Sirdupla Information Disclaimer

Please note that we do not distribute or sell Sirdupla. The content provided on this webpage is intended solely for informational and educational purposes. It should not be construed as medical advice, diagnosis, or treatment recommendation. Always consult a qualified healthcare professional for personalised medical advice and treatment options.

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Sirdupla - welzo
Sirdupla - welzo


Sirdupla - welzo
Sirdupla - welzo
Sale price £51.00
In stock.

Sirdupla is an asthma medication that works to keep airways in the lungs open while reducing any...

Sirdupla is an asthma medication that works to keep airways in the lungs open while reducing any irritation or swelling. This is a preventative asthma medication that can provide relief for up to 12 hours.

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In stock.


Sirdupla for Asthma & Breathing Problems

Asthma is a condition that primarily affects the lungs and can cause a range of breathing difficulties. Asthma often occurs after exposure to a trigger, however, it can happen randomly. Triggers may include common allergies to pollen or animal dander, infections, environmental changes or from exercise.

Sirdupla is a prescription medicine used for the treatment of breathing problems such as asthma. Sirdupla can help to stop symptoms such as breathlessness and wheezing; however, it should not be used to relieve these sudden attacks. This medicine is intended for use by adults aged 18 years and over. There are several underlying medical conditions and medications that should not be taken with this medicine. Consult with your doctor before use.

What is Sirdupla and how does it work?

Sirdupla contains two active substances that can provide long-lasting effects. Salmeterol, which is a long-acting bronchodilator and fluticasone propionate which is a glucocorticosteroid that can reduce swelling and irritation in the lungs.

This is not a reliever inhaler and should not be used to stop sudden attacks of breathlessness or wheezing.

Is Sirdupla right for me?

If you are diagnosed with asthma, COPD or other breathing condition, you may be prescribed a Sirdupla by a doctor or healthcare professional. However, it may not be suitable for you if you have the following:

  • If you are allergic to salmeterol and fluticasone propionate or any other ingredients in this medicine
  • If you have diabetes mellitus
  • If you have a history of heart problems
  • If you have an overactive thyroid gland
  • Low potassium in your blood
  • Tuberculosis now or in the past, or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), corticosteroids, medicines to treat infections, beta-blockers or other bronchodilators
  • If you are under the age of 18

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects of the Sirdupla. However, these do not always occur and are mostly mild in nature. But if you experience any prolonged or worrying side effects of the Sirdupla, please discontinue the medication immediately and consult your doctor.

Common side effects include:

  • Headache
  • An increased number of colds, reported in patients with COPD
  • Thrush in the mouth and throat
  • Aching, swollen joints and muscle pain.
  • Muscle cramps.

How to use a Sirdupla?

Always use Sirdupla exactly as prescribed by your doctor or advised by the pharmacist. The recommended starting dose for adults is two puffs (25/125) a day to relieve asthma, however, in presence of other factors, this may be increased or decreased accordingly as per the prescriber's clinical judgement. 

For adults:

  • Sirdupla 25/125 - 2 puffs twice a day
  • Sirdupla 25/250 - 2 puffs twice a day


  • Start to breathe as slowly as possible just before using your inhaler
  • Stand or sit upright when using
  • Remove the mouthpiece and inspect it to ensure it is clear of debris and objects
  • Shake the inhaler 4 or 5 times and hold the inhaler upright with your thumb on the base, breathe out
  • Place the mouthpiece in your mouth between your teeth and close your lips, do not bite it
  • Breathe in through your mouth and just after you begin your breath, press down on the top of the canister to release a puff of this medicine whilst still breathing in steadily and deeply
  • Hold your breath and take your inhaler from your mouth, continue holding your breath for a few seconds
  • It can be taken at any time of day, with or without food
  • If you are pregnant or breast-feeding, consult your doctor before using this medicine

Do not use your inhaler more often than the doctor told you to.

Video on how to use a Sirdupla Inhaler

Warnings and Precautions

Sirdupla may not be safe if taken with other medication or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT use Sirdupla:

  • If you are allergic to salmeterol and fluticasone propionate or any other ingredients in this medicine
  • If you have diabetes mellitus
  • If you have a history of heart problems
  • If you have an overactive thyroid gland
  • Low potassium in your blood
  • Tuberculosis now or in the past, or other lung infections
  • If you are taking xanthine derivatives or steroids to treat asthma
  • If you are taking diuretics (water tablets), corticosteroids, medicines to treat infections, beta-blockers or other bronchodilators
  • If you are under the age of 18

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.


Next Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.

Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!

Product reviews

Please note the information below is intended for general knowledge, please read the patient information leaflet and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

Can I get Sirdupla on the NHS?

Whether or not you can get Sirdupla on the NHS is dependent on your local guidelines and eligibility status. It is best to contact your local GP service if you are unsure of whether you can get Sirdupla from the NHS.

Can you get Sirdupla over the counter?

No, you can’t get Sirdupla over the counter without a prescription or consultation. Sirdupla is a regulated medication so all purchases need to have a prescription and/or suitable consultation form completed.

Can I buy Sirdupla online even if I have never taken it before?

A prescribing pharmacist will need to review your consultation form before the medication can be dispatched.

Is Sirdupla safe?

If you have been prescribed Sirdupla then it is at the discretion of the prescriber.

However, all medications can potentially have adverse effects and should be taken exactly as prescribed. If you experience any side effects when taking Sirdupla then you should contact a doctor immediately.

Are there any foods that should be avoided when taking Sirdupla?

We recommend you read the patient information leaflet for this product thoroughly before taking the treatment. This is essential to understanding any interactions that can occur and to take the medication safely.

Can I buy Sirdupla from Boots?

It is generally possible to purchase medication, including Sirdupla, from UK pharmacies like Boots. However, I recommend checking the Boots website or contacting Boots directly for the most current and accurate information. Remember to consult with a healthcare professional before starting any new medication.

Can I buy Sirdupla from Superdrug?

If you would like to buy Sirdupla, you will need to check availability on the Superdrug website.

Can I buy Sirdupla from Amazon?

Amazon does not sell medication such as Sirdupla, as they are not a pharmacy service provider. Always check with Amazon to see what they sell.

How long does Sirdupla take to work?

The time it takes for a Sirdupla to work can vary greatly depending on several factors, such as the strength, the individual's age, weight, and overall health, as well as any potential interactions with other medications or substances. Generally, the effects of Sirdupla may be noticeable within the time frame outlined by the prescribing pharmacist. It is important to follow the prescribed dosage and instructions provided by your healthcare professional, and to consult them if you have any concerns or questions about the medication's efficacy or possible side effects.

How effective is Sirdupla?

The effectiveness of Sirdupla can vary significantly depending on various factors, such as the dosage, the condition being treated, the individual's age, weight, and overall health, as well as the presence of any other medications or substances that might interact with it. While some medications may be highly effective for certain individuals and conditions, others might experience a lesser degree of benefit or may require adjustments to the dosage or additional treatments to achieve the desired results.

What are the risks of taking Sirdupla?

At Welzo, we are dedicated to providing our customers with accurate and comprehensive information about medications. We believe that understanding the potential risks and side effects associated with a medication is essential for making informed decisions about your health. This guide outlines some general considerations for assessing the risks of medication and includes references to the National Health Service (NHS) for further information.

  1. Read the Patient Information Leaflet (PIL): Every medication comes with a Patient Information Leaflet, which provides essential details about the drug, its uses, and potential side effects. Be sure to read this leaflet carefully before starting any new medication. The Electronic medicines compendium has a list of patient leaflets. you can visit by heading to
  2. Be aware of potential side effects: All medications have the potential to cause side effects, ranging from mild and short-lived symptoms to more serious, long-lasting issues. It's important to understand the possible side effects of a medication and how to manage them. The NHS has a helpful resource on managing medication side effects, while also speaking to a healthcare professional is important in understanding any potential risks of taking Sirdupla.
  3. Interactions with other medications: Some medications may interact with others, leading to increased side effects or reduced effectiveness. Make sure to inform your healthcare professional about all the medications and supplements you are currently taking. The NHS offers a useful tool for checking potential drug interactions here.
  4. Contraindications and precautions: Certain medical conditions or factors may make it unsafe for you to take a particular medication. Before starting any new medication, inform your healthcare professional about your medical history and any current health issues. The NHS provides more information about contraindications and precautions here.
  5. Appropriate use and dosage: It's crucial to follow the prescribed dosage and instructions for taking a medication to ensure its effectiveness and minimise the risk of side effects. The NHS has a useful guide on using medicines safely here.
  6. Monitoring and follow-up: Some medications require regular monitoring or follow-up appointments with your healthcare professional to ensure their safety and effectiveness. Be sure to schedule and attend these appointments as needed.

Can I buy Sirdupla in the UK?

Yes, you can buy Sirdupla in the UK with a valid prescription and or consultation form. Sirdupla is available in the UK for purchase from local pharmacies with a valid prescription and or consultation. It is imperative that you ensure that the pharmacy you are buying the products from is licensed and registered with the General Pharmaceutical Council (GPhC).

Are Sirdupla users satisfied with the product?

We have a list of reviews from customers taking Sirdupla at the bottom of this page. For more information of the reviews of Sirdupla head over to for further details.

Can I buy Sirdupla from an online pharmacy?

This is dependent on your eligibility for the medication.

How much does Sirdupla cost?

The costs of Sirdupla are listed at the top of the page. Pricing is provided as a reference as we do not sell Sirdupla.

Can Sirdupla be used for those with COPD?

No, the use of Sirdupla in patients with COPD is not indicated.

What if I forget to take Sirdupla?

If you've forgotten to take Sirdupla, do not take a double dose to make up for the forgotten dose. You should take your next dose at the usual time.

Is Sirdupla a combination inhaler?

Yes, Sirdupla contains two active substances, a long-acting bronchodilator and a glucocorticosteroid. Sirdupla is also a maintenance inhaler which is inhaler designed for daily, long-term treatment of asthma. 

Does Sirdupla contain alcohol?

Yes, this product contains 0.73 mg of alcohol per inhalation which is equivalent to 12 mg/ml. However, the amount of alcohol in this dose is equivalent to less than 1 ml of beer or wine. The small amount of this medicinal product will not have any noticeable effect.

Customer Reviews

Based on 2 reviews
Moon Parlato

I appreciate the reminders I receive from when it's time to reorder my medication.

Gilma Liukko

I recently purchased the Sirdupla and I'm extremely pleased with the product. It's easy to use, effective, and has significantly improved my breathing. Highly recommend for anyone needing a reliable inhaler.