Treatment options

  • Next day delivery
  • Discreet & confidential
  • UK licensed medication
Epiduo Gel - welzo
Epiduo Gel - welzo
Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."

Epiduo Gel

Epiduo Gel - welzo
Epiduo Gel - welzo
Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
20 Reviews
Sale price £29.99
In stock.
20 Reviews

Epiduo Gel is a prescription topical medication that can be used to treat adult acne. The active...

Epiduo Gel is a prescription topical medication that can be used to treat adult acne. The active ingredients, adapalene and benzoyl peroxide, work to control moderate to severe acne by removing the dead skin cells and killing the bacteria living on the skin. 

Free delivery by Tomorrow, April 27.
Order within
2.5% Benzoyl Peroxide 0.1% Adapalene
1 tube (45g) £29.99
2 tube x (45g) £58.99
Pricing is provided as a reference. Treatment will be shown after completing the consultation. The final decision on issuing this medication remains with the prescriber.
Email when stocked
Secure Transaction
In stock.
As seen in
The_Daily_Mirror_logo - welzo
yahoo_01d90440-d295-40e7-9266-347e0db579ff - welzo
metro_1 - welzo
100% UK-based pharmacies
Our team of doctors, network of pharmacy suppliers and our support staff, are all UK-based.
Free advice and support
Have a question? Email support is always free; Monday - Friday, 9am - 5pm.
Free UK delivery over £40
Fast, securely delivered, tracked next-day United Kingdom delivery from £3.99. Or free when over £40.
We’re rated 4.9 out of 5
Based on over 24,000+ reviews on Trustindex, Trustpilot and Google.
Nathalie Hayek reviewed
"Customer service was quick to respond and medication arrived the very next day!"
Anthony Limasol reviewed
"Quick, fast and reliable service. Use Welzo monthly for my medication."
Remeece Freeman reviewed
"No fuss, and fast delivery. Welzo dispatched my order the same day and it arrived in the morning."
As seen in
The_Daily_Mirror_logo - welzo
yahoo_01d90440-d295-40e7-9266-347e0db579ff - welzo
metro_1 - welzo


What is Epiduo Gel?

Epiduo Gel is a topical treatment for the skin condition of Acne vulgaris. It is suitable for adults, adolescents and children aged 12 and over. 

How does it work?

The gel contains two active ingredients: adapalene 0.1% and benzoyl peroxide 2.5% which work to reduce the growth of the keratin surface skin cells that are responsible for blocking pores and causing acne. They also are used to kill the bacteria and increase cell turnover for clearer skin. 

Is Epiduo Gel suitable for me?

Epiduo Gel can be used on the face and in other areas where there have been acne flare-ups. If you wish to reduce the redness, swelling and overall appearance of acne, ask your doctor about Epiduo Gel. 

However, Epiduo may not be suitable if the following applies:

  • If you are pregnant or planning to become pregnant
  • If you are allergic to Adapalene or any of its ingredients

The product images shown may represent the range of products, or be for illustration purposes only and may not be an exact representation of the product.

Dosage of Epiduo

Commonly Used Dosage Guidelines for Epiduo Gel.

Apply to clean and dry skin. Apply thinly at bedtime to affected areas. Wash hands after use. 

  • DO NOT use Epiduo on areas where you have cuts or scrapes or if you have a skin condition called eczema.
  • Avoid contact with the eyes, mouth, or nostrils, and avoid other very sensitive areas of the body. If accidental contact does occur, immediately wash with warm water.
  • Avoid exposure to sunlight and artificial UV light whilst using Epiduo

Disclaimer: This website does not provide medical advice. No information listed on this website is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undergoing a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Warning and Precautions of Epiduo Gel

Epiduo Gel may not be safe if used with certain medications or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT use Epiduo Gel:

  • If using other products containing retinoids and / or benzoyl peroxide. Discontinue the use of these products while using Epiduo Gel.
  • If you are using cosmetic that may dry or exfoliate the skin, avoid using these product while using Epiduo Gel.

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.

Epiduo Gel Reviews

Epiduo Gel is an effective treatment, but it might not work for all patients. Find out a comprehensive list of reviews on Epiduo Gel below taken from independent sources.

Read review on Epiduo Gel below:

  • Epiduo Gel has a rating of 7.3 out of 10 for acne treatment according to user reviews on
  • Patients who have used have rated us “excellent” on Trustpilot. We have over 20,000+ reviews from multiple platforms, click here to view our Trustpilot reviews and click here to read our reviews on Trustindex.

How to use Epiduo?

Always use Epiduo exactly as prescribed by your doctor or advised by the pharmacist. 

Epiduo use is not recommended for children under 9 years of age. 

  • Wash and dry your skin thoroughly and apply a thin layer of Epiduo on the affected area.
  • After using Epiduo, wash your hands properly. Avoid getting the gel around or in the eyes, mouth and nose. 
  • Apply Epiduo once a day before bed, or as instructed by your provider.
  • Using the gel for the duration your doctor has advised.
  • Consult with your provider if irritation is persistent. 

Side Effects of Epiduo Gel

All medications can cause potential side effects, below we have listed some potential side effects, however, these do not always occur.

  • Dry skin
  • Irritant contact dermatitis
  • Skin irritation and burning

Disclaimer: This website does not constitute as medical advice, you should also consult with a doctor before taking medication. If you experience any major reactions to any medication you taking, you must seek immediate medical attention.

Epiduo Gel (Benzoyl Peroxide 2.5% Adapalene 0.1%) Patient Leaflet


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!

Product reviews

Complete a Quick & Free Online Consultation

This is a quick process and should only take 1 - 2 minutes. All of your answers are confidential, and just like a GP consultation, you will know what treatment is most suitable for you instantly upon completion.

Place Your Order for Epiduo Gel and Upload ID

Once you have completed the quick online form, select the treatment option most suitable to you and checkout securely. If you are eligible for treatment you will be asked to upload an ID and whole body picture.

Free Guaranteed Delivery

A medical professional will review your answers to the online medical consultation and determine if it’s safe to prescribe and what treatments are available.

Epiduo Gel Acne Treatment

What is Epiduo Gel?

Epiduo Gel is a topical medication used for the treatment of acne vulgaris. It contains two active ingredients: adapalene (a type of retinoid) and benzoyl peroxide, which work together to reduce inflammation and kill bacteria.

What is Epiduo Gel Used For?

Epiduo Gel is used to treat acne vulgaris in individuals aged 9 and above. It helps reduce the number of acne lesions, both inflammatory and non-inflammatory.

How does Epiduo Gel Work?

Epiduo works by combining the actions of its two active ingredients. Adapalene, a retinoid, works primarily by unclogging blocked pores, while benzoyl peroxide has an antibacterial effect and helps to reduce inflammation.

Epiduo Dosage & Usage

How do I use Epiduo?

Epiduo must be applied to the entire acne-affected areas once a day, usually in the evening, on clean and dry skin. Avoid contact with the eyes, lips and nostrils.

Do I have to use Epiduo at night?

Yes, it is typically recommended to apply Epiduo at night, as retinoids might be degraded by sunlight.

How long should I use Epiduo for?

The length of treatment with Epiduo varies depending on the severity of the acne, but many people see improvements within 1-4 weeks. However, it's recommended to use it continuously for the duration advised by a healthcare provider.

Epiduo Side Effects & Considerations

What not to do when using Epiduo?

While using Epiduo, avoid exposure to strong sunlight and sunbeds, as it potentially makes the skin more sensitive to UV light. Avoid using other acne products that cause irritation, like medicated or abrasive soaps and cleansers, or cosmetics that have a strong drying effect.

Epiduo Gel Side Effects

Side effects of Epiduo Gel include skin irritation, dryness, and redness, particularly at the start of treatment. These side effects usually decrease with continued use. If experiencing severe or prolonged irritation, consult with a healthcare provider.

What happens when you stop using Epiduo?

If one stops using Epiduo, the acne might return. It's important to continue using it for the duration advised by a healthcare provider.

Epiduo Availability & Pricing

Can You Buy Epiduo Gel Over the Counter?

No, Epiduo is a prescription-only medication.

Epiduo Price

The price of Epiduo varies depending on the location and the pharmacy. Epiduo is priced at £24 on Welzo.

Epiduo Alternatives

Alternatives to Epiduo Gel

If Epiduo is not suitable or not effective, other acne treatments are available, including other topical treatments (like tretinoin or azelaic acid), oral antibiotics, hormonal treatments, or isotretin retinoin for severe cases. The best alternative depends on the individual circumstances and must be discussed with a healthcare provider.

Epiduo vs Differin

While both Epiduo and Differin contain the retinoid adapalene, Epiduo contains benzoyl peroxide as well. Epiduo targets acne in more ways – by unclogging pores and reducing inflammation and bacteria.

Epiduo vs Duac

Epiduo and Duac are both topical acne treatments, but they contain different active ingredients. Duac contains clindamycin (an antibiotic) and benzoyl peroxide. The choice between the two usually depends on the individual's skin type and acne severity.


How effective is Epiduo?

Epiduo has been shown to be effective in treating acne vulgaris in numerous studies. Many people see a significant improvement in their acne after 1-4 weeks of use. However, the effectiveness varies from person to person.

Epiduo isn't working - what now?

If an individual has been using Epiduo consistently and is still not seeing improvements after 4 to 8 weeks, or if the acne gets worse, consult a healthcare provider. They are able to suggest a different treatment or approach.

Can I wear makeup with Epiduo?

Yes, a person is able to wear makeup while using Epiduo. However, it's important to use non-comedogenic (won't clog pores) makeup and to cleanse the skin thoroughly before applying Epiduo in the evening.

Is Epiduo the same as retinol?

No, while Epiduo contains a type of retinoid known as adapalene it is not exactly the same. While both retinol and adapalene are vitamin A derivatives and have similar effects on the skin, adapalene is more potent and is typically used for the treatment of acne.

Epiduo Purging

During the initial stages of treatment with Epiduo, one might notice a flare-up of acne. This is sometimes referred to as "purging" and is due to the action of the medication on the pimples forming within the skin. This is usually temporary and improves with continued use.

Buy Epiduo Gel Online

Please note the information below is intended for general knowledge, please read the patient information leaflet and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

You can buy Epiduo Gel online from our UK-registered online pharmacy partners. Complete an online consultation form and our system will show you if you are eligible to purchase Epiduo Gel online. Our pharmacists will then review your order of Epiduo Gel and dispatch it discreetly to your address.

How to buy Epiduo Gel online?

You can buy Epiduo Gel by following the following steps.

  1. Fill out our online consultation form
  2. If you are eligible to purchase Epiduo Gel you will be shown it as one of your treatment options
  3. Pay online and receive your order to the comfort of your chosen address

Can I get Epiduo Gel on the NHS?

Whether or not you can get Epiduo Gel on the NHS is dependent on your local guidelines and eligibility status. It is best to contact your local GP service if you are unsure of whether you can get Epiduo Gel from the NHS.

Can you get Epiduo Gel over the counter?

No, you can’t get Epiduo Gel over the counter without a prescription or consultation. Epiduo Gel is a regulated medication so all purchases need to have a prescription and/or suitable consultation form completed.

Can I buy Epiduo Gel online even if I have never taken it before?

A prescribing pharmacist will need to review your consultation form before the medication can be dispatched. One of our partner prescribing pharmacists will review the consultation form and will decide if you are eligible to buy Epiduo Gel.

Is Epiduo Gel safe?

If you have been prescribed Epiduo Gel then it is at the discretion of the prescriber.

However, all medications can potentially have adverse effects and should be taken exactly as prescribed. If you experience any side effects when taking Epiduo Gel then you should contact a doctor immediately.

Are there any foods that should be avoided when taking Epiduo Gel?

We recommend you read the patient information leaflet for this product thoroughly before taking the treatment. This is essential to understanding any interactions that can occur and to take the medication safely.

Can I buy Epiduo Gel from Boots?

It is generally possible to purchase medication, including Epiduo Gel, from UK pharmacies like Boots. However, I recommend checking the Boots website or contacting Boots directly for the most current and accurate information. Remember to consult with a healthcare professional before starting any new medication.

Can I buy Epiduo Gel from Superdrug?

If you would like to buy Epiduo Gel, you will need to check availability on the Superdrug website.

Can I buy Epiduo Gel from Amazon?

Amazon does not sell medication such as Epiduo Gel, as they are not a pharmacy service provider. Always check with Amazon to see what they sell.

How long does Epiduo Gel take to work?

The time it takes for a Epiduo Gel to work can vary greatly depending on several factors, such as the strength, the individual's age, weight, and overall health, as well as any potential interactions with other medications or substances. Generally, the effects of Epiduo Gel may be noticeable within the time frame outlined by the prescribing pharmacist. It is important to follow the prescribed dosage and instructions provided by your healthcare professional, and to consult them if you have any concerns or questions about the medication's efficacy or possible side effects.

How effective is Epiduo Gel?

The effectiveness of Epiduo Gel can vary significantly depending on various factors, such as the dosage, the condition being treated, the individual's age, weight, and overall health, as well as the presence of any other medications or substances that might interact with it. While some medications may be highly effective for certain individuals and conditions, others might experience a lesser degree of benefit or may require adjustments to the dosage or additional treatments to achieve the desired results.

What are the risks of taking Epiduo Gel?

At Welzo, we are dedicated to providing our customers with accurate and comprehensive information about medications. We believe that understanding the potential risks and side effects associated with a medication is essential for making informed decisions about your health. This guide outlines some general considerations for assessing the risks of medication and includes references to the National Health Service (NHS) for further information.

  1. Read the Patient Information Leaflet (PIL): Every medication comes with a Patient Information Leaflet, which provides essential details about the drug, its uses, and potential side effects. Be sure to read this leaflet carefully before starting any new medication. The Electronic medicines compendium has a list of patient leaflets. you can visit by heading to
  2. Be aware of potential side effects: All medications have the potential to cause side effects, ranging from mild and short-lived symptoms to more serious, long-lasting issues. It's important to understand the possible side effects of a medication and how to manage them. The NHS has a helpful resource on managing medication side effects, while also speaking to a healthcare professional is important in understanding any potential risks of taking Epiduo Gel.
  3. Interactions with other medications: Some medications may interact with others, leading to increased side effects or reduced effectiveness. Make sure to inform your healthcare professional about all the medications and supplements you are currently taking. The NHS offers a useful tool for checking potential drug interactions here.
  4. Contraindications and precautions: Certain medical conditions or factors may make it unsafe for you to take a particular medication. Before starting any new medication, inform your healthcare professional about your medical history and any current health issues. The NHS provides more information about contraindications and precautions here.
  5. Appropriate use and dosage: It's crucial to follow the prescribed dosage and instructions for taking a medication to ensure its effectiveness and minimise the risk of side effects. The NHS has a useful guide on using medicines safely here.
  6. Monitoring and follow-up: Some medications require regular monitoring or follow-up appointments with your healthcare professional to ensure their safety and effectiveness. Be sure to schedule and attend these appointments as needed.

Can I buy Epiduo Gel in the UK?

Yes, you can buy Epiduo Gel in the UK with a valid prescription and or consultation form. Epiduo Gel is available in the UK for purchase from local pharmacies with a valid prescription and or consultation and to purchase from Welzo if in stock. It is imperative that you ensure that the pharmacy you are buying the products from is licensed and registered with the General Pharmaceutical Council (GPhC).

Where can I buy Epiduo Gel?

You can buy Epiduo Gel online from upon completion of a consultation form and a free review from a prescribing pharmacist.

Are Epiduo Gel users satisfied with the product?

We have a list of reviews from customers taking Epiduo Gel at the bottom of this page. For more information of the reviews of Epiduo Gel head over to for further details.

Can I buy Epiduo Gel from an online pharmacy?

Yes, you can purchase Epiduo Gel from an online pharmacy. However, this is dependent on your eligibility for the medication.

How much does Epiduo Gel cost?

The costs of Epiduo Gel are listed at the top of the page. Pricing is provided as a reference as treatment options will be shown upon completing the consultation form.