What Is More Effective Tadalafil Or Sildenafil?

Tadalafil and Viagra
Sildenafil and Tadalafil are oral medications that are used to treat an enlarged prostate or benign prostatic hyperplasia (BPH) and impotence (the inability to sustain a penile erection). They are of the phosphodiesterase-5 (PDE5) inhibitor class, along with avanafil (Stendra) and vardenafil (Levitra, Staxyn ODT).


A penile erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation generates and emits nitric oxide in the penis. The enzyme guanylate cyclase is activated, resulting in (cGMP) cyclic guanosine monophosphate formation. The cGMP is primarily responsible for erections by influencing the blood pressure given and taken from the penis by the blood vessels. Cialis and Viagra block the enzyme phosphodiesterase-5 (PDE5), breaking cGMP.

Cialis and Viagra block the destruction of cGMP, allowing it to build and persist for a more extended period. The longer cGMP is present, the longer the penile engorgement lasts.

What Is Tadalafil?

The generic name for the drug Cialis "weekend pill" is tadalafil. Tadalafil Daily is a once-daily low-dose drug that helps you obtain an erection at night or day. Generic Tadalafil 36-hour should be taken 15-20 minutes before sexual activity. The typical retail price of generic tadalafil for a 2.5 mg dosage is about $275 for 30 pills.

Moreover, it's possible that taking tadalafil or sildenafil after a meal may lengthen the time required to function. Sildenafil and tadalafil work best when taken on an unbalanced diet.

What Is Sildenafil?

Viagra is the most well-known drug for treating erectile dysfunction and has been on the market for more than 15 years. The FDA has only authorized Viagra for the treatment of erectile dysfunction. The active component in Viagra, sildenafil citrate, is also used to address pulmonary arterial hypertension (PAH). Millions of men all around the globe have demonstrated that it is a very successful treatment for erectile dysfunction. Furthermore, Sildenafil, a generic brand of Viagra, has been marketed since 2013. As a result, the cost of sildenafil has dramatically decreased.

How DoTadalafil and Sildenafil Work?

Tadalafil and Sildenafil are considered PDE5 inhibitors. When sexually aroused, the PDE-5 family of medicines preserves a relaxed muscular condition while increasing blood flow to the penis to aid in erection formation. PDE5 inhibitors don't increase sexual desire or interest; they treat erectile dysfunction's physical effects.

Additionally, both Tadalafil and Sildenafil are classified in the same class known as PDE-5 inhibitors. While the theory behind each is similar, there are several key differences that may influence your decision. When sexually aroused, the PDE-5 group of medicines preserves a relaxed muscular condition while increasing blood flow to the penis to aid in erection formation. PDE-5 inhibitors are only used to treat the physical effects of erectile dysfunction and thus do not increase sex drive or pleasure.

Which Is More Effective in Treating Erectile Dysfunction?

Tadalafil lasts longer than Viagra (Sildenafil). Sildenafil has an action time of up to 4 hours, while tadalafil has 36 hours. This does not imply that you will have a consistent erectile function throughout the periods when each medicine is active. It indicates that you will have an erection when sexually aroused for the duration of the drug interactions. Also, Tadalafil 2.5mg and 5mg (tadalafil daily) may be used every day and are recommended for men who have more than two sexual interactions each week.

Moreover, tadalafil is a more modern and effective ED medication. It looks to outperform Viagra in terms of the most desired characteristics for an erectile dysfunction medicine, such as duration, the commencement of the action, and side effects.

Tadalafil works 10-20 minutes faster than sildenafil on average. Sildenafil takes effect 30-60 minutes after taking, while tadalafil takes effect 20-30 minutes after taking. This might vary depending on the person and how they react to each ED treatment. Tadalafil and sildenafil perform best when taken on an empty stomach. Taking sildenafil or tadalafil after a meal will most likely cause it to take longer to work.

Furthermore, tadalafil is better than sildenafil since it has many benefits; the most notable is its longer duration of effect. It also acts quicker than sildenafil and has fewer negative effects. While both treatments work better on an empty stomach, tadalafil is less affected by food than sildenafil. However, the fact is that people react differently to various treatments. Despite having tried tadalafil, some men prefer sildenafil and vice versa. Look at the sildenafil reviews and tadalafil reviews sites to discover how our customers rank each treatment.

Can You Take Them Together?

Both Sildenafil and Tadalafil should never be used together to treat ED. It's also common practice to take either one just before sexual activity, but not daily. These ED prescription drugs only function if you're currently sexually active. Cialis and Viagra must be taken with any prescription that can affect low blood pressure. These possess alpha-blockers, nitrates, and blood pressure-lowering drugs.

Sildenafil and tadalafil cannot be used simultaneously or on the same day. Taking several ED medications simultaneously or on the same day might result in undesirable and sometimes harmful side effects. Indigestion, nausea, dizziness, and an erection lasting more than 4 hours are possible symptoms. However, you may apply both treatments on separate days.

How Will I Know Which One to Use?

The only way to determine whether to take Viagra (sildenafil) or tadalafil to treat erectile dysfunction is to try both. It would help if you talked with a doctor or pharmacist to choose which one to try. This might be affected by various factors related to sexual activity and interests. If you've taken one drug, you must try it a few more times to get your body adjusted to it.

Moreover, if you aren't getting the desired results, try a greater strength the following time. If you've reached the maximum power and used it a few times without getting the desired effect, talk to a pharmacist or doctor about attempting an alternative.

Side Effects of Sildenafil and Tadalafil


If you are taking Viagra and experience dizziness, chest pain, or nausea during sex, get medical attention or professional medical advice immediately as you may be suffering from a possibly fatal condition.

Approximately 15% of people who use Viagra develop adverse effects. The most prevalent side effects may include:


If you are taking Cialis and experience muscle pain, dizziness, chest pain, or nausea during sex, get medical attention immediately as you may be suffering from a potentially fatal disease.

The following are the most prevalent tadalafil side effects:

  • Headaches
  • Diarrhoea
  • Nausea
  • Facial flushing
  • Stomach upset
  • Flu-like symptoms

Tadalafil may also cause:

  • Premature ejaculation
  • Blurred vision
  • Low blood pressure
  • Changes in colour vision
  • Priapism

Is It Safe to Use Sildenafil and Tadalafil When Breastfeeding or Pregnant?


Although comprehensive animal research has shown that Viagra has no adverse effects on the fetus, it has not been evaluated in pregnant women. In men, there is no impact on sperm count or motility.

It is unknown whether sildenafil is secreted in breast milk.


Tadalafil is not approved for women and has not been studied in breastfeeding women.


For a full range of medications including Viagra and Tadalafil, visit our Welzo Online Pharmacy Page.

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