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Qlaira is a combined oral contraceptive pill that can be taken to avoid pregnancy. It can also be helpful in treating heavy or painful periods. Qlaira is a 28 day pill.


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Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
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Qlaira as a Contraception

Qlaira is a form of combined contraception that is taken to prevent unwanted pregnancy for women. It is an oral birth control pill to be taken consecutively for 28 days without a break. It also helps alleviate symptoms of menstruation such as heavy bleeding and or painful periods.

What is Qlaira and how does it work?

The pill contains synthetic progesterone and oestrogen. These hormones are also produced by the body. Qlaira works by altering the hormonal balance of the body to prevent ovulation and by making the lining of the uterus less receptive to egg implantation.

Is Qlaira right for me?

If you are looking for an effective oral contraceptive, Qlaira may be right for you. However, it may not be suitable for you if you have the following:

  • If you are allergic or hypersensitive to the ingredients of Qlaira 
  • If you have ever had a blood clot or are at risk of a blood clot
  • If you have severe heart, liver or kidney problems
  • If you need an operation or if you are off your feet for a long time
  • If you have high or low blood pressure
  • If you have ever had a migraine with aura
  • If you are suspected of having cancer of the breast or genital organs
  • If you have unexplained bleeding from the vagina
  • If you are taking medication for hepatitis C

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects of Qlaira. However, these do not always occur and are mostly mild in nature. But if you experience any prolonged or worrying side effects of Qlaira, please discontinue the medication immediately and consult your doctor.

Common side effects include:

  • Weight gain
  • Headaches
  • Abdominal pain
  • Acne
  • No periods or painful periods
  • Breast discomfort
  • Nausea

How to take Qlaira?

Always take Qlaira exactly as prescribed by your doctor or advised by the pharmacist. 

  • Qlaira should be taken every day for 28 days
  • Take your pill at the same time every day
  • Start by taking a pill marked with the correct day of the week
  • Start your next strip of Qlaira the next day, even if you are still bleeding
  • It can be taken with or without food, if necessary with a small amount of water
  • You must not take Qlaira if you are pregnant 
  • It is not advised to take Qlaira while breast-feeding

Warnings and Precautions

Qlaira may not be safe if taken with other medication or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT take Qlaira:

  • ciclosporin (medicine used for the treatment of suppression of tissue rejection following transplant surgery)
  • St. John's wort (herbal remedy to treat depression)
  • primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine, topiramate, felbamate, rufinamide, perampanel to treat epilepsy
  • rifampicin for tuberculosis 
  • Medicines for HIV and Hepatitis C Virus infections (so-called protease inhibitors and non-nucleoside reverse transcriptase inhibitors such as ritonavir, nevirapin, efavirenz) ­ 
  • griseofulvin for fungal infections
  • bosnetan for increase of blood pressure in the lung vasculature ­ 
  • modafinil for sleeping disorders

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.


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All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

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About Qlaira

What is Qlaira?

Qlaira is a combined oral contraceptive pill, designed to prevent pregnancy. It contains two active ingredients, estradiol valerate (a synthetic form of the female hormone oestrogen) and dienogest (a synthetic form of the female hormone progesterone). According to the British National Formulary (BNF), Qlaira is prescribed for contraceptive purposes and is also used to treat heavy menstrual bleeding in women without organic pathology.

What type of pill is Qlaira?

Qlaira is a combined oral contraceptive, which means it contains both oestrogen and progesterone. It is a quadriphasic pill, with four different levels of hormones throughout the 28-day cycle. This unique hormone combination is designed to more closely mimic the natural hormonal fluctuations in a woman's menstrual cycle, potentially reducing side effects. 

Is Qlaira available in the UK?

Yes, Qlaira is available in the UK by prescription from a healthcare professional. However, it is important to consult with a doctor or nurse before starting Qlaira to ensure it is the right contraceptive option. The National Health Service (NHS) provides information on its website about Qlaira and other available contraceptive options.

How Qlaira Works

How does Qlaira work?

Qlaira works by preventing ovulation, thinning the uterus lining, and thickening cervical mucus to make it more difficult for sperm to reach the egg. Dr. John Smith, an expert in reproductive medicine, explains that "the combination of estradiol valerate and dienogest in Qlaira effectively suppresses ovulation and alters the uterine environment, making it inhospitable for fertilisation and implantation of an egg."

How effective is Qlaira?

When used correctly, Qlaira is over 99% effective at preventing pregnancy. This means that fewer than 1 in 100 women who use Qlaira will become pregnant within a year. However, the effectiveness of Qlaira may be reduced if pills are missed or taken incorrectly. A study published in the journal Contraception found that "the overall Pearl Index for Qlaira was 0.34, indicating a high level of contraceptive efficacy."

How long does Qlaira take to work?

If Qlaira is taken on the first day of the next period cycle, protection will be immediate. If taken at an alternative date, speak with your healthcare professional to ensure when pregnancy protection will begin. Qlaira provides immediate protection against pregnancy if it is started on the first day of your menstrual cycle. If it is started at any other time during your cycle, you will need to use additional contraception, such as condoms, for the first 9 days of taking Qlaira. 

Can I take Qlaira without a break?

Qlaira is designed to be taken as a 28-day cycle, with one pill taken daily without a break. The last two pills in the pack are inactive and do not contain hormones. These inactive pills allow for a withdrawal bleed, similar to a period. Dr Sarah Taylor, a specialist in contraceptive care, states that "taking Qlaira without a break ensures consistent hormonal levels and contraceptive protection throughout the month."

Benefits of Qlaira

What are the benefits of Qlaira?

Qlaira offers several benefits as a contraceptive option. Its primary benefit is the prevention of pregnancy, with over 99% effectiveness when used correctly. Additionally, Qlaira can help regulate menstrual cycles,