Elestat (eprstenant) is a synthetic version of the interferon protein. Your body uses interferon to combat viral infections.
Certain forms of pink eye (bacterial conjunctivitis) are treated with elestat.
Elestat can be used for additional conditions not covered in this medication guide.
Health Benefits
There are several potential health advantages of elestat, including:
prevention of viral infections
2. coping with pink eye
3. decreasing swelling
4. enhancing immune function
Side Effects
Elestat is typically tolerated well, but it can have some negative effects, including:
headache 1.
2. fatigue
3. muscular pains and aches
4. sickness and diarrhoea
Although serious side effects are uncommon, you should stop taking Elestat and get medical attention right away if you experience any of the following signs or symptoms:
1. Allergic reaction (face, lips, tongue, or throat swelling; breathing difficulty; hives)
2. tightness or chest pain
3. an unsteady heartbeat
Seizures 4.
5. Breathing difficulties
6. abrupt alterations in vision
Dosages
Elestat can be purchased as an eyedrop. Four times a day, one drop in each eye is the recommended dosage.
Ask your doctor if you can take Elestat every other day or reduce the dosage if you experience any bothersome side effects.
Interactions
Elestat might have interactions with other drugs, herbs, or dietary supplements. Therefore, before beginning Elestat, it's crucial to let your doctor know about any additional medications you're taking.
Elestat is probably safe for pregnant women in small doses during pregnancy and while nursing. Larger doses, though, might be harmful. It is best to completely avoid Elestat if you are breastfeeding.
Mechanism of Action
Elestat functions by acting similarly to interferon. Proteins of the type interferon aid in the defense against viral infections. Additionally, elestat has immune-stimulating and anti-inflammatory properties.
Elestat works to treat pink eye by eradicating the infection-causing bacteria.
Pharmacokinetics
When applied to the eye, elestat is quickly absorbed into the blood. It takes around two hours for it to reach its peak.
Elestat's half-life is unknown, but it is assumed to be comparable to other interferon proteins.
How long does it take for Elestat to work?
Elestat typically has effects within 24 hours. To see the full effects, though, could take up to two weeks.
Clinical Trials
There have been two clinical trials involving elestat. Elestat was successful in treating pink eye in one study. Elestat was able to shorten the duration of viral infections, according to the results of the other trial.
Elestat's safety and effectiveness are still being studied in depth.
How is it supplied?
Elestat comes in eyedrop form. Four times a day, one drop in each eye is the recommended dosage.
Ask your doctor if you can take Elestat every other day or reduce the dosage if you experience any bothersome side effects.
Symptoms of an Overdose
There haven't been any reports of Elestat overdoses. However, immediately seek medical attention if you experience any of the following symptoms after taking Elestat.
1. Allergic reaction (face, lips, tongue, or throat swelling; breathing difficulty; hives)
2. tightness or chest pain
3. an unsteady heartbeat
Seizures 4.
5. Breathing difficulties
6. abrupt alterations in vision
Chemical Structure
An artificial version of interferon alpha-2B is called elestat. It is 183 amino acids long and 21 kDa in molecular weight.
Alternatives to Elestat
Elestat has a lot of substitutes available. Other interferon proteins like interferon alfa-2a and alfa-2b are among them, as are antiviral medications like acyclovir and valacyclovir.
Is acyclovir more effective than Elestat?
Both Elestat and Acyclovir work well to treat viral infections. But since acyclovir is more effective and has a shorter half-life, it is more frequently used.
What’s the difference between Elestat and interferon alfa-2b?
The synthetic versions of interferon alpha-2B are elestat and interferon alfa-2b. Both their structure and their activities are similar. Elestat, however, has greater effectiveness than interferon alfa-2b.