The medication imitrex is used to treat migraines, aura or not. An aura is an odd sensation or visual commotion that alerts you to an impending attack. It is not employed to stop migraines. There are additional uses for imitrex besides those covered in this medication guide. This article is written to provide information to Welzo users so they can better understand Imitrex.


Imitrex is quickly absorbed and reaches its peak concentration in about an hour. Sumatriptan administered subcutaneously has a bioavailability of about 12%. After receiving a 100 mg oral dose or a 25 mg subcutaneous dose, the peak plasma concentrations are around 2 ng/mL. Sumatriptan is primarily excreted in the urine as an unchanged drug when it is administered subcutaneously. It has an elimination half-life of two to three hours. Neither cytochrome P450 enzymes nor monoamine oxidase extensively metabolize sumatriptan.

Warnings for imitrex

If you have a sumatriptan allergy, circulation issues, heart disease, angina (chest pain), blood pressure issues, a history of heart attack or stroke, severe liver disease, uncontrolled hypertension (high blood pressure), or a headache that resembles your migraine headaches, you should not take this medication.

When taking Imitrex, avoid taking any other migraine medication, such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig), within 24 hours of taking that medication. Imitrex should not be taken while you are pregnant. The unborn child could suffer harm. While you are taking this medication and for at least two weeks after your last dose, use birth control to avoid getting pregnant. Assumatriptan can enter breast milk, endangering a nursing infant. If you use this medication, you shouldn't breastfeed. Tell your doctor if you have ever experienced any of the following: heart disease, a heart attack, a stroke, blood pressure issues, liver or kidney disease, seizures or epilepsy, depression, anxiety, or other mental health issues; xanthoma (skin yellowing). Without consulting a doctor, never administer this medication to anyone who is younger than 18.

Side Effects

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives; trouble breathing; swelling of your face, lips, tongue, or throat. Call your doctor right away if you experience any of the following symptoms: severe stomach pain that comes on suddenly, bloody or watery diarrhea, fast or pounding heartbeats, tremor (uncontrollable shaking), shortness of breath, feeling faint, headache with chest pain, severe dizziness, fast or pounding heartbeats, jaundice (yellowing of the skin or eyes), seizure (convulsions), problems with vision or speech. Warmth, redness, or a tingling sensation under your skin, pressure or a heavy feeling, chest pain, a rapid heartbeat, headache, dizziness, drowsiness, weakness, nausea, and vomiting are all possible side effects of imitrex.

Dosage and Administration

Imitrex is available in tablet, water-soluble powder, and nasal spray forms. The dosage for the treatment of migraines is 25 mg, 50 mg, or 100 mg. The nasal spray and tablets can be used to prevent migraines as well as treat acute migraine attacks. 6 mg of the powder per kilogram (kg) of body weight, up to a maximum of 200 mg, is the recommended dosage. You can take Imitrex with or without food. Spray the nasal spray into the air away from your face to create a fine mist before using it.

The first dose for headaches is typically taken as soon as you become aware of the headache. Take a second dose two hours after the first if your headache doesn't go away entirely or goes away and returns. Never exceed 200 mg in a 24-hour period. Call your doctor if, despite taking 200 mg in total throughout the day, you continue to experience migraine symptoms.

The dosage range for migraine prevention is 50 mg to 100 mg once daily.


Call your neighborhood poison control center or emergency room right away if you take too much sumatriptan. Sumatriptan overdose can be fatal.


Away from light and moisture, keep items at room temperature. Keep it out of the bathroom. Keep children and pets away from all medications.

Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. When the product is no longer needed or has expired, dispose of it properly. For more information on how to properly dispose of your product, speak with your pharmacist or the local waste management company.