid of diuretics.
In order to lower blood pressure, the combination of amiloride and hydrochlorothiazide in Moduretic causes your kidneys to eliminate extra fluid from your body. Additionally, it aids in preventing your body from absorbing too much salt.
Pharmacokinetics
Moduretic is quickly and fully absorbed from the digestive system. Amiloride reaches its mean peak plasma concentration in 1 to 2 hours, while hydrochlorothiazide does so in 3 to 4 hours.
Half-Life
Moduretic has a half-life of around 20 hours.