Peganone might have negative effects. The most typical side effects are as follows:
Among the less frequent side effects are:
suppression of the bone marrow
Stevens-Johnson syndrome, agranulocytosis, aplastic anemia, and exfoliative dermatitis are examples of uncommon side effects. In the event that you encounter any of these side effects, please contact emergency services right away.
Peganone's starting dose is typically 10-15 mg/kg/day split into 2-3 doses. 20–40 mg/kg/day is the desired maintenance dose. To control your seizures, your healthcare provider may change your dose as necessary.
Take the missed Peganone dose as soon as you remember and carry on with your regular dosing schedule. Skip the missed dose and carry on with your regular dosing schedule if it is almost time for your next dose. Never take two Peganone doses at the same time.
Peganone may have interactions with other drugs. All of the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, should be disclosed to your healthcare provider. The following medicines may interact with peganone:
These interactions could make Peganone less effective or raise the possibility of side effects. Your doctor might need to change your dosage or keep a closer eye out for any side effects. Never begin or stop taking any medication without first consulting your healthcare provider.
Mechanism of Action
Peganone functions by raising the concentrations of specific brain chemicals that aid in seizure prevention. Neurotransmitters are the name for these substances. Signals between nerve cells are transmitted by neurotransmitters. Seizures and other conditions can result from a neurotransmitter imbalance. Peganone assists in reestablishing the neurotransmitter balance in the brain, thereby assisting in the prevention of seizures.
Peganone's exact mode of action is not known. To stabilize electrical activity, sodium channels in the brain are thought to be blocked in order for it to work.
The digestive system quickly and completely absorbs peganone. Its half-life is between 12 and 24 hours and it is metabolized in the liver. Peganone is eliminated through the feces and urine.