Trileptal
Health Benefits
It has been demonstrated that trileptal works well to lessen seizures in epileptics.
Trileptal was effective in reducing seizure frequency in children and adolescents with newly diagnosed partial epilepsy, according to a single-dose, double-blind, placebo-controlled trial.
In a different study, it was discovered that Trileptal is just as effective at treating partial seizures as carbamazepine (Tegretol).
Additionally, trileptal has demonstrated efficacy in the management of bipolar disorder.
In a 12-week, randomized, double-blind, placebo-controlled trial, it was discovered that Trileptal significantly outperformed the placebo in easing mania symptoms in bipolar patients.
Side Effects
Trileptal's most typical side effects include:
headache, dizziness, drowsiness, blurred vision, tremor, skin rash, nausea, vomiting, diarrhea, and constipation.
Trileptal side effects that are less frequent include:
Depression, anxiety, restlessness (insomnia), adjustments in body weight, decreased appetite, hair loss, and alterations in menstrual cycle.
Serious allergic reactions (anaphylaxis), angioedema (under-the-skin swelling), Stevens-Johnson syndrome (a potentially fatal skin reaction), and aseptic meningitis (inflammation of the brain's lining) are just a few of the uncommon side effects of Trileptal.
Call your doctor right away if you experience any of the following side effects:
hives, rash, itching, breathing or swallowing issues, as well as swelling of the face, lips, tongue, or throat.
If you have ever experienced a severe allergic reaction to carbamazepine or oxcarbazepine, you should avoid taking Trileptal.
Dosage
Adults with partial seizures should begin taking Trileptal at a dose of 300 mg twice daily.
For children with partial seizures aged 2 to 16 years, a starting dose of 10 mg/kg/day divided into two doses is advised.
60 mg/kg/day is the maximum dose that is advised for children between the ages of 2 and 16.
Adults with generalized tonic-clonic seizures should begin taking Trileptal at a dose of 600 mg once daily.
For adults with generalized tonic-clonic seizures, the maximum daily dose of trileptal is 1,200 mg.
Interactions
Trileptal may interact with other antiepileptic drugs, antibiotics, blood thinners, birth control pills, cancer chemotherapy drugs, heart or blood pressure drugs, or HIV/AIDS drugs.
Inform your doctor about all prescription, over-the-counter, and dietary supplements you are taking.
Never begin a new medication without first consulting your physician.
The following are some examples of drugs and Trileptal that may interact:
birth control pills, blood thinners like warfarin (Coumadin), cancer chemotherapy drugs, heart or blood pressure medications like diltiazem (Cardizem, Dilacor XR, Tiazac) or verapamil (Calan, Covera HS, Isoptin SR, Verelan), HIV/AIDS drugs like atazanavir (Reyataz) or ritonavir (Norvir), antibiotics like clarithromycin
Grapefruit juice may also interact with trileptal.
How does it work?
Trileptal is a member of the anticonvulsant drug subclass. It reduces the seizure-inducing nerve impulses in the body.
Pharmacokinetics
When taken orally, trileptal is quickly and completely absorbed. It crosses the blood-brain barrier and is widely dispersed throughout the body.
Trileptal has a half-life of 10 to 16 hours.