A prescription drug called disalcid is used to treat gout and stop reoccurring gout attacks. Disalcid is a member of the xanthine oxidase inhibitor drug class.
The mechanism by which Disalcid reduces the likelihood of gout attacks is unknown.
Health Benefits
Disalcid has been demonstrated in clinical studies to:
- Reduce the frequency of gout flare-ups
- Reduce gouty joint pain
- Lower blood uric acid levels.
Side Effects
Disalcid's typical side effects include:
- Diarrhea
- Diarrhea
- Vomiting
- Stomach ache
– Rash
- Migraine
Among the less frequent side effects are:
– Distorted vision
- Taste changes
- Otolaryngitis
Disalcid should not be taken again if you experience any of these severe side effects. Instead, call your doctor right away.
Dosages
Disalcid comes in the following strengths as tablets:
– 500 mg
– 750 mg
Disalcid's starting dose for treating gout is either 3000 mg once daily or 750 mg taken orally four times daily. Depending on how you react to the medication, your doctor may change the dose.
To reduce your risk of experiencing stomach upset, take Disalcid with food or milk.
Take the tablet whole; do not chew, break, or crush it.
Take Disalcid as soon as you remember if you miss a dose. Skip the missed dose and carry on with your regular dosing schedule if it is almost time for your next dose.
Interactions
Disalcid and other drugs may interact. Give your doctor a complete list of all the drugs and supplements you take. If the potential benefit does not outweigh the potential risk to the fetus, disalcid should not be used during pregnancy. It is unclear whether this medication enters breast milk. Before breastfeeding, speak with your doctor.
Medication interactions with Disalcid include, for instance:
- Allopurine
– Azathioprine
- Closporine
– Mercaptopurine
– Theophylline
Drug Warfarin
– Zidovudine
The list of medication interactions for Disalcid is not exhaustive. For more information, consult your physician or pharmacist.
Mechanism of Action
Disalcid's precise mode of operation is unknown. It is believed to function by preventing the production of uric acid by xanthine oxidase. Disalcid may lessen the risk of gout attacks by lowering uric acid levels.
Pharmacokinetics
Disalcid is quickly and completely absorbed after being administered orally.
Disalcid is widely dispersed throughout the body, according to distribution.
Disalcid is metabolized in the liver through oxidation and conjugation, leading to its elimination. The urine is where the metabolites are eliminated. The half-life of disalcid is 1-2 hours.
Alternatives to Disalcid
Disalcid is not the only medication available to treat gout. A few of these are:
- Allopurine
Drug Colchicine
– Indomethacin
- Nappren
- Benemid
These are merely a few illustrations. Gout can be treated with a variety of other drugs, both prescription and over-the-counter. Before choosing a course of treatment, discuss all of your options with your doctor.
Clinical Trials
Disalcid was shown to be effective in reducing the frequency of gout flare-ups and improving gout symptoms in a 12-week, randomized, double-blind, placebo-controlled trial involving 496 gout patients.
Another 12-week, double-blind, randomized trial with 582 gout patients found that Disalcid was superior to placebo in lowering blood uric acid levels and preventing recurrent gout attacks.
Numerous other clinical studies have examined the effectiveness of Disalcid in the treatment of gout. Disalcid has generally been shown in these studies to be secure and efficient in the short-term management of gout.
Is Naproxen more effective than Disalcid?
This question lacks a definite response. It has been demonstrated that both drugs work well in the treatment of gout. While other studies did not find a difference in the two medications' efficacy, some studies have shown Naproxen to be more effective than Disalcid. Consult your doctor about the best medication for you.