Spironolactone and hydrochlorothiazide are two medications that together make up the drug aldactazide. Edema and high blood pressure are both treated with it.

How does Aldactazide work?

Aldactazide functions by assisting the body in eliminating extra salt and water. By raising urine production and lowering the body's salt absorption, it accomplishes this.

What are the benefits of Aldactazide?

Blood pressure can be lowered and fluid retention can be lessened with aldactazide. Shortness of breath and swelling in the legs and feet can both be helped by this.

What are the risks of Aldactazide?

Dizziness, headaches, and diarrhea are a few of the side effects that aldactazide can produce. Additionally, it may result in excessively high blood potassium levels. For those who have heart or kidney issues, this could be dangerous.

Aldactazide is a drug that requires a prescription. Both a tablet and an oral solution are available. A generic version of aldactazide is not accessible.

Dosages of Aldactazide:

25 mg/15 mg and 50 mg/25 mg tablets

-10 mg/5 mg per 5 mL for the oral solution.

Aldactazide's benefits include:

-25 mg/15 mg

-50 mg/25 mg

Various Aldactazide formulations:

-Oral remedy


Aldactazide is a drug that requires a prescription. Both a tablet and an oral solution are available. A generic version of aldactazide is not accessible.

Pharmacokinetics of Aldactazide:

-75% bioavailability

Protein binding: 94–98%

Hepatic metabolism (CYP3A4)

-Lifetime of 1.4 hours

The oral solution and tablet forms of aldactazide are bioequivalent. They are therefore equally absorbed into the body, according to this.

Aldactazide is a drug that requires a prescription. Both a tablet and an oral solution are available. A generic version of aldactazide is not accessible.

Aldactazide Warnings:

A black box warning is present on aldactazide due to its potential for serious side effects. Low blood potassium levels and high blood calcium levels are two of these side effects. Birth defects can also result from aldactazide use.

When used during pregnancy, aldactazide should not be taken unless the advantages outweigh the risks. Aldactazide should be stopped immediately if you become pregnant while taking it, and you should contact your doctor right away.

Aldactazide may be harmful to a nursing baby if it enters breast milk. Aldactazide should not be taken while nursing a baby.

Aldactazide Interactions:

If you take any other medications, vitamins, or herbs, aldactazide may interact with them.When a substance modifies how a drug functions, there is an interaction.This could be harmful or stop the medication from working properly.Your doctor needs to carefully monitor all of your medications to help you avoid interactions.Tell your doctor about all of the drugs, vitamins, and herbal remedies you are taking.Speak with your doctor or pharmacist to learn how this medication may interact with other medications you are taking.The following is a list of medications that may interact with aldactazide.-Diuretics-Diuretics that conserve potassium-Adequate potassium intakeInhibitors of ACE-ARBs, or angiotensin II receptor blockersNSAIDs (non-steroidal anti-inflammatory drugs).

Ask your doctor or pharmacist if you have concerns about possible drug interactions that could affect you.

Aldactazide and Alcohol:

Alcohol consumption should be avoided while taking Aldactazide. You run a higher risk of having low blood potassium levels if you drink alcohol.

Overdosages of Aldactazide

Aldactazide overdoses can be harmful.

Among the signs of an overdose are the following:




-More frequent urination

-Slow heart rate

- Weak muscles

Mechanism of Action of Aldactazide

A diuretic, aldactazide. It functions by increasing the amount of salt and water the body excretes. Blood pressure is lowered and fluid retention is decreased as a result.

How to Take Aldactazide:

-Aldactazide should be taken exactly as directed by your physician.

Usually, aldactazide is taken once or twice per day.

Aldactazide may be taken with or without food.

-Before each use, thoroughly shake the oral suspension.

-Use an oral syringe, medicine cup, or measuring spoon that is clearly marked to measure the oral suspension.

If you have trouble swallowing the tablet whole, you can crush it and mix it with water.

-Unless your doctor instructs you otherwise, drink plenty of fluids to prevent dehydration.

Aldactazide is typically taken for no longer than four weeks. Throughout treatment, it will be necessary to frequently check your blood pressure. If your blood pressure does not continue to drop, you might need to take Aldactazide for a longer period of time.

Aldactazide withdrawal may cause an increase in blood pressure.