Inderal improves blood flow and lowers blood pressure by relaxing blood vessels and slowing heart rate.
In order to treat:
elevated blood pressure
(Chest pain) angina
Avoiding heart attacks
Having a heart attack and surviving
Off-label uses of Inderal include treatment for anxiety, tremors, and stage fright.
The following are typical Inderal side effects:
Other negative effects of concern are:
Hypertension, or low blood pressure
Dyspnea, a shortness of breath
breathing issues such as wheezing or bronchospasm
(Bradycardia) A slow heartbeat
Call your doctor right away and stop taking Inderal if you experience any of these severe side effects.
Other drugs and this drug may interact. Tell your physician about all of the medications you are taking,
There are four oral tablet strengths of Inderal: 10 mg, 20 mg, 40 mg, and 60 mg. It can also be obtained as an injectable solution administered by a medical professional.
40 mg twice daily is typically the first dose for high blood pressure. Your doctor might increase your dosage to 80 mg twice daily if you tolerate the drug well.
The recommended starting dose for angina is 10–20 mg administered three–four times daily, preferably before painful activities.
The typical starting dose for migraines is 40 mg twice daily. Your doctor may increase your dose up to 320 mg per day if you still don't feel better after the first week.
Mechanism of Action
The heart's nerves contain beta-adrenergic receptors, which are blocked by inderal.This lessens heart rate, blood pressure, and heart effort by preventing norepinephrine and epinephrine from binding to these receptors.Inderal is thought to treat migraines by preventing serotonin, a neurotransmitter involved in pain signaling, from being active.
If you take any other medications, herbs, or vitamins, Inderal might interact with them. When a substance modifies how a drug functions, there is an interaction. This could be harmful or stop the medication from working properly.
Your doctor needs to carefully monitor all of your medications to help you avoid interactions. Tell your doctor about all prescription drugs, over-the-counter remedies, and dietary supplements you use.
If you take any of these medications, tell your doctor:
Combining Inderal with these medications can raise the amount of the drug in your body and increase the side effects.
Other beta blockers, calcium channel blockers, or heart medications may also interact with inderal.
Inderal is quickly absorbed from the digestive system and reaches its peak concentration in 30 to 60 minutes.Inderal has a half-life of 3-6 hours.The liver's cytochrome P450 enzymes, specifically CYP2D6, metabolize Inderal.It's possible for people who lack this enzyme to have decreased Inderal clearance and more side effects.