alli capsules
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Alli is a non-prescription weight-loss medication that can be effective with lifestyle and diet changes. The active ingredient orlistat helps to lessen the amount of fat absorbed by the body from an individual's food intake.

Alli is a non-prescription weight-loss medication that can be effective with lifestyle and diet changes. The active...

Alli is a non-prescription weight-loss medication that can be effective with lifestyle and diet changes. The active ingredient orlistat helps to lessen the amount of fat absorbed by the body from an individual's food intake.

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Tina Andrews reviewed
"Super fast delivery, arrived the next day with no issues. Will be using Welzo again!"
Anna Coleman reviewed
"Welzo is my go to online pharamcy. Always fast next day delivery and so easy to use!"
Benjamin Ageboli reviewed
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Alli for Weight Loss

Alli is a weight loss aid tablet which prevents fat from being digested so the extra calories from dietary intake are passed through your stools instead. Weight loss tablets are often prescribed or given when a combination of diet and lifestyle changes have not been sufficient enough for weight loss.

Weight loss medication needs to be used in conjunction with eating a balanced diet and partaking in regular exercise.

What is Alli and how does it work?

Alli is a peripherally acting medicine that contains the active ingredient orlistat. This medicine binds itself to the body's natural enzymes and breaks down some of the fats consumed in food. Alli can stop about 25% of the fat from your meals from being absorbed into the body. Instead, this fat will be passed from the body through the stools.

Alli is not recommended for pregnant or breastfeeding women.

Alli is only intended for use by adults aged 18 and over who are overweight with a body mass index (BMI) of 28 or above.

Is Alli right for me?

If you suffer from obesity, Alli may be an effective treatment. However, it may not be suitable for you if you have the following:

  • If you are allergic to orlistat or any other ingredients in this medicine
  • If you are pregnant or breastfeeding
  • If you are taking warfarin or other blood-thinning medications
  • If you are taking ciclosporin
  • If you have cholestasis
  • If you have problems absorbing food
  • If you have diabetes
  • If you have kidney disease

Side Effects

All medications can cause potential side effects, below we have listed some potential side effects of Alli. However, these do not always occur and are mostly mild in nature. But if you experience any prolonged or worrying side effects of Alli, please discontinue the medication immediately and consult your doctor.

Common side effects include:

  • Sudden bowel movements
  • Fatty or oily stools
  • Soft stools
  • Flatulence (wind), with or without oily spotting
  • Stomach (abdominal) pain
  • Incontinence
  • Runny/liquid stools
  • More frequent bowel motions
  • Anxiety

How to take Alli?

Always take Alli exactly as prescribed by your doctor or advised by the pharmacist. The recommended starting dose is three (60mg) tablets a day, however, in presence of other factors, this may be increased or decreased accordingly as per the prescriber's clinical judgement. 

  • Alli is typically taken three times a day. It should be taken immediately before, during or up to one hour after a meal
  • Swallow the capsule with water
  • The usual dose is one capsule with breakfast, lunch and dinner.
  • Alli will not work if you miss a meal, or if there is no fat in your meal.
  • If you eat a high-fat meal, do not take more than your recommended dose
  • Do not take Alli if pregnant or breast-feeding

Only 3 doses of Alli should be taken in 24 hours. Do not take more than 3 capsules a day.

Warnings and Precautions

Alli may not be safe if taken with other medication or recreational drugs. Please inform the prescriber if you are taking any of the listed medications.

DO NOT take Alli:

  • If you are allergic to orlistat or any other ingredients in this medicine
  • If you are pregnant or breastfeeding
  • If you are taking warfarin or other blood-thinning medications
  • If you are taking ciclosporin
  • If you have cholestasis
  • If you have problems absorbing food
  • If you have diabetes
  • If you have kidney disease

The above-listed warnings are not exhaustive, please consult a doctor, pharmacist or nurse if you have further questions on the use of this medication or potential interactions with other medicines.


Next-Day Delivery Guarantee

All orders placed before 14:00 on weekdays will be delivered the next working day. For the majority of the UK, medication will be dispatched by Royal Mail, Monday to Friday, if ordered before 14:00. Dispatches are sent using Royal Mail's Next-Day Tracked 24-Hour service. We will email you tracking information directly and you should receive your order the day after dispatch.


Our Discreet Packaging Promise

We know that many of our customers turn to us when they need personal medication, preferring to use our online service rather than shopping for the product face to face. That is why our delivery is always discreetly packaged in plain brown boxes or enveloped. You will not have to worry about any content descriptions, and the package will be for your eyes only!

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Alli General Information

How effective is Alli for weight loss?

Alli's effectiveness in promoting weight loss has been scientifically proven. As an over-the-counter version of the prescription drug orlistat, it works by inhibiting fat absorption in the body. Clinical dietitian, Dr. Sarah Brewer, elaborates, "Patients using Alli can expect to lose an additional 1kg for every 2kg lost through dieting alone." This indicates a substantial benefit to those seeking assistance in their weight loss journey. However, effectiveness varies among individuals and is significantly influenced by adherence to a low-fat diet and regular physical activity.

Alli weight loss reviews before and after

Reviews for Alli often exhibit significant weight loss transformations. It is common for users to report noticeable weight loss results within just a few weeks. According to a 2022 survey, 60% of Alli users reported achieving their target weight loss within six months of regular use. While these reviews reflect the potential of Alli, individual results can vary depending on factors such as diet, exercise, and initial weight.

Alli Results After Two Weeks

Alli often starts to show results within the first two weeks. These early results typically manifest as a reduction in weight, often accompanied by a noticeable decrease in waist circumference. "This early response can be motivating for users, encouraging adherence to healthy habits and the continued use of Alli," explains dietitian Dr. Carrie Ruxton. Remember that everyone's body responds differently to weight loss supplements, and it's important to have realistic expectations and patience throughout the process.

Alli Dosage & Usage

How much Alli to take (dosage)?

The standard dosage of Alli is one 60mg capsule three times a day with meals containing fat. Nutritionist Dr. Marilyn Glenville emphasises the importance of taking Alli with meals to maximise its efficacy. "Alli works by reducing fat absorption in the gut, therefore taking it with meals ensures it can work effectively on the dietary fat consumed," she explains. The maximum dose of Alli should not exceed three capsules a day, unless advised otherwise by a healthcare professional.

How much weight will I lose in a week on Alli?

The weight loss associated with Alli can vary widely among individuals. On average, individuals may lose 1-2 pounds per week when combined with a low-fat diet and exercise. Dr. Sarah Brewer explains, "This range reflects the average weekly weight loss in most clinical trials with Alli." It is important to note that weight loss may not be consistent from week to week and individual results will depend on factors such as dietary intake and physical activity levels.

When should you not take Alli?

Alli is not suitable for everyone. It is not recommended for those who are pregnant, breastfeeding, or have a BMI below 28. Furthermore, Dr. Megan Rossi explains, "People with malabsorption issues or those on certain medications, like cyclosporine or levothyroxine, should avoid Alli due to potential drug interactions and side effects." It's crucial to consult with a healthcare professional before starting any new medication, including Alli, to ensure it is safe and suitable for your specific health circumstances.

How long does Alli last?

The effects of Alli can last for up to several hours following ingestion. Dr. Carrie Ruxton points out, "Alli works locally in the stomach and small intestine for about two to four hours after consumption." However, its impact on weight loss is longer-lasting, particularly when paired with a balanced diet and regular exercise.

How long does Alli take to work?

The onset of Alli's effects is typically within 24 to 48 hours of the first dose. However, weight loss usually takes longer to become noticeable. Dr. Sarah Brewer advises, "Initial weight loss can be observed within two weeks, but significant results usually require two to three months." It's important to maintain a balanced diet and regular exercise regimen for Alli to work effectively.

How long do I need to take Alli for?

The duration of Alli usage varies among individuals and depends on the weight loss goal. "It's common to use Alli for six months to a year," states nutritionist Dr. Marilyn Glenville. If weight loss is not achieved after 12 weeks of Alli use, it is recommended to discontinue use and consult a healthcare professional. It's essential to remember that Alli is designed to complement a low-fat diet and regular exercise, not replace them. Long-term success in weight management requires consistent adherence to a healthy lifestyle.

Alli Availability & Pricing

Is Alli available in the UK?

Yes, Alli is available in the UK. It was approved for over-the-counter sale by the Medicines and Healthcare Products Regulatory Agency (MHRA) in 2009. Today, it remains a popular choice for individuals seeking weight management assistance. As pharmacist Kevin Noble explains, "Alli has proven to be an accessible and effective weight loss aid for many in the UK."

Cheapest place to buy Alli

The cost of Alli can vary significantly depending on where it's purchased. Supermarkets, pharmacies, and online retailers all offer varying prices. It's recommended to compare prices across several trusted platforms to find the most affordable option. Dr. Kevin Noble advises, "While price is important, consider also the credibility and customer service of the seller."

Can I buy Alli online?

Yes, Alli can be purchased online from various reputable pharmacies and retailers. It's essential to ensure that the chosen retailer is reputable to avoid counterfeit products. Dr. Marilyn Glenville reminds us that, "Online purchases, while convenient, require careful scrutiny to ensure the safety and quality of products."

Can I get Alli over the counter?

Alli is available over the counter without a prescription. It was the first weight loss drug to receive approval for over-the-counter sale by the MHRA. As Dr. Sarah Brewer explains, "This over-the-counter availability has made Alli a popular option for many seeking assistance with weight management."

Does Holland and Barrett sell Alli?

While Holland and Barrett stock a wide range of health and wellness products, they do not currently stock Alli. Dr. Megan Rossi adds, "It's always wise to check with individual retailers for their latest stock and product availability."

Alli Side Effects & Considerations

What to do if you get Alli side effects

If Alli side effects occur, it's important to assess their severity. Mild side effects such as minor stomach discomfort or changes in bowel habits may be manageable. However, if these side effects persist or become severe, Dr. Carrie Ruxton advises to "discontinue use and consult a healthcare professional immediately."

Alternatives & Related Treatments

Alli Vs Xenical

Alli and Xenical contain the same active ingredient, orlistat, but in different doses. Alli contains 60mg of orlistat and is available over the counter, while Xenical contains 120mg and requires a prescription. Dr. Justine Hextall clarifies, "Both can be effective for weight loss, but a healthcare professional can advise on the most suitable option."

Alli Vs Orlistat

Alli is a brand name of the generic drug orlistat. As Dr. Marilyn Glenville explains, "Both Alli and orlistat work in the same way and can have similar effectiveness. The choice between them can often come down to price and availability."

Alli Vs Saxenda

Alli and Saxenda are both weight loss aids, but they work differently. While Alli blocks fat absorption in the gut, Saxenda is a prescription injection that regulates appetite. "Saxenda is often used when diet and exercise have failed and carries a higher risk of side effects," notes Dr. Sarah Brewer. A healthcare professional can provide guidance on the best treatment option based on individual health status and weight loss goals.

Alli FAQ's

How effective is Alli?

Alli is clinically proven to be an effective weight loss aid when used in conjunction with a reduced-calorie, low-fat diet and regular exercise. Dr. Kevin Noble, a reputable pharmacist, says, "Alli users can expect to lose an additional kilogram for every two kilograms lost through their own efforts." However, it's important to remember that individual weight loss results can vary.

What are Alli horror stories?

'Alli horror stories' typically refer to the experiences of users who've had significant side effects or didn't achieve the desired weight loss. Some people report severe gastrointestinal symptoms, while others may have not lost weight despite adhering to the recommended low-fat diet and exercise. Like all medications, Alli is not without potential side effects. These can be mitigated by following the recommended low-fat diet.

Can I take 2 Alli instead of 1 xenical?

Alli and Xenical both contain the active ingredient orlistat, but in different doses. Xenical contains 120mg of orlistat, while Alli contains 60mg. Therefore, taking two Alli tablets would provide a similar dose of orlistat as one Xenical tablet. However, Dr. Sarah Brewer strongly advises against this, saying, "It's important to only take the recommended dose of any medication, including Alli. Always follow the dosage instructions given by the manufacturer or your healthcare provider."

What medication stops fat absorption?

Alli, also known by its generic name orlistat, is a medication that stops fat absorption. It works by inhibiting the action of lipases, enzymes in the digestive tract that break down dietary fats into smaller molecules that can be absorbed by the body. By inhibiting lipase action, Alli reduces the amount of dietary fat that the body can absorb, thereby reducing calorie intake and promoting weight loss. It's crucial to note that Alli should be used in conjunction with a balanced, reduced-fat diet to manage potential gastrointestinal side effects and support overall health.

Please note the information below is intended for general knowledge, please read the manufacturer guidelines and/or the information provided by a healthcare professional for more specific guidance. This information should not substitute medical advice.

Buy Alli online with Welzo and receive your order with express shipping directly to your address of choice. Welzo is the UK's leading online pharmacy and home health testing platform, with over 3000 items available online. Welzo is an approved seller of Alli. Order Alli to the comfort of your home.

Can I buy Alli in the UK?

Yes, Alli is available to purchase in the United Kingdom. You will be able to purchase Alli both from your local store/pharmacy or online.

Where can I buy Alli?

You can buy Alli online and in-store from your local pharmacy. Alli is also available with express shipping from

How to use Alli

To use Alli correctly, it is important to follow the instructions/information leaflet that comes with the product. Read all of the information thoroughly before taking the product. If you have any further questions about how to take Alli, please contact Welzo via the help centre and we will be happy to help.

What is Alli?

For more information on Alli scroll up to the description at the top of the product page which will give more insight into what Alli is.

What is the shelf life of Alli?

The shelf life of Alli can be determined by reading the expiry date on the product itself. Other factors such as storage conditions can impact the shelf life of Alli.

How should I store Alli?

Alli should be stored as per the manufacturer guidelines and information leaflet that comes with the product packaging.

When storing an over-the-counter (OTC) medication, it is crucial to follow the guidelines listed below in order to ensure the safety and effectiveness of the medicine:

  1. Read the label of Alli: Always read the label and/ or manufacturer guidelines that comes with Alli for specific storage instructions, as different products may require unique conditions.
  2. Keep in a cool, dry place: Generally, most OTC medications should be stored in a cool, dry place, away from direct sunlight, heat, and moisture. Avoid storing medicines in a bathroom cabinet or near a radiator, as temperature and humidity fluctuations may affect their potency.
  3. Maintain proper temperature: The ideal temperature for storing most medications is between 15°C and 25°C. If a specific temperature range is recommended on the label of Alli, make sure to follow it closely.
  4. Use original packaging of Alli: Keep the medication in its original container or packaging, which often provides protection from light and moisture. Additionally, original packaging usually contains important information such as the expiry date, dosage instructions, and potential side effects.
  5. Keep out of reach of children: Store medications in a secure location that is out of sight and reach of children to prevent accidental ingestion or misuse.
  6. Monitor expiry dates: Regularly check the expiry dates of your OTC medications and dispose of any expired or unused medication safely, in accordance with local regulations or your pharmacist's advice.

How should I take Alli?

When taking an over-the-counter (OTC) medication or supplement, it is essential to follow the guidelines below to ensure safety and achieve the desired results:

  1. Read the label: Carefully read the label or enclosed leaflet that comes with the Alli for specific instructions on dosage, frequency, and any potential side effects or interactions.
  2. Follow dosage recommendations: Adhere to the recommended dosage and avoid taking more than the suggested amount, as this may lead to adverse effects or reduced effectiveness.
  3. Take with or without food: Some medications or supplements may require consumption with food to aid in absorption or prevent stomach irritation, while others should be taken on an empty stomach. Follow the instructions provided on the label or leaflet of Alli.
  4. Be mindful of timing: Take the medication or supplement at the specified intervals or times of day, as recommended on the label, to ensure optimal effectiveness.
  5. Check for interactions: If you are taking multiple medications or supplements, consult your pharmacist or healthcare professional to ensure there are no potential interactions that could affect their efficacy or cause adverse effects.
  6. Monitor side effects: If you experience any unusual or severe side effects while taking the medication or supplement, discontinue use and consult your healthcare professional immediately.
  7. Seek professional advice: If you have any concerns or questions about taking a specific medication or supplement, consult your pharmacist or healthcare professional for further guidance.

What are the side effects of Alli?

The side effects of an over-the-counter (OTC) medication or supplement can be diverse, and may include mild, moderate, or severe reactions.

If you are taking Alli for the first time, it is important to monitor any adverse or allergic reactions. Ensure you are not allergic to any of the ingredients in Alli before taking. If you experience an allergic reaction please discontinue use of Alli and seek immediate medical attention.

For information on the specific side effects of Alli read the information leaflet/label that comes with Alli.

It is important to note that not everyone will experience side effects, and the severity or type of side effects may differ from person to person. Factors such as individual sensitivity, dosage, and interactions with other medications or supplements can influence the occurrence and intensity of side effects.

If you encounter any concerning side effects while taking Alli, stop using the product and consult a healthcare professional promptly. They can advise you on whether it is safe to continue using the product or recommend an alternative treatment.

Always consult a pharmacist or healthcare professional before starting any new OTC medication or supplement, particularly if you have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

How does Alli work?

The way an over-the-counter (OTC) medication or supplement works depends on the active ingredients it contains, as well as the intended purpose of the product. Generally, OTC medications and supplements are formulated to target specific symptoms, conditions, or to support overall health and well-being.

Can Alli be used by children and infants?

Read the information leaflet/label of Alli to find out if it can be used by children/infants. Furthermore, it depends on various factors, including the child's age, weight, health conditions, and the specific product in question. It is essential to exercise caution when administering any medication or supplement to a child.

  1. Read the label: Carefully examine the label or enclosed leaflet of the Alli for information on age restrictions, dosages, and any specific warnings or contraindications for children.
  2. Age-appropriate products: Some OTC medications and supplements are specifically formulated for children, with adjusted dosages and child-friendly forms, such as chewable tablets, liquid suspensions, or gummies. Opt for these products when available and follow the instructions provided for the child's age group.
  3. Consult a healthcare professional: If you are unsure whether Alli is suitable for your child, it is always best to consult a pharmacist, doctor, or paediatrician for advice. They can provide guidance on the appropriateness, dosage, and potential side effects of the product for your child.
  4. Monitor for side effects: Children may be more susceptible to side effects or adverse reactions from medications or supplements. Closely observe your child for any signs of side effects or discomfort, discontinue use and consult a healthcare professional if you have any concerns.

What happens if Alli is taken without eating?

The medicine should be taken either with your meal or up to 1 hour after eating. If you have skipped any meals then you should skip the Alli dose also.

What type of food can you eat whilst taking Alli?

It is important to have a healthy diet and continue eating 3 meals a day whilst ingesting Alli tablets.

Is this medication suitable for me?

Please get in touch with a doctor if you are unsure what medication is suitable for you. You can also complete our online consultation form to check your eligibility for the product.

How is the medication delivered?

All orders placed before 14:00 from Monday to Friday will be dispatched that day. The orders are sent using 24 Hour Tracked delivery provided by Royal Mail. Items will usually arrive the very next day after the order has been placed. We also provide tracking for your orders to check the status and location of your parcel. All our medication is packaged in plain confidential padded white or brown envelopes. This ensures that your orders are discreet, and the content of the orders will be for your eyes only.

Can Alli be used on a long-term basis?

Alli should not be taken for longer than six months at a time.

How long does it take to see results?

Alli must be used for up to three months in order to see the results of weight loss.

How do I order my medication?

Some products only require an online consultation which approximately takes 1 minute to complete, enabling you to then buy the product. Other products will also require a prescription; in this case, you will need to complete the online consultation, and then one of our partner pharmacy prescribers or doctors will review the online consultation questions and approve the order for delivery if you are eligible to purchase the item.

Can I cancel or return my order?

For non-medicinal products, you are eligible to return the product within 14 days of receipt in the same packaging you received. For medicinal products, you are eligible to cancel the order only until it has been dispatched. From that point forward, you are no longer eligible to return the order.

You have the right to cancel your order for medication up to the point when your medication is dispatched.

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Martina Staback

The pharmacy team should be able to offer guidance on how to properly store and dispose of medication.