Where to inject Saxenda? A Step by Step Guide

Where to inject Saxenda? A Step by Step Guide

Understanding Subcutaneous Injection

What Does Subcutaneous Mean?

Subcutaneous refers to the method of administering medication by injecting it into the fatty layer of tissue that sits just beneath the skin. Unlike intramuscular injections that go into the muscle or intravenous injections into the bloodstream, subcutaneous injections have a slower absorption rate. "Subcutaneous injections are often less painful and simpler to administer than other types of injections," states Dr. Peter Lawson, a general practitioner with expertise in diabetes management.

Why Saxenda is Administered Subcutaneously

Saxenda is administered subcutaneously for a couple of key reasons. First, the subcutaneous layer, being fatty, serves as a natural reservoir for the medication, allowing for slow, consistent absorption into the bloodstream. This helps in maintaining more stable blood levels of the medication. "The slow and steady release of Saxenda is crucial for its efficacy in appetite regulation and weight loss," says Dr. Emily Stevens, an endocrinologist.

What is Saxenda?

Brief Overview of Saxenda as a Prescription Medication

Saxenda is a prescription medication used for weight management and is often prescribed for those who have a Body Mass Index (BMI) above 30. It also has applications in the management of Type 2 diabetes. The active ingredient in Saxenda is liraglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist. "Liraglutide mimics a natural hormone in the gut, and when administered in higher doses, helps to regulate appetite and body weight," notes Dr. Sarah Wilson, a dietician and medical consultant.

Indications for Use

Before being prescribed Saxenda, patients typically have a thorough medical evaluation. The medication is specifically indicated for adults who are either obese or overweight with at least one weight-related health condition like hypertension, Type 2 diabetes, or high cholesterol. "It is often used when lifestyle changes alone have failed to achieve the desired weight loss," says Dr. Samuel Green, a general practitioner.

Preparing for Injection: What You'll Need

Components of the Saxenda Pen

The Saxenda pen is a pre-filled, disposable injection pen that contains 18 mg of liraglutide. It is designed for ease of use and comes with clear markings to set the dosage. "The design of the Saxenda pen is tailored for patient-friendly use, aiming to make the process of self-injection as straightforward as possible," explains Dr. Michelle Collins, a pharmacologist.

Required Additional Supplies (Alcohol Wipes, Sterile Needle)

In addition to the Saxenda pen, you will also need alcohol wipes for sterilisation and a sterile, single-use needle for each injection. "It's crucial to use a new sterile needle for every injection to minimize the risk of infection," insists Dr. Laura Spencer, an infection control nurse.

Suitable Injection Sites for Saxenda


The abdomen is one of the most commonly used sites for subcutaneous injections, primarily because it is easier to pinch a layer of fat. "The abdomen is generally recommended as an injection site due to its ease of access," states Dr. Rebecca White, an experienced nurse in diabetes care.


The upper front and outer areas of the thigh are also suitable for subcutaneous injections. For those who might find the abdomen area sensitive or inconvenient, the thigh offers an alternative. "The thigh is generally less sensitive than other areas, making it a suitable alternative for those who experience discomfort in the abdomen," suggests Dr. Oliver Evans, a general practitioner.

Upper Arm

The back of the upper arm can also be used, though it might be less convenient for self-injection. "Patients who have difficulty injecting themselves may find the upper arm less accessible," notes Dr. Lisa Adams, a specialist in obesity management.

Guidelines on Rotating Injection Sites

Rotating injection sites is crucial to prevent the buildup of fatty tissue at the injection site, which can affect how the medication is absorbed. "It's advisable to rotate your injection sites to minimize skin irritation and maximize medication effectiveness," insists Dr. Hannah Roberts, a medical advisor for diabetes care.

Steps to Prepare the Injection Site

Cleaning the Area

Before administering the Saxenda injection, it is vital to ensure that the chosen injection site is clean to reduce the risk of infection. "I always recommend using alcohol wipes to sterilise the area thoroughly," advises Dr. Jessica Brown, a certified diabetes educator. Thoroughly swab the area in a circular motion, starting at the centre and working your way outward, to ensure comprehensive coverage.

Choosing the Exact Spot

When selecting the precise location for injection, remember to rotate your injection sites as advised. "To prevent issues like lipoatrophy or lipohypertrophy—where fatty tissue can either atrophy or build up—you should avoid injecting the same spot repeatedly," points out Dr. Timothy Johnson, an endocrinologist. Choose a site that's at least a finger's length away from the previous site.

Ensuring Proper Skin Tautness

The skin should be taut but not stretched, providing a smooth surface for injection. This can be achieved by pinching a small area of skin and fatty tissue between your thumb and forefinger. "A taut skin surface ensures that the needle will penetrate the subcutaneous layer effectively," says Dr. Maria Lewis, a clinical nurse specialist in diabetes care.

Assembling the Saxenda Pen

How to Attach the Needle

The Saxenda pen uses a screw-on needle tip, designed for single use. Remove the needle from its sterile packaging and screw it onto the tip of the Saxenda pen. "Make sure the needle is securely attached to avoid any leakage of medication," advises Dr. Patricia Wilson, a pharmacist.

Priming the Pen

Before the first use and whenever you attach a new needle, it’s essential to prime the pen to remove any air bubbles. To prime, dial a small dose (usually 0.01 mg) and press the injection button while pointing the needle upwards until a small drop appears at the tip. "Priming the pen ensures you get an accurate dose each time you inject," says Dr. Emily Foster, an endocrinologist.

Setting the Dose

Use the dose selector at the end of the Saxenda pen to dial your prescribed dose. The pen is calibrated to allow accurate dosage settings. "Always double-check the dose setting before injecting to avoid dosing errors," advises Dr. Alan White, a clinical pharmacologist.

Step by Step: Injecting Saxenda

Holding the Pen

Hold the Saxenda pen like a writing pen, using your thumb to push the injection button. The grip should be firm but comfortable. "A secure grip ensures better control during the injection," notes Dr. Lucy Thompson, an expert in medical device usability.

Inserting the Needle

Insert the needle into the pinched skin at an angle of about 45 to 90 degrees. "The angle of insertion is critical for ensuring the medication is administered into the subcutaneous tissue," explains Dr. Robert Clark, an expert in injection techniques.

Administering the Medication

Press the injection button fully while holding the pen steady. Count to 10 slowly to make sure the complete dose has been administered. "The slow count allows time for the medication to be fully injected and minimises leakage," states Dr. Karen Miller, a healthcare quality auditor.

Withdrawing the Needle

After administering the medication, withdraw the needle at the same angle you inserted it. Immediately dispose of the used needle in a designated sharps container to avoid injury or infection. "Safe disposal of the needle is a critical aspect of self-administration and healthcare at home," insists Dr. Vanessa Green, an expert in healthcare waste management.

Frequently Asked Questions

Can I inject Saxenda into muscle?

Injecting Saxenda into muscle is not recommended, as it is designed for subcutaneous (beneath the skin) injections. "Saxenda is formulated to be absorbed through the fatty tissue under the skin, and injecting it into a muscle could alter its absorption rate and effectiveness, potentially leading to complications", explains Dr. Emily Roberts, a pharmacologist.

What if the injection site becomes red or swollen?

Redness and swelling at the injection site can occur but should not be ignored. "While some irritation is normal, persistent redness or swelling could indicate an infection or allergic reaction," says Dr. Simon Fraser, an allergist. In such cases, it is advisable to seek medical attention immediately.

Can the same needle be used for multiple injections?

Reusing needles is strongly discouraged. "Using a needle more than once can introduce bacteria into the pen, increasing the risk of infection. Additionally, needles can become dull after a single use, making subsequent injections more painful," notes Dr. Rachel Green, an infection control nurse.

Expert Recommendations and Advice

Quotes from Medical Professionals

Dr. Philip Johnson, an endocrinologist, strongly recommends following the guidelines provided by your healthcare provider: "Adhering to prescribed procedures for Saxenda use maximises both safety and efficacy." Dr. Hannah Lewis, a general practitioner, also emphasises the role of regular consultations. "Regular check-ups allow your healthcare provider to monitor your progress and make necessary adjustments to your treatment plan."

Best Practices for Saxenda Injection

Adhering to best practices can make your Saxenda treatment more effective and less stressful. "Best practices include rotating injection sites to avoid lumps, storing the pen correctly to ensure it remains effective, and keeping an accurate record of your injections", states Dr. Kelly Nelson, a nursing professor, 

Safety Guidelines and Precautions

When to Seek Medical Help

If you experience severe or persistent side effects, it's imperative to consult a healthcare provider as soon as possible. "Any signs of allergic reaction, like hives or swelling of the face, lips, tongue, or throat, should be treated as a medical emergency," warns Dr. Edward Williams, an emergency room physician.

Signs of Incorrect Injection Technique

Incorrect injection technique can result in reduced efficacy of the medication and potentially cause complications. "Signs of incorrect technique include persistent pain at the injection site, frequent bruising, or a lump under the skin," says Dr. Laura Bennett, a certified diabetes educator. If you're encountering any of these issues, consult your healthcare provider for an assessment of your technique and any necessary adjustments.

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